Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics.

Autor: Smeal SW; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Mokashi CS; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; current address Altos Labs, Redwood City, CA, 94065, USA., Kim AH; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Chiknas PM; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Lee REC; Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for Systems Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 01. Date of Electronic Publication: 2024 Oct 01.

On-Chip Reconstitution of Uniformly Shear-Sensing 3D Matrix-embedded Multicellular Blood Microvessel.

Autor: Vo Q; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Carlson KA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA., Chiknas PM; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Brocker CN; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., DaSilva L; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Clark E; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Park SK; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Ajiboye AS; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Wier EM; Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA., Benam KH; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Publikováno v: Advanced functional materials [Adv Funct Mater] 2024 Mar 04; Vol. 34 (10). Date of Electronic Publication: 2023 Aug 07.