Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chikara Komuro"'
Publikováno v:
Bulletin of the Chemical Society of Japan. 54:1834-1837
Treatment of tetrakis(N-benzyloxycarbonyl)-6″-O-tritylkanamycin A with sodium hydride in N,N-dimethyl-formamide, followed by chromatography, afforded 4′,6′ : 3″,4″-, and 4′,6′ : 2″,3″-bis(cyclic carbamate) and 3″,4″-and 2″,3
Autor:
Hiroshi Yamanaka, Shuji Kurashige, Yuh-Ichiro Ichikawa, Takao Sakamoto, Chikara Komuro, Hiroshi Miyazaki, Akira Shiozawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 32:2522-2529
5-Methyl-(4a), 7-methyl-(4b), and 8-methyl-5, 6, 7, 8-tetrahydro-1, 6-naphthyridine (4c) were synthesized by chemical modification of pyridine derivatives. On the other hand, the synthesis of the compounds (20b, c) having a methyl group in the aromat
Publikováno v:
The Journal of Antibiotics. 34:1-4
Fourteen patients suffering from female genital organ infections including mastitis and urinary tract infections were treated with cefoperazone (CPZ). CPZ was administered intravenously or by drip infusion at a dose of 2.0-4.0 g/day for 3-7 days. Cli
Autor:
Yuh-Ichiro Ichikawa, Chikara Komuro, Michio Ishikawa, Hiroshi Yamanaka, Takao Sakamoto, Hiroshi Miyazaki, Yasuhiko Furