Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Chin Chuan Chen"'
Autor:
Jia-You Fang, Kuo-Yen Huang, Tong-Hong Wang, Zih-Chan Lin, Chin-Chuan Chen, Sui-Yuan Chang, En-Li Chen, Tai-Ling Chao, Shuenn-Chen Yang, Pan-Chyr Yang, Chi-Yuan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Introduction Angiotensin-converting enzyme 2 (ACE2) and AXL tyrosine kinase receptor are known to be involved in the SARS-CoV-2 entry of the host cell. Therefore, targeting ACE2 and AXL should be an effective strategy to inhibit virus entry
Externí odkaz:
https://doaj.org/article/d499e64a4ae440dfafb7c71ebdd6ef48
Autor:
Tong‐Hong Wang, Kuo‐Yen Huang, Chin‐Chuan Chen, Ya‐Hsuan Chang, Hsuan‐Yu Chen, Chuen Hsueh, Yi‐Tsen Liu, Shuenn‐Chen Yang, Pan‐Chyr Yang, Chi‐Yuan Chen
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 6, Pp 1-16 (2023)
Abstract Particulate matter 2.5 (PM2.5) is a risk factor for lung cancer. In this study, we investigated the molecular mechanisms of PM2.5 exposure on lung cancer progression. We found that short‐term exposure to PM2.5 for 24 h activated the EGFR p
Externí odkaz:
https://doaj.org/article/5e9ebe0cfc3745a7aea86a1c3a1d3ea3
Autor:
Tong-Hong Wang, Wei-Che Tseng, Yann-Lii Leu, Chi-Yuan Chen, Wen-Chih Lee, Ying-Chih Chi, Shu-Fang Cheng, Chun-Yu Lai, Chen-Hsin Kuo, Shu-Ling Yang, Sien-Hung Yang, Jiann-Jong Shen, Chun-Hao Feng, Chih-Ching Wu, Tsong-Long Hwang, Chia-Jen Wang, Shu-Huei Wang, Chin-Chuan Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Various traditional Chinese herbs and complex formulas have been suggested to exhibit lifespan extension properties. Here, the authors isolated the flavonoid corylin from Psoralea corylifolia and demonstrated its longevity properties in yeast, human
Externí odkaz:
https://doaj.org/article/0c0473170acb4c4b99c95e471322f0fb
Autor:
Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Yun-Shien Lee, Jang-Hau Lian, Hsi-Lung Hsieh, Chi-Yuan Chen
Publikováno v:
Journal of the Formosan Medical Association, Vol 120, Iss 9, Pp 1695-1705 (2021)
Background/purpose: Palbociclib is an FDA-approved cyclin-dependent kinase (CDK) 4/6 inhibitor that has been clinically proven to be effective in breast cancer. However, its use in oral cancer is not well researched. In this study, we investigated th
Externí odkaz:
https://doaj.org/article/daf17f6fac1b488ba297c9895c342afe
Autor:
Chi-Yuan Chen, Jia-You Fang, Chin-Chuan Chen, Wen-Yu Chuang, Yann-Lii Leu, Shir-Hwa Ueng, Li-Shan Wei, Shu-Fang Cheng, Chuen Hsueh, Tong-Hong Wang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Magnolia officinalis is widely used in Southeast Asian countries for the treatment of fever, headache, diarrhea, and stroke. Magnolol is a phenolic compound extracted from M. officinalis, with proven antibacterial, antioxidant, anti-inflammatory, and
Externí odkaz:
https://doaj.org/article/06c742b05cc0402f956e496450067e22
Autor:
Chi-Yuan Chen, Chin-Chuan Chen, Wen-Yu Chuang, Yann-Lii Leu, Shir-Hwa Ueng, Chuen Hsueh, Chau-Ting Yeh, Tong-Hong Wang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Abnormal histone deacetylase (HDAC) expression is closely related to cancer development and progression. Many HDAC inhibitors have been widely used in cancer treatment; however, severe side effects often limit their clinical application. In this stud
Externí odkaz:
https://doaj.org/article/e01fd86c2b784654b07831d658fb5307
Autor:
Kuo-Yen Huang, Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Hsin-Jung Li, Cai-Ling Jhong, Chi-Yuan Chen
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1271 (2021)
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are approved treatments for non-small-cell lung cancer (NSCLC) patients harboring activating EGFR mutations. The EGFR C797S mutation is one of the known acquired-resistance mut
Externí odkaz:
https://doaj.org/article/51e8c23c27ee4e349820f36017f61f2f
Autor:
Tong-Hong Wang, Yann-Lii Leu, Chin-Chuan Chen, Tzong-Ming Shieh, Jang-Hau Lian, Chi-Yuan Chen
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The extract of the seeds of Psoralea corylifolia Linn. (P. corylifolia) have been shown to display anti-tumor activity. However, the prospects of the active compounds from this plant in the treatment of oral squamous cell carcinoma (OSCC) remains unc
Externí odkaz:
https://doaj.org/article/68355e509d504986b333ebb918090de8
Autor:
Tong‐Hong Wang, Yann‐Lii Leu, Chin‐Chuan Chen, Hsin‐Jung Li, Shuenn‐Chen Yang, Kuo‐Yen Huang, Chi‐Yuan Chen
Publikováno v:
Phytotherapy Research. 36:2116-2126
The extracts from Psoralea corylifolia Linn. (P. corylifolia) seeds have been shown to display antitumor activity. To date, the prospects of this plant and its active compounds in the treatment of non-small-cell lung cancer (NSCLC) have not been thor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a779cf3d238968a4608eb68fd082bfbd
https://doi.org/10.1002/ptr.7432
https://doi.org/10.1002/ptr.7432
Autor:
Tong‐Hong Wang, Kuo‐Yen Huang, Chin‐Chuan Chen, Ya‐Hsuan Chang, Hsuan‐Yu Chen, Chuen Hsueh, Yi‐Tsen Liu, Shuenn‐Chen Yang, Pan‐Chyr Yang, Chi‐Yuan Chen
Publikováno v:
EMBO Molecular Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320688e7528843d1f88101beed69b7aa
https://doi.org/10.15252/emmm.202217014
https://doi.org/10.15252/emmm.202217014