Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chike Osude"'
Autor:
Chike Osude, Leo Lin, Meet Patel, Adam Eckburg, Joseph Berei, Adijan Kuckovic, Namrata Dube, Aayush Rastogi, Shruti Gautam, Thomas J. Smith, Shylendra B. Sreenivassappa, Neelu Puri
Publikováno v:
Cells, Vol 11, Iss 10, p 1694 (2022)
NSCLC treatment includes targeting of EGFR with tyrosine kinase inhibitors (TKIs) such as Erlotinib; however, resistance to TKIs is commonly acquired through T790M EGFR mutations or overexpression of vascular endothelial growth factor receptor-2 (VEG
Externí odkaz:
https://doaj.org/article/aa83e90141d14f91a0783e80526c33ad
Autor:
Zachary Schrank, Nabiha Khan, Chike Osude, Sanjana Singh, Rachel J. Miller, Collin Merrick, Alexander Mabel, Adijan Kuckovic, Neelu Puri
Publikováno v:
Molecules, Vol 23, Iss 9, p 2267 (2018)
Telomeres and telomerase have become attractive targets for the development of anticancer therapeutics due to their involvement in cancer cell immortality. Currently, several therapeutics have been developed that directly target telomerase and telome
Externí odkaz:
https://doaj.org/article/f9f9853b56c64e389c88ba22c4a28964
Autor:
Zachary Schrank, Gagan Chhabra, Leo Lin, Tsatsral Iderzorig, Chike Osude, Nabiha Khan, Adijan Kuckovic, Sanjana Singh, Rachel J. Miller, Neelu Puri
Publikováno v:
Cancers, Vol 10, Iss 7, p 224 (2018)
Lung cancer is treated with many conventional therapies, such as surgery, radiation, and chemotherapy. However, these therapies have multiple undesirable side effects. To bypass the side effects elicited by these conventional treatments, molecularly-
Externí odkaz:
https://doaj.org/article/044ff804b28a4edb88fde80d1eece0b5
Autor:
Joseph Kellen, Sanjana Singh, James A. Woodman, Neelu Puri, Christian Garcia, Chike Osude, Tsatsral Iderzorig
Publikováno v:
Biochemical and Biophysical Research Communications. 496:770-777
In the United States, lung cancer is the second most common cancer in men and women. In 2017, 222,500 new cases and 155,870 deaths from lung cancer are estimated to have occurred. A tyrosine kinase receptor, epidermal growth factor receptor (EGFR) is
Autor:
Neelu Puri, Collin Merrick, Chike Osude, Rachel J. Miller, Sanjana Singh, Nabiha Khan, Adijan Kuckovic, Alexander Mabel, Zachary Schrank
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 9, p 2267 (2018)
Molecules, Vol 23, Iss 9, p 2267 (2018)
Telomeres and telomerase have become attractive targets for the development of anticancer therapeutics due to their involvement in cancer cell immortality. Currently, several therapeutics have been developed that directly target telomerase and telome
Publikováno v:
Cancer Research. 79:2965-2965
T-oligo, a guanine-rich oligonucleotide (GRO) homologous to the 3′ telomeric overhang, has been shown to elicit potent DNA-damage responses (DDRs) in numerous cancer cell lines. However, the detailed molecular mechanism by which T-oligo induces the
Publikováno v:
Cancer Research. 79:189-189
The treatment paradigm for late stage non-small cell lung carcinoma (NSCLC) has shifted towards molecular targeted therapy like epidermal growth factor receptor (EGFR). Tyrosine kinase inhibitors (TKIs) against EGFR have proven to be effective; howev
Publikováno v:
Cancer Research. 78:2595-2595
The treatment paradigm for late stage non-small cell lung carcinoma (NSCLC) has shifted towards molecular targeted therapy like epidermal growth factor receptor (EGFR), one of the most studied targets. Tyrosine kinase inhibitors (TKIs) against EGFR h
Autor:
Zachary D Schrank, Joseph Kellen, Nabiha Khan, Gagan Chhabra, Neelu Puri, Sanjana Singh, Chike Osude
Publikováno v:
Cancer Research. 78:1469-1469
T-oligo, a guanine-rich oligonucleotide (GRO) homologous to the 3′ overhang of telomeres, elicits potent DNA-damage responses (DDRs) in cancer cells. However, the detailed molecular mechanism of T-oligo in cancer cells remains elusive. Recent studi