Zobrazeno 1 - 10
of 1 191
pro vyhledávání: '"Chimeric protein"'
Publikováno v:
Electronic Journal of Biotechnology, Vol 71, Iss , Pp 19-27 (2024)
Background: The important challenge to the biotechnology is to find new effective fusion partners that enable to improve solubility, expression, and optimize the subsequent fine purification of the target protein. Results: The most invariant part of
Externí odkaz:
https://doaj.org/article/7f3983c60ba24c1ab65f9f6e49715cb6
Autor:
Ada da Silva Matos, Isabela Ferreira Soares, Rodrigo Nunes Rodrigues-da-Silva, Cinthia Magalhães Rodolphi, Letusa Albrecht, Rafael Amaral Donassolo, Cesar Lopez-Camacho, Ana Paula Dinis Ano Bom, Patrícia Cristina da Costa Neves, Fernando de Paiva Conte, Lilian Rose Pratt-Riccio, Cláudio Tadeu Daniel-Ribeiro, Paulo Renato Rivas Totino, Josué da Costa Lima-Junior
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In the Americas, P. vivax is the predominant causative species of malaria, a debilitating and economically significant disease. Due to the complexity of the malaria parasite life cycle, a vaccine formulation with multiple antigens expressed in variou
Externí odkaz:
https://doaj.org/article/beb207a3a85f4e0ea688e8e6c4a1ea29
Publikováno v:
Vaccines, Vol 12, Iss 7, p 753 (2024)
Although respiratory syncytial virus (RSV) vaccine development initiatives have existed for half a century, no candidate has been approved for application at all ages from neonates to children. Developing an effective and safe RSV vaccine for pediatr
Externí odkaz:
https://doaj.org/article/26bb458594c6450fa4702b9ec0f545f0
Publikováno v:
Novelty in Clinical Medicine, Vol 2, Iss 2, Pp 75-81 (2023)
Background: Niosomes are vesicles, a new drug delivery system, which can be It is used for sustained, controlled as well as targeted delivery of drugs. Niosomes are vesicles, a new drug delivery system, which can be They are used for sustained, contr
Externí odkaz:
https://doaj.org/article/cbc2cbbde8f4418e9d1d8523d4e3a1c9
Autor:
Roberto M. Vidal, David A. Montero, Adriana Bentancor, Carolina Arellano, Alhejandra Alvarez, Cecilia Cundon, Ximena Blanco Crivelli, Felipe Del Canto, Juan C. Salazar, Angel A. Oñate
Publikováno v:
Vaccines, Vol 12, Iss 7, p 726 (2024)
Shiga toxin-producing Escherichia coli (STEC) poses a significant public health risk due to its zoonotic potential and association with severe human diseases, such as hemorrhagic colitis and hemolytic uremic syndrome. Ruminants are recognized as prim
Externí odkaz:
https://doaj.org/article/dac9c5044f5a4f07a28c8b922040c766
Autor:
María Elisa Vázquez, Brenda A. Zabala, Andrea C. Mesías, Lucia Biscari, Cintia D. Kaufman, Andrés Alloatti, Francesco Siano, Gianluca Picariello, Natalia S. Corbalán, Bladimiro A. Lenis, Marta A. Toscano, Cecilia M. Parodi, Cecilia M. Pérez Brandán, Leonardo Acuña
Publikováno v:
Vaccines, Vol 12, Iss 6, p 621 (2024)
Chagas disease, caused by the protozoan Trypanosoma cruzi, remains a major public health challenge affecting millions in Latin America and worldwide. Although significant progress has been made in vector control, no vaccine exists to prevent infectio
Externí odkaz:
https://doaj.org/article/34c0bd56a2614a5baf5bc51216f46402
Autor:
Yadira Lobaina, Rong Chen, Edith Suzarte, Panchao Ai, Alexis Musacchio, Yaqin Lan, Glay Chinea, Changyuan Tan, Ricardo Silva, Gerardo Guillen, Ke Yang, Wen Li, Yasser Perera, Lisset Hermida
Publikováno v:
Vaccines, Vol 12, Iss 6, p 588 (2024)
A chimeric protein, formed by two fragments of the conserved nucleocapsid (N) and S2 proteins from SARS-CoV-2, was obtained as a recombinant construct in Escherichia coli. The N fragment belongs to the C-terminal domain whereas the S2 fragment spans
Externí odkaz:
https://doaj.org/article/431c941993434e4796debcbd54b112fb
Autor:
Farzaneh pourkarimi Fatideh, Majid Esmaelizad, Mohammad Kargar, Majid Tebianian, Farshid Kafilzadeh
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 20, Iss 1, Pp 1-12 (2022)
Highlights • This is first study to present chimeric protein rPvpA-pMGA as a candidate antigen in ELISA. • High-yield 138 mg/L purification of recombinant protein. • rPvpA-pMGA is a reliable immunogenic protein which induced high amount of humo
Externí odkaz:
https://doaj.org/article/5b6b0f11eada4b5bbb0d68e4d21742cd
Autor:
David A. Montero, Richard Garcia-Betancourt, Roberto M. Vidal, Juliana Velasco, Pablo A. Palacios, Daniela Schneider, Carolina Vega, Leonardo Gómez, Hernán Montecinos, Rodrigo Soto-Shara, Ángel Oñate, Leandro J. Carreño
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundShiga toxin-producing Escherichia coli (STEC) is a foodborne pathogen that causes gastrointestinal infections, ranging from acute diarrhea and dysentery to life-threatening diseases such as Hemolytic Uremic Syndrome. Currently, a vaccine to
Externí odkaz:
https://doaj.org/article/026ccd6fd0ec4811a782cfea1d8ab725
Autor:
Asad Murtaza, Nguyen-Thanh Hoa, Do Dieu-Huong, Haroon Afzal, Muhammad Hamza Tariq, Li-Ting Cheng, Yao-Chi Chung
Publikováno v:
Vaccines, Vol 12, Iss 2, p 139 (2024)
Vaccinations can serve as an important preventive measure against the porcine epidemic diarrhea (PED) virus that currently threatens the swine industry. This study focuses on the development of a fusion protein vaccine, FliC99-mCOE, which combines th
Externí odkaz:
https://doaj.org/article/b83a7f73cbdf409187f33970e0ea82ee