Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chin Fung Chan"'
Autor:
Larry M.C. Chow, Chin-Fung Chan, Man Chun Law, Xuezhen Zhu, Tsz Cheung Chong, Zhen Liu, Tsun Sing Chow, Jiahua Cui, Kin-Fai Chan, Tak Hang Chan, Iris L. K. Wong
Publikováno v:
Journal of Medicinal Chemistry. 64:14311-14331
We synthesize various substituted triazole-containing flavonoids and identify potent, nontoxic, and highly selective BCRP inhibitors. Ac18Az8, Ac32Az19, and Ac36Az9 possess m-methoxycarbonylbenzyloxy substitution at C-3 of the flavone moiety and subs
Autor:
Michael K. Chan, Jiale Zheng, Marianne M. Lee, Zhen Liu, Tak Hang Chan, Zaofeng Yang, Iris L. K. Wong, Larry M.C. Chow, Chin Fung Chan, Xianliang Zhao
Publikováno v:
Antimicrob Agents Chemother
We have designed, synthesized, and characterized a library of 38 novel flavonoid compounds linked with amines. Some of these amine-linked flavonoids have potent in vitro activity against parasites that cause cutaneous leishmaniasis, a tropical diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1dfb6e24f4e2b298f6ae3a1abd42f6
https://europepmc.org/articles/PMC8092861/
https://europepmc.org/articles/PMC8092861/
Autor:
Wong, Iris L.K., Xuezhen Zhu, Kin-Fai Chan, Zhen Liu, Chin-Fung Chan, Tsun Sing Chow, Tsz Cheung Chong, Man Chun Law, Jiahua Cui, Chow, Larry M.C., Tak Hang Chan
Publikováno v:
Journal of Medicinal Chemistry; 10/14/2021, Vol. 64 Issue 19, p14311-14331, 21p
Targeted delivery of antimicrobial peptide by Cry protein crystal to treat intramacrophage infection
Autor:
Marianne M. Lee, Iris L. K. Wong, Jiale Zheng, Zaofeng Yang, Larry M.C. Chow, Bradley S. Heater, Michael K. Chan, Chin-Fung Chan
Publikováno v:
Biomaterials. 217:119286
Antimicrobial peptides (AMPs) have recently attracted great attention due to their rapid action, broad spectrum of activity, and low propensity of resistance development. The successful application of AMPs in the treatment of intracellular infections