Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chima Matsumoto"'
Autor:
Osamu Ohmori, Kazuko Shimizu, Shinichi Sakata, Yuko Fukunaka, Takahiro Shinkai, Rudi Hwang, Kensuke Utsunomiya, Chima Matsumoto, Yui Naoe, Hiroko Hori, Jun Nakamura
Publikováno v:
NeuroMolecular Medicine. 9:292-297
The underlying pathophysiology of primary polydipsia in schizophrenia (SCZ) is poorly understood. Our previous study, however, suggested that this condition may have a genetic component [Shinkai et al 2003 Am J Med Genet 119B 7-12]. Orexins, also cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f05b43ac964d22903929fc0ea70dab8
https://doi.org/10.1007/s12017-007-8001-2
https://doi.org/10.1007/s12017-007-8001-2
Autor:
Rudi Hwang, Albert H.C. Wong, Gwyneth Zai, Gregory W.H. Wong, Joseph Trakalo, Chima Matsumoto, Matthew B. Lanktree, Takahiro Shinkai, Osamu Ohmori, Fabio Macciardi, James L. Kennedy, Daniel J. Müller, Tricia Sicard, Jun Nakamura, Sajid A. Shaikh, Natalia Potapova, Nicole King, Vincenzo De Luca, Hiroko Hori
Publikováno v:
NeuroMolecular Medicine. 9:169-177
A number of linkage studies have previously implicated the region of chromosome 13q34 in schizophrenia. Chumakov and colleagues (2002) identified a gene complex called G72 (now termed D-amino acid oxidase activator: DAOA)/G30 in this region and perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114a3bbc9aa19288709ce0f496be23ad
https://doi.org/10.1007/bf02685890
https://doi.org/10.1007/bf02685890
Autor:
Yasuhisa Yamada, Nobuhisa Ueda, Chima Matsumoto, Reiji Yoshimura, Osamu Ohmori, Shingo Kakihara, Koji Shinkai, Kyoko Kaji, Makiko Goto, Jun Nakamura
Publikováno v:
International Clinical Psychopharmacology. 20:71-78
In the present study, we examined the relationships between plasma concentrations of risperidone and clinical responses, extrapyramidal symptoms, plasma levels of cotinine and caffeine, or cytochrome (cyp)2D6 genotypes. In addition, we also investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2aafdff97e3841536f21a014f6b3120
https://doi.org/10.1097/00004850-200503000-00002
https://doi.org/10.1097/00004850-200503000-00002
Publikováno v:
Psychiatric Genetics. 14:209-213
OBJECTIVE Recent studies have revealed positive associations between tardive dyskinesia (TD) and genetic polymorphisms of several cytochrome P450 (CYP) subfamilies that are involved in pharmacokinetic process of antipsychotic drugs. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcb3eff507ae40969cc5dd1a3e56955
https://doi.org/10.1097/00041444-200412000-00008
https://doi.org/10.1097/00041444-200412000-00008
Autor:
Gregory W.H. Wong, Osamu Ohmori, Paul D. Arnold, Sajid A. Shaikh, Nicole King, James L. Kennedy, Takahiro Shinkai, Albert H.C. Wong, Gwyneth Zai, Natalia Potapova, Chima Matsumoto, Joseph Trakalo, Rudi Hwang, Jun Nakamura, Hiroko Hori, Vincenzo De Luca
Publikováno v:
Psychiatric Genetics. 14:177-180
Oxidative stress such as free radical-mediated neuronal dysfunction may be involved in the pathophysiology of schizophrenia. The human glutathione peroxidase (GPX1) is a selenium-dependent enzyme, which plays an important role in the detoxification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b240c8771689eba8a93fc35ff8c6f1
https://doi.org/10.1097/00041444-200409000-00012
https://doi.org/10.1097/00041444-200409000-00012
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 27:581-586
Interindividual genetic profile differences related to antipsychotic drug therapy may be determined based on molecular genetic studies of the pathogenesis of schizophrenia and studies of antipsychotic drug responses (therapeutic as well as adverse re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d89a86e02235a3fe2a3f7a37e8f4a1
https://doi.org/10.1016/s0278-5846(03)00082-4
https://doi.org/10.1016/s0278-5846(03)00082-4
Publikováno v:
Psychiatry Research. 118:235-239
NAD(P)H: quinone oxidoreductase (NQO1), an obligate two-electron reductase of quinones, prevents their participation in redox cycling and subsequent generation of reactive oxygen species (ROS). Reduced or negative activity of NQO1 would lead to an ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32101b862d593990e4e26858197955c
https://doi.org/10.1016/s0165-1781(03)00095-7
https://doi.org/10.1016/s0165-1781(03)00095-7
Publikováno v:
Neuroscience Letters. 321:165-168
An increasing amount of evidence suggests a possible implication of oxidative stress in the pathophysiology of schizophrenia. Oxidized low-density lipoproteins (oxLDL) have been reported to be capable of eliciting neurocytotoxicity. On the other hand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d670c1e9c26b2979343a2e5b9bbacc
https://doi.org/10.1016/s0304-3940(02)00049-6
https://doi.org/10.1016/s0304-3940(02)00049-6
Autor:
Osamu Ohmori, Kensuke Utsunomiya, Yui Naoe, Kazuko Shimizu, Jun Nakamura, Takahiro Shinkai, Shinichi Sakata, Hiroko Hori, Rudi Hwang, Chima Matsumoto, Yuko Fukunaka
Publikováno v:
Neuroscience letters. 415(2)
Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that plays an important role in the development and maintenance of adult neurons and is important regulator of synaptic plasticity in human brain. It has been reported that there are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00441b9b29a9108d50a134f4b7867fa7
https://pubmed.ncbi.nlm.nih.gov/17267117
https://pubmed.ncbi.nlm.nih.gov/17267117
Autor:
Vincenzo De Luca, Takahiro Shinkai, Jun Nakamura, Rudi Hwang, Hiroko Hori, Osamu Ohmori, Chima Matsumoto, James L. Kennedy
Publikováno v:
Neuromolecular medicine. 8(3)
The underlying pathophysiology of polydipsia in schizophernia is poorly understood. Several studies, however, have suggested that there might be a genetic predisposition to polydipsia. In the present study, using a case-control sample that is indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5fefbd36e4ec76b51cc67adb89972c
https://pubmed.ncbi.nlm.nih.gov/16775389
https://pubmed.ncbi.nlm.nih.gov/16775389