Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Chin Hin, Ng"'
1
Akademický článek
NanoVar: accurate characterization of patients’ genomic structural variants using low-depth nanopore sequencing
Autor: Cheng Yong Tham, Roberto Tirado-Magallanes, Yufen Goh, Melissa J. Fullwood, Bryan T.H. Koh, Wilson Wang, Chin Hin Ng, Wee Joo Chng, Alexandre Thiery, Daniel G. Tenen, Touati Benoukraf
Publikováno v: Genome Biology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract The recent advent of third-generation sequencing technologies brings promise for better characterization of genomic structural variants by virtue of having longer reads. However, long-read applications are still constrained by their high seq
Externí odkaz: https://doaj.org/article/34a655772a22470fb24f4fe43e3bcc5f
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2
Akademický článek
PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein
Autor: Min Thura, Abdul Qader Al-Aidaroos, Abhishek Gupta, Cheng Ean Chee, Soo Chin Lee, Kam Man Hui, Jie Li, Yeoh Khay Guan, Wei Peng Yong, Jimmy So, Wee Joo Chng, Chin Hin Ng, Jianbiao Zhou, Ling Zhi Wang, John Shyi Peng Yuen, Henry Sun Sien Ho, Sim Mei Yi, Edmund Chiong, Su Pin Choo, Joanne Ngeow, Matthew Chau Hsien Ng, Clarinda Chua, Eugene Shen Ann Yeo, Iain Bee Huat Tan, Joel Xuan En Sng, Nicholas Yan Zhi Tan, Jean Paul Thiery, Boon Cher Goh, Qi Zeng
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Phosphatase of regenerating liver 3 (PRL3) is usually found intracellularly, and is over-expressed in cancer cells. Here the authors show that PRL-3 is also detectable on cell surface, and can be recognized by PRL3-zumab to recruit immune cells into
Externí odkaz: https://doaj.org/article/a0d6749bcea14e23bb0de1ac495322d3
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4
Akademický článek
A case of blackwater fever with persistent Plasmodium falciparum parasitaemia detected by PCR after artemether–lumefantrine treatment
Autor: Paul John Huggan, Chin Hin Ng, Jennifer Ho, Raymond Tzer Pin Valentine Lin, Jean-Marc Chavatte
Publikováno v: Malaria Journal, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background Blackwater fever is a complication of malaria infection consisting of a syndrome of febrile intra-vascular haemolysis with severe anaemia and intermittent passage of dark-red to black colour urine. Despite numerous reports and stu
Externí odkaz: https://doaj.org/article/195c36e14ed84c93ad5338bdf60c41d2
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5
Akademický článek
Cost-Effectiveness of Serum Galactomannan Surveillance during Mould-Active Antifungal Prophylaxis
Autor: Ai Leng Khoo, Ying Jiao Zhao, Glorijoy Shi En Tan, Monica Teng, Jenny Yap, Paul Anantharajah Tambyah, Chin Hin Ng, Boon Peng Lim, Louis Yi Ann Chai
Publikováno v: Journal of Fungi, Vol 7, Iss 6, p 417 (2021)
Serial galactomannan (GM) monitoring can aid the diagnosis of invasive aspergillosis (IA) and optimise treatment decisions. However, widespread adoption of mould-active prophylaxis has reduced the incidence of IA and challenged its use. We evaluated
Externí odkaz: https://doaj.org/article/ddfdef45a1ff40ae83842c80de46bda2
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7
Akademický článek
Recent advances in acute promyelocytic leukaemia [version 1; referees: 3 approved]
Autor: Chin-Hin Ng, Wee-Joo Chng
Publikováno v: F1000Research, Vol 6 (2017)
Acute promyelocytic leukaemia (APML) is a subtype of leukaemia arising from a distinct reciprocal translocation involving chromosomes 15 and 17, which results in the PML-RARA fusion gene. Over the past three decades, APML has been transformed from a
Externí odkaz: https://doaj.org/article/91c1bb2e68724b7689aec1421b3f8d1c
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8
Cost-Effectiveness of Serum Galactomannan Surveillance during Mould-Active Antifungal Prophylaxis
Autor: Ying Jiao Zhao, Chin Hin Ng, Glorijoy Shi En Tan, Jenny Yap, Paul A. Tambyah, Boon Peng Lim, Ai Leng Khoo, Louis Yi Ann Chai, Monica Teng
Publikováno v: Journal of Fungi
Volume 7
Issue 6
Journal of Fungi, Vol 7, Iss 417, p 417 (2021)
Serial galactomannan (GM) monitoring can aid the diagnosis of invasive aspergillosis (IA) and optimise treatment decisions. However, widespread adoption of mould-active prophylaxis has reduced the incidence of IA and challenged its use. We evaluated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a0f7c109c69bf628fa9ea5ab147ee6
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9
NanoVar: accurate characterization of patients’ genomic structural variants using low-depth nanopore sequencing
Autor: Bryan T. H. Koh, Alexandre H. Thiery, Daniel G. Tenen, Touati Benoukraf, Wee Joo Chng, Wilson Wang, Yufen Goh, Roberto Tirado-Magallanes, Melissa J. Fullwood, Cheng Yong Tham, Chin Hin Ng
Publikováno v: Genome Biology, Vol 21, Iss 1, Pp 1-15 (2020)
Genome Biology
Despite the increasing relevance of structural variants (SV) in the development of many human diseases, progress in novel pathological SV discovery remains impeded, partly due to the challenges of accurate and routine SV characterization in patients.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa08848feb786ca7dd1c46487540c6b
https://doi.org/10.1186/s13059-020-01968-7
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10
Clinical outcomes and survival of patients with myeloma and lymphoma enrolled into phase I clinical trials
Autor: Chin‐Hin Ng, Dima El-Sharkawi, Rakesh Popat, Elspeth M. Payne, Asim Khwaja, Kirit M. Ardeshna, William Townsend, Kwee Yong
Publikováno v: British Journal of Haematology. 185:344-347
Phase I clinical trials are primarily designed to assess the safety and toxicity of a new agent and determine the recommended dose for further trials that assess efficacy. Patients entering these trials typically have multiply relapsed or refractory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8067135159af0dcc9d8067a84e5fd161
https://doi.org/10.1111/bjh.15457
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