Zobrazeno 1 - 10
of 783
pro vyhledávání: '"Chim C, Lang"'
Autor:
Mon Myat Oo, Chuang Gao, Christian Cole, Yoran Hummel, Magalie Guignard‐Duff, Emily Jefferson, James Hare, Adriaan A. Voors, Rudolf A. deBoer, Carolyn S.P. Lam, Ify R. Mordi, Jasper Tromp, Chim C. Lang
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 2769-2777 (2024)
Abstract Aims Electronic health records (EHR) linked to Digital Imaging and Communications in Medicine (DICOM), biological specimens, and deep learning (DL) algorithms could potentially improve patient care through automated case detection and survei
Externí odkaz:
https://doaj.org/article/2870b87907db4df9839419fb8ce23508
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background and Aims Sodium-glucose co-transporter 2 (SGLT2) inhibitors have beneficial effects in heart failure (HF), including reverse remodelling, but the mechanisms by which these benefits are conferred are unclear. Inflammation is implic
Externí odkaz:
https://doaj.org/article/33a82ecb2bdf4a93a0f66ac54313e311
Autor:
Vishal Musale, Colin E. Murdoch, Ayman K. Banah, Annie Hasib, Chandani K. Hennayake, Bo Dong, Chim C. Lang, David H. Wasserman, Li Kang
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101970- (2024)
Objective: Obesity increases deposition of extracellular matrix (ECM) components of cardiac tissue. Since obesity aggregates with insulin resistance and heart disease, it is imperative to determine whether the increased ECM deposition contributes to
Externí odkaz:
https://doaj.org/article/a263f7a9365d413da8217d61d8a513a5
Autor:
Eerde H. Weening, Ali A. Al-Mubarak, Martin M. Dokter, Kenneth Dickstein, Chim C. Lang, Leong L. Ng, Marco Metra, Dirk J. van Veldhuisen, Daan J. Touw, Rudolf A. de Boer, Ron T. Gansevoort, Adriaan A. Voors, Stephan J. L. Bakker, Peter van der Meer, Nils Bomer
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Serum selenium levels have been associated with the incidence of heart failure (HF) and signs of the metabolic syndrome. In addition, notable differences have been reported between males and females in food intake and micronutrien
Externí odkaz:
https://doaj.org/article/0e391b3e786140c3859e2ca8f1016731
Autor:
Valentina Bracun, Bart vanEssen, Adriaan A. Voors, Dirk J. vanVeldhuisen, Kenneth Dickstein, Faiez Zannad, Marco Metra, Stefan Anker, Nilesh J. Samani, Piotr Ponikowski, Gerasimos Filippatos, John G.F. Cleland, Chim C. Lang, Leong L. Ng, Canxia Shi, Sanne deWit, Joseph Pierre Aboumsallem, Wouter C. Meijers, IJsbrand T. Klip, Peter van derMeer, Rudolf A. deBoer
Publikováno v:
ESC Heart Failure, Vol 9, Iss 6, Pp 4167-4176 (2022)
Abstract Aims Insulin like growth factor binding protein 7 (IGFBP7) is a marker of senescence secretome and a novel biomarker in patients with heart failure (HF). We evaluated the prognostic value of IGFBP7 in patients with heart failure and examined
Externí odkaz:
https://doaj.org/article/331e2838fd9f4900aa0005a68a32db63
Autor:
Calum Forteath, Ify Mordi, Raid Nisr, Erika J. Gutierrez-Lara, Noor Alqurashi, Iain R. Phair, Amy R. Cameron, Craig Beall, Ibrahim Bahr, Mohapradeep Mohan, Aaron K.F. Wong, Adel Dihoum, Anwar Mohammad, Colin N.A. Palmer, Douglas Lamont, Kei Sakamoto, Benoit Viollet, Marc Foretz, Chim C. Lang, Graham Rena
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101750- (2023)
Objective: Unexplained changes in regulation of branched chain amino acids (BCAA) during diabetes therapy with metformin have been known for years. Here we have investigated mechanisms underlying this effect. Methods: We used cellular approaches, inc
Externí odkaz:
https://doaj.org/article/6034f1d72e63418cb69e689338644a8d
Autor:
Zhen Hui Peh, Adel Dihoum, Dana Hutton, J. Simon C. Arthur, Graham Rena, Faisel Khan, Chim C. Lang, Ify R. Mordi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Heart failure with preserved ejection fraction (HFpEF) accounts for around half of all cases of heart failure and may become the dominant type of heart failure in the near future. Unlike HF with reduced ejection fraction there are few evidence-based
Externí odkaz:
https://doaj.org/article/d0e1aa5fca884514b08614539715dcd2
Autor:
Gianluigi Savarese, Alicia Uijl, Wouter Ouwerkerk, Jasper Tromp, Stefan D. Anker, Kenneth Dickstein, Camilla Hage, Carolyn S.P. Lam, Chim C. Lang, Marco Metra, Leong L. Ng, Nicola Orsini, Nilesh J. Samani, Dirk J. vanVeldhuisen, John G.F. Cleland, Adriaan A. Voors, Lars H. Lund
Publikováno v:
ESC Heart Failure, Vol 9, Iss 4, Pp 2107-2118 (2022)
Abstract Aims No biomarker has achieved widespread acceptance as a surrogate endpoint for early‐phase heart failure (HF) trials. We assessed whether changes over time in a panel of plasma biomarkers were associated with subsequent morbidity/mortali
Externí odkaz:
https://doaj.org/article/2a10c1e7c4934e62b1a56f214be0a7f7
Autor:
Koen W. Streng, Hans L. Hillege, Jozine M. terMaaten, Dirk J. vanVeldhuisen, Kenneth Dickstein, Leong L. Ng, Nilesh J. Samani, Marco Metra, Piotr Ponikowski, John G. Cleland, Stefan D. Anker, Simon P.R. Romaine, Kevin Damman, Peter van derMeer, Chim C. Lang, Adriaan A. Voors
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1762-1770 (2022)
Abstract Background A higher protein intake has been associated with a higher muscle mass and lower mortality rates in the general population, but data about protein intake and survival in patients with heart failure (HF) are lacking. Methods We stud
Externí odkaz:
https://doaj.org/article/09abab01211642089de26c745d0136e0
Autor:
Seonaidh Cotton, Graham Devereux, Hassan Abbas, Andrew Briggs, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Dana Dawson, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Chim C. Lang, Amanda J. Lee, Graeme MacLennan, William MacNee, Kirsty McCormack, Nicola McMeekin, Nicholas L. Mills, Alyn Morice, John Norrie, Mark C. Petrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Brian J. Lipworth
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity, mortality and healthcare costs. Beta blockers are well-established drugs widely used to treat cardiovascular conditions. Observational studies
Externí odkaz:
https://doaj.org/article/40c9bddce31b4656a48105e69d45e3c0