Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chimène Charbel"'
Autor:
Delphine M Béziau, Fanny Toussaint, Alexandre Blanchette, Nour R Dayeh, Chimène Charbel, Jean-Claude Tardif, Jocelyn Dupuis, Jonathan Ledoux
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123769 (2015)
Phospholipase C (PLC) comprises a superfamily of enzymes that play a key role in a wide array of intracellular signalling pathways, including protein kinase C and intracellular calcium. Thirteen different mammalian PLC isoforms have been identified a
Externí odkaz:
https://doaj.org/article/108cee6842694178a0602809589d023d
Publikováno v:
Cell Calcium. 58:275-285
Localized endothelial Ca 2+ signalling, such as Ca 2+ pulsars, can modulate the contractile state of the underlying vascular smooth muscle cell through specific endothelial targets. In addition to K Ca 3.1 as a target, Ca 2+ pulsars, an IP 3 R-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c44e8a74399f58a13192a39a3001c3f
https://doi.org/10.1016/j.ceca.2015.06.005
https://doi.org/10.1016/j.ceca.2015.06.005
Publikováno v:
American Journal of Physiology-Cell Physiology. 303:C236-C243
Ca2+ signals are commonly measured using fluorescent Ca2+ indicators and microscopy techniques, but manual analysis of Ca2+ measurements is time consuming and subject to bias. Automated region of interest (ROI) detection algorithms have been employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb8985de241fc50e3a27b1ba9328eb3
https://doi.org/10.1152/ajpcell.00016.2012
https://doi.org/10.1152/ajpcell.00016.2012
Publikováno v:
American journal of physiology. Cell physiology. 311(3)
First characterized in neuronal tissues, the multifunctional calcium/calmodulin-dependent protein kinase II (CaMKII) is a key signaling component in several mammalian biological systems. Its unique capacity to integrate various Ca2+signals into diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b2bbea093be5fc39097c093d7f5058
https://pubmed.ncbi.nlm.nih.gov/27306369
https://pubmed.ncbi.nlm.nih.gov/27306369
Autor:
Jonathan Ledoux, Delphine Béziau, Fanny Toussaint, Gaétan Mayer, Alexandre Blanchette, Chimène Charbel
Publikováno v:
The FASEB Journal. 29
Calcium (Ca2+) homeostasis is critical to endothelial function. Indeed, localized endothelial Ca2+ signals, such as Ca2+ pulsars - restricted IP3R-dependent Ca2+ releases within myoendothelial proj...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5640b4d330a56c2a250e158f66319294
https://doi.org/10.1096/fasebj.29.1_supplement.956.2
https://doi.org/10.1096/fasebj.29.1_supplement.956.2
Publikováno v:
Cell calcium. 58(3)
Localized endothelial Ca(2+) signalling, such as Ca(2+) pulsars, can modulate the contractile state of the underlying vascular smooth muscle cell through specific endothelial targets. In addition to K(Ca)3.1 as a target, Ca(2+) pulsars, an IP3R-depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8ab23e2b6c9df71e204e8b3459c9f1a
https://pubmed.ncbi.nlm.nih.gov/26100947
https://pubmed.ncbi.nlm.nih.gov/26100947
Autor:
Philippe Comtois, Fanny Toussaint, Marc-Antoine Gillis, Alexandre Blanchette, Chimène Charbel, Jonathan Ledoux
Publikováno v:
The FASEB Journal. 28
Angiotensin II-induced arterial hypertension (AngII-AH) is associated with an endothelial dysfunction characterized by a Ca2+ dyshomeostasis. Alteration of the delicate balance between reactive oxy...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1446f70815a2ff136715db1dc975988e
https://doi.org/10.1096/fasebj.28.1_supplement.851.6
https://doi.org/10.1096/fasebj.28.1_supplement.851.6
Autor:
Delphine Béziau, Nour Daya, Alexandre Blanchette, Chimène Charbel, Jonathan Ledoux, Fanny Toussaint
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a33fad4d773a5827d0270c72aa4edc
https://doi.org/10.1096/fasebj.28.1_supplement.1075.2
https://doi.org/10.1096/fasebj.28.1_supplement.1075.2
Publikováno v:
The FASEB Journal. 28
Endothelial Ca2+ pulsar consists in a spontaneous Ca2+ release from IP3R localized within myoendothelial projections (MEP). We recently showed CaMKII activation by Ca2+ pulsars, thus modulating endothelial function through NO production. Moreover, Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e1ee509a3cc63c37a32cbc8e89082a5
https://doi.org/10.1096/fasebj.28.1_supplement.1075.1
https://doi.org/10.1096/fasebj.28.1_supplement.1075.1
Autor:
Gaétan Mayer, Chimène Charbel, Jonathan Ledoux, Fanny Toussaint, Alexandre Blanchette, Delphine Béziau
Publikováno v:
The FASEB Journal. 28
Calcium homeostasis is the crux of endothelial function and the regulation of vascular tone. Endothelial Ca2+ is thus highly dynamic and finely tuned. Amongst Ca2+ dynamics, Ca2+ pulsars are sponta...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a88fac2a4fcc2e2159d0dec2662e36bf
https://doi.org/10.1096/fasebj.28.1_supplement.1075.3
https://doi.org/10.1096/fasebj.28.1_supplement.1075.3