Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Chin Fen Yang"'
Autor:
Elissa Malkin, Ram Yogev, Nazha Abughali, Joseph Sliman, C Kathy Wang, Fengrong Zuo, Chin-Fen Yang, Mark Eickhoff, Mark T Esser, Roderick S Tang, Filip Dubovsky
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77104 (2013)
Despite substantial morbidity associated with respiratory syncytial virus (RSV) infection, there is no licensed vaccine. MEDI-559 is a live attenuated intranasal vaccine candidate being developed for prevention of lower respiratory illness due to RSV
Externí odkaz:
https://doaj.org/article/51acecd6d9ea429382eebdb8ed9cf25a
Autor:
Stacie L Lambert, Chin-Fen Yang, Zheng Liu, Rosemary Sweetwood, Jackie Zhao, Lily Cheng, Hong Jin, Jennifer Woo
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51618 (2012)
BACKGROUND: Toll-like receptor (TLR)4 agonists are known potent immunostimulatory compounds. These compounds can be formulated as part of novel adjuvants to enhance vaccine medicated immune responses. However, the contribution of the formulation to t
Externí odkaz:
https://doaj.org/article/73aaa67ee0a44cac958c5624145a5d55
Autor:
Juan Pablo Torres, Asuncion Mejias, Octavio Ramilo, Lisa Jaramillo, Lorena I. Tapia, Hasan S. Jafri, Susana Chavez-Bueno, Melissa Moore-Clingenpeel, Mark E. Peeples, Carla Garcia, Rosa Rodríguez-Fernández, Chin Fen Yang, Pedro A. Piedra
Publikováno v:
The Journal of infectious diseases. 217(1)
Background Data on how respiratory syncytial virus (RSV) genotypes influence disease severity and host immune responses is limited. Here, we characterized the genetic variability of RSV during 5 seasons, and evaluated the role of RSV subtypes, genoty
Autor:
Lambert, Stacie L.1, Chin-Fen Yang1, Zheng Liu1, Sweetwood, Rosemary1, Zhao, Jackie1, Lily Cheng1, Hong Jin1 jinh@medimmune.com, Jennifer Woo1 wooj@medimmune.com
Publikováno v:
PLoS ONE. Dec2012, Vol. 7 Issue 12, p1-11. 11p.
Autor:
Brandon Liang, Chin-Fen Yang, Randall S. MacGill, Michael P. McCarthy, Susan Wilson, Nita K. Patel, Leslie Wachter, Qing Zhu, Lan Su, Genevieve A. Losonsky, JoAnn Suzich, Wei Zhu, Subramaniam Krishnan, Josie M. McAuliffe, Frances J. Palmer-Hill
Publikováno v:
The Journal of Infectious Diseases. 203:674-682
Respiratory syncytial virus (RSV) is a member of the Pneumovirus genus in the Paramyxoviridae family. The RSV genome consists of a negative-sense, nonsegmented, single strand of RNA encoding 10 proteins [1]. RSV is an enveloped virus, and its antigen
Publikováno v:
Journal of Virology. 84:7695-7702
H2 influenza viruses have not circulated in humans since 1968, and therefore a large segment of the population would likely be susceptible to infection should H2 influenza viruses reemerge. The development of an H2 pandemic influenza virus vaccine ca
Autor:
Chin-Fen Yang, Yuwei Zhu, Dan Ye, Richard R. Spaete, Geoffrey A. Weinberg, James E. Crowe, Peter G. Szilagyi, Caroline B. Hall, Kathryn M. Edwards, John V. Williams, David Silva, Marie R. Griffin, Chiaoyin K. Wang
Publikováno v:
The Journal of Infectious Diseases
Background Human metapneumovirus (HMPV) is a leading cause of acute respiratory illness (ARI) in children. Population-based incidence rates and comprehensive clinical characterizations of disease have not been established.
Autor:
Zhongying Chen, Amy Aspelund, Hong Jin, Celia Santos, Laura Gillim-Ross, Kanta Subbarao, Dan Ye, Chin-Fen Yang, George Kemble
Publikováno v:
Journal of Virology. 82:10854-10863
Influenza pandemic preparedness has focused on influenza virus H5 and H7 subtypes. However, it is not possible to predict with certainty which subtype of avian influenza virus will cause the next pandemic, and it is prudent to include other avian inf
Autor:
Yunjuan Sun, Yi-Bing Ouyang, Judith Frydman, Lijun Xu, Manisha Dayal, Rona G. Giffard, Chin Fen Yang
Publikováno v:
Neurobiology of Aging. 27:562-569
Protein aggregation and misfolding are central mechanisms of both acute and chronic neurodegeneration. Overexpression of chaperone Hsp70 protects from stroke in animal and cell culture models. Although it is accepted that chaperones protect cells, th
Autor:
Deborah A. Buonagurio, Thomas M. Bechert, Eduardo A. Rojas, Gail A. D'Arco, Leonid Shutyak, Mohinder Sidhu, Hai-Ping Wang, Timothy J. Zamb, Stephen A. Udem, Chin-Fen Yang, Y. Kazachkov, Kathleen L. Coelingh, Robert E. O'Neill, Richard R. Spaete
Publikováno v:
Vaccine. 24:2151-2160
FluMist® is a live-attenuated, trivalent influenza vaccine (LAIV) recently approved for intranasal administration. To demonstrate genetic stability during manufacture of the vaccine viruses in LAIV and a similar vaccine in development (CAIV-T), full