Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Chiman, Song"'
Autor:
Elliot H. Lee, Jung-eun Park, Lizaveta Gotina, Young-Eun Han, Ambily Nath Indu Viswanath, Seonguk Yoo, Bongjin Moon, Jin-Young Hwang, Woo Kyu Park, Yoonjeong Cho, Chiman Song, Sun-Joon Min, Eun Mi Hwang, Hyunbeom Lee, Ae Nim Pae, Eun Joo Roh, Soo-Jin Oh
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115139- (2023)
TREK-1 (TWIK-related potassium channel-1) is a subunit of the two-pore domain potassium (K2p) channel and is widely expressed in the brain. TREK-1 knockout mice were shown to have antidepressant-like effects, providing evidence for the channel's pote
Externí odkaz:
https://doaj.org/article/e75576798c434684a9173742b6f0fcf7
Autor:
Hyomin Ahn, Kichul Park, Dongyoung Kim, Sung-Gil Chi, Kee-Hyun Choi, Seo-Jung Han, Chiman Song
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2846 (2023)
Monoamine transporters, including dopamine, norepinephrine, and serotonin transporters (DAT, NET, and SERT, respectively), are important therapeutic targets due to their essential roles in the brain. To overcome the slow action of selective monoamine
Externí odkaz:
https://doaj.org/article/994692cf78634bf1a827887f379e9027
Autor:
Jin-Gyeong Park, Hanul Jeon, Sangchul Shin, Chiman Song, Hyomin Lee, Nak-Kyoon Kim, Eunice EunKyeong Kim, Kwang Yeon Hwang, Bong-Jin Lee, In-Gyun Lee
Publikováno v:
Science Advances. 9
Aurora kinase A (AURKA) performs critical functions in mitosis. Thus, the activity and subcellular localization of AURKA are tightly regulated and depend on diverse factors including interactions with the multiple binding cofactors. How these differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5bcd0be9d0eb4e94f7a262baa686ec7
https://doi.org/10.1126/sciadv.adf8582
https://doi.org/10.1126/sciadv.adf8582
Autor:
Md. Ashrafuzzaman, Su Hyun Ji, Hyomin Ahn, Hwan Won Chung, Daeun Choi, Ju Jin Park, Minji Go, Jung In Pyo, Azam Sharif Mohammed Shafioul, Duck‐Hyung Lee, Sung‐Gil Chi, Chiman Song, Chan Seong Cheong, Seo‐Jung Han
Publikováno v:
Bulletin of the Korean Chemical Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3627cd085334d57611e726f7184a19ad
https://doi.org/10.1002/bkcs.12693
https://doi.org/10.1002/bkcs.12693
Autor:
Yunju Nam, Chan Kim, Junghee Han, SeongShick Ryu, Hanna Cho, Chiman Song, Nam Doo Kim, Namkyoung Kim, Taebo Sim
Publikováno v:
Cancers; Volume 15; Issue 1; Pages: 143
c-KIT is a promising therapeutic target against gastrointestinal stromal tumor (GIST). In order to identify novel c-KIT inhibitors capable of overcoming imatinib resistance, we synthesized 31 novel thiazolo[5,4-b]pyridine derivatives and performed SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8cdc077e43089605d491e4ff37a981
Autor:
Yunju, Nam, Chan, Kim, Junghee, Han, SeongShick, Ryu, Hanna, Cho, Chiman, Song, Nam Doo, Kim, Namkyoung, Kim, Taebo, Sim
Publikováno v:
Cancers. 15(1)
c-KIT is a promising therapeutic target against gastrointestinal stromal tumor (GIST). In order to identify novel c-KIT inhibitors capable of overcoming imatinib resistance, we synthesized 31 novel thiazolo[5,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dce576a2c7a63c9335d44effb5dbd5b
https://pubmed.ncbi.nlm.nih.gov/36612139
https://pubmed.ncbi.nlm.nih.gov/36612139
Autor:
Chiman Song, SeongShick Ryu, Nam Doo Kim, Nam Hoon Kwon, Taebo Sim, Injae Shin, Eunhye Jeon, Ji Won Lee, Youngji Moon, Young Hoon Kim, Hojong Yoon, Sunghoon Kim, Hwan Geun Choi, Hanna Cho
Publikováno v:
Journal of Medicinal Chemistry. 64:11934-11957
Focal adhesion kinase (FAK) is overexpressed in highly invasive and metastatic cancers. To identify novel FAK inhibitors, we designed and synthesized various thieno[3,2-d]pyrimidine derivatives. An intensive structure-activity relationship (SAR) stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5deef0a2082593f2759a2669c42e311
https://doi.org/10.1021/acs.jmedchem.1c00459
https://doi.org/10.1021/acs.jmedchem.1c00459
Autor:
Elliot Lee, Jung-eun Park, Young-Eun Han, Ambily Viswanath, Lizaveta Gotina, Yoonjeong Cho, Bongjin Moon, Jin-Young Hwang, Woo Kyu Park, Seonguk Yoo, Chiman Song, Sun-Joon Min, Eun Mi Hwang, Hyunbeom Lee, Ae Nim Pae, Eun Joo Roh, Soo-Jin Oh
Background and Purpose: TREK-1 (TWIK-related potassium channel-1) is a subunit of the two-pore domain potassium (K2p) channel and is widely expressed in the brain. TREK-1 knockout mice were shown to have antidepressant-like effects, providing evidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4f6bd5cc5b0b74d2e16774a6731d24
https://doi.org/10.22541/au.165831305.52906029/v1
https://doi.org/10.22541/au.165831305.52906029/v1
Publikováno v:
Journal of Cellular Physiology. 235:10037-10050
Transient receptor potential cation channel subfamily M member 7 (TRPM7) composed of an ion channel and a kinase domain regulates triple-negative breast cancer (TNBC) cell migration, invasion, and metastasis, but it does not modulate TNBC proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41922a9b476f3ac6c392e1bdfb0d5805
https://doi.org/10.1002/jcp.29820
https://doi.org/10.1002/jcp.29820
Autor:
In-Gyun Lee, Chiman Song, Seoyeong Yang, Hanul Jeon, Jingyeong Park, Hye-Jin Yoon, Hookang Im, Sung-Min Kang, Hyun-Jong Eun, Bong-Jin Lee
Publikováno v:
Acta crystallographica. Section D, Structural biology. 78(Pt 4)
D-Alanylation of the teichoic acids of the Gram-positive bacterial cell wall plays crucial roles in bacterial physiology and virulence. Deprivation of D-alanine from the teichoic acids of Staphylococcus aureus impairs biofilm and colony formation, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e8a0960efd300df585cf8430481507
https://pubmed.ncbi.nlm.nih.gov/35362466
https://pubmed.ncbi.nlm.nih.gov/35362466