Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chin Fung Kelvin Kan"'
Autor:
Caleb E. Stewart, Chin Fung Kelvin Kan, Brody R. Stewart, Henry W. Sanicola, Jangwook P. Jung, Olawale A. R. Sulaiman, Dadong Wang
Publikováno v:
Journal of Biological Engineering, Vol 14, Iss 1, Pp 1-19 (2020)
Abstract Nerve guidance conduits (NGCs) have emerged from recent advances within tissue engineering as a promising alternative to autografts for peripheral nerve repair. NGCs are tubular structures with engineered biomaterials, which guide axonal reg
Externí odkaz:
https://doaj.org/article/4bd253d3606d4a359a976fb9d784f5c6
Autor:
Chin Fung Kelvin Kan, Graham D. Unis, Luke Z. Li, Susan Gunn, Li Li, H. Peter Soyer, Mitchell S. Stark
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Lung cancer is currently the leading cause of cancer death in both developing and developed countries. Given that lung cancer has poor prognosis in later stages, it is essential to achieve an early diagnosis to maximize patients’ overall survival.
Externí odkaz:
https://doaj.org/article/b3b16472c31f44acb9b37d96b7476711
Autor:
Chin Fung Kelvin Kan, John D. Skaggs
Publikováno v:
The Yale Journal of Biology and Medicine. 96:107-123
Autor:
Vikram Ravindra Shende, Minhao Wu, Amar Bahadur Singh, Bin Dong, Chin Fung Kelvin Kan, Jingwen Liu
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 4, Pp 801-809 (2015)
The transcription factors hepatic nuclear factor (HNF)1α and HNF1β can bind to the HNF1 site on the proprotein convertase subtilisin/kexin type 9 (PCSK9) promoter to activate transcription in HepG2 cells. However, it is unknown whether one or both
Externí odkaz:
https://doaj.org/article/7cd9eb0c5d6441ccb0771398690bff49
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 8, Pp 1657-1667 (2014)
ACSL4 is a member of the long-chain acyl-CoA synthetase (ACSL) family with a marked preference for arachidonic acid (AA) as its substrate. Although an association between elevated levels of ACSL4 and hepatosteatosis has been reported, the function of
Externí odkaz:
https://doaj.org/article/2c2e8afa4db04df8a827db3f2ce44c4c
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1397-1407 (2014)
It is well-established that over-accumulation of dietary cholesterol in the liver inhibits sterol-regulatory element binding protein (SREBP)-mediated LDL receptor (LDLR) gene transcription leading to a reduced hepatic LDLR mRNA level in hypercholeste
Externí odkaz:
https://doaj.org/article/745a0b24eae0468b8b049c9270d455f8
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 5, Pp 1241-1254 (2013)
Long-chain acyl-CoA synthetases (ACSL) play key roles in fatty acid metabolism in liver and other metabolic tissues in an isozyme-specific manner. In this study, we examined the effects of a fructose-enriched diet on expressions of ACSL isoforms in t
Externí odkaz:
https://doaj.org/article/c68b021ec6394346a5eabfa768c51191
Publikováno v:
The Yale Journal of Biology and Medicine
Dercum’s disease (DD), also described as adiposis dolorosa, is a poorly understood and rare adipose tissue disorder involving obesity and painful adipose tissue masses. Patients may have associated bruising and constitutional symptoms such as fatig
Publikováno v:
Am J Physiol Endocrinol Metab
Long-chain acyl-CoA synthetase 4 (ACSL4) has a unique substrate specificity for arachidonic acid. Hepatic ACSL4 is coregulated with the phospholipid (PL)-remodeling enzyme lysophosphatidylcholine (LPC) acyltransferase 3 by peroxisome proliferator-act
Autor:
Chin Fung Kelvin Kan, Graham D. Unis, Luke Z. Li, Susan Gunn, Li Li, H. Peter Soyer, Mitchell S. Stark
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Lung cancer is currently the leading cause of cancer death in both developing and developed countries. Given that lung cancer has poor prognosis in later stages, it is essential to achieve an early diagnosis to maximize patients’ overall survival.