Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chin I Pai"'
Autor:
Xia Cao, Junki Maruyama, Heyue Zhou, Yanwen Fu, Lisa Kerwin, Colin Powers, Rachel A. Sattler, John T. Manning, Alok Singh, Reyna Lim, Laura D. Healy, Sachi Johnson, Elizabeth Paz Cabral, Donghui Li, Lucy Lu, Arthur Ledesma, Daniel Lee, Susan Richards, Laura Rivero-Nava, Yan Li, Weiqun Shen, Karen Stegman, Benjamin Blair, Shinji Urata, Magumi Kishimoto-Urata, Jamie Ko, Na Du, Kyndal Morais, Kate Lawrence, Ianne Rivera, Chin-I. Pai, Damien Bresson, Mark Brunswick, Yanliang Zhang, Henry Ji, Slobodan Paessler, Robert D. Allen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Coronavirus disease 2019 (COVID-19) continues to significantly impact the global population, thus countermeasure platforms that enable rapid development of therapeutics against variants of SARS-CoV-2 are essential. We report use of a phage d
Externí odkaz:
https://doaj.org/article/37fca7f29c8b45c4a5a9a070e9d4f804
Autor:
J. Andrew Duty, Thomas Kraus, Heyue Zhou, Yanliang Zhang, Namir Shaabani, Soner Yildiz, Na Du, Alok Singh, Lisa Miorin, Donghui Li, Karen Stegman, Sabrina Ophir, Xia Cao, Kristina Atanasoff, Reyna Lim, Ignacio Mena, Nicole M. Bouvier, Shreyas Kowdle, Juan Manuel Carreño, Laura Rivero-Nava, Ariel Raskin, Elena Moreno, Sachi Johnson, Raveen Rathnasinghe, Chin I. Pai, Thomas Kehrer, Elizabeth Paz Cabral, Sonia Jangra, Laura Healy, Gagandeep Singh, Prajakta Warang, Viviana Simon, Emilia Mia Sordillo, Harm van Bakel, Yonghong Liu, Weina Sun, Lisa Kerwin, John Teijaro, Michael Schotsaert, Florian Krammer, Damien Bresson, Adolfo García-Sastre, Yanwen Fu, Benhur Lee, Colin Powers, Thomas Moran, Henry Ji, Domenico Tortorella, Robert Allen
Publikováno v:
Med (New York, N.Y.). 3(10)
The continual emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, in particular the newly emerged Omicron (B.1.1.529) variant and its BA.X lineages, has rendered ineffective a number of previously FDA emerge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9023a9ea9333e0aac6a98e5e560ddfa8
https://pubmed.ncbi.nlm.nih.gov/36044897
https://pubmed.ncbi.nlm.nih.gov/36044897
Autor:
J. Andrew Duty, Thomas Kraus, Heyue Zhou, Yanliang Zhang, Namir Shaabani, Soner Yildiz, Na Du, Alok Singh, Lisa Miorin, Donghui Li, Karen Stegman, Sabrina Ophir, Xia Cao, Kristina Atanasoff, Reyna Lim, Shreyas Kowdle, Juan Manuel Carreño, Laura Rivero-Nava, Ariel Raskin, Elena Moreno, Sachi Johnson, Raveen Rathnasinghe, Chin I Pai, Thomas Kehrer, Elizabeth Paz Cabral, Sonia Jangra, Laura Healy, Gagandeep Singh, Prajakta Warang, Viviana Simon, Mia Emilia Sordillo, Harm van Bakel, Yonghong Liu, Weina Sun, Lisa Kerwin, Peter Palese, John Teijaro, Michael Schotsaert, Florian Krammer, Damien Bresson, Adolfo García-Sastre, Yanwen Fu, Benhur Lee, Colin Powers, Thomas Moran, Henry Ji, Domenico Tortorella, Robert Allen
The continual emergence of SARS-CoV-2 variants of concern, in particular the newly emerged Omicron (B.1.1.529) variant, has rendered ineffective a number of previously EUA approved SARS-CoV-2 neutralizing antibody therapies. Furthermore, even those a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afdbf0b1baf428680010d00a276bb180
https://doi.org/10.1101/2022.01.19.476998
https://doi.org/10.1101/2022.01.19.476998
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004992 (2015)
A complex program of translational repression, mRNA localization, and translational activation ensures that Oskar (Osk) protein accumulates only at the posterior pole of the Drosophila oocyte. Inappropriate expression of Osk disrupts embryonic axial
Externí odkaz:
