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Autor:
Sharoen Y. M. Lim, Jason Siau Ee Loo, Mustafa Alshagga, Mohammed A. Alshawsh, Chin E. Ong, Yan Pan
Publikováno v:
International Journal of Toxicology. 41:355-366
Cathine is the stable form of cathinone, the major active compound found in khat ( Catha edulis Forsk) plant. Khat was found to inhibit major phase I drug metabolizing cytochrome P450 (CYP) enzyme activities in vitro and in vivo. With the upsurge of