https://doaj.org/article/a962f35f10354c40b2a43d443ede0b7e
Autor:
Xia Cao, Kenneth Kim, Andrew J. Gonzalez, Kristen M. Valentine, Chin-I Pai, Heyue Zhou, Sachi Johnson, Sujan Shresta, Lisa Kerwin, Lucy Lu, Yanliang Zhang, Michael N. Nguyen, Norazizah Shafee, Robert D. Allen, Ying-Ting Wang
Publikováno v:
Antiviral Research
Monoclonal antibodies (mAbs) are emerging as safe and effective therapeutics against SARS-CoV-2. However, variant strains of SARS-CoV-2 have evolved, with early studies showing that some mAbs may not sustain their efficacy in the face of escape mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4294b11b68ced20f6184a5ea2cffdf62
https://pubmed.ncbi.nlm.nih.gov/34634289
https://pubmed.ncbi.nlm.nih.gov/34634289
Autor:
Yan Li, Sachi Johnson, John T. Manning, Xia Cao, Yanliang Zhang, Chin I. Pai, Slobodan Paessler, Henry Ji, Heyue Zhou, Benjamin Blair, Richards Susan M, Lucy Lu, Katherine E. Lawrence, Rachel A. Sattler, Robert D. Allen, Junki Maruyama, Na Du, Kyndal Morais, Lisa Kerwin, Donghui Li, Weiqun Shen, Mark Brunswick
SARS-CoV-2 neutralizing antibodies represent an important component of the ongoing search for effective treatment of and protection against COVID-19. We report here on the use of a naïve phage display antibody library to identify a panel of fully hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90d54153676b3e8a0540ae63cd21a27
https://doi.org/10.1101/2020.09.27.316174
https://doi.org/10.1101/2020.09.27.316174
Autor:
Xiaokui Zhang, Lin Kang, Chin-I Pai, Henry Ji, Valentina Rousseva, Yanliang Zhang, Guo Wenzhong, Irene Raitman, William van der Touw, Qian Ye, Robert J. Hariri, Joseph Gleason, Marina Gergues, Shuyang He
Publikováno v:
Blood. 138:2779-2779
Background: Natural killer (NK) cells exhibit anti-tumor activity in a non-antigen-specific manner without causing graft-versus-host disease. T cell and cord blood NK cells expressing chimeric antigen receptor (CAR) targeting CD19 have demonstrated r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e1c5fc053587f7ec70ef2947173ebbb
https://doi.org/10.1182/blood-2021-150593
https://doi.org/10.1182/blood-2021-150593
Publikováno v:
Developmental Cell. 18:496-502
SummaryAsymmetric positioning of proteins within cells is crucial for cell polarization and function. Deployment of Oskar protein at the posterior pole of the Drosophila oocyte relies on localization of the oskar mRNA, repression of its translation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62ae038466a5526a1be77bb1cebc696
https://doi.org/10.1016/j.devcel.2009.12.021
https://doi.org/10.1016/j.devcel.2009.12.021
Autor:
Meng Chun Hu, Nai Chi Hsu, Hsueh-Ping Chu, Bon Chu Chung, Chi-Kuang Leo Wang, Noomen Ben El Hadj, Chin I. Pai
Publikováno v:
Molecular Endocrinology. 16:1943-1950
Steroid deficiencies are diseases affecting salt levels, sugar levels, and sexual differentiation. To study steroid deficiency in more detail, we used a gene-targeting technique to insert a neo gene into the first exon to disrupt Cyp11a1, the first g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4a14ecad8acd0d01836238268a9b06
https://doi.org/10.1210/me.2002-0055
https://doi.org/10.1210/me.2002-0055
Publikováno v:
Molecular Endocrinology. 15:812-818
The CYP11A1 gene encodes P450scc (cholesterol side-chain cleavage enzyme), which catalyzes the first step for the synthesis of steroids. Expression of CYP11A1 is controlled by transcription factor SF-1 (steroidogenic factor 1). Two functional SF-1-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b69f1811943e9228b583a5cd394b44
https://doi.org/10.1210/mend.15.5.0636
https://doi.org/10.1210/mend.15.5.0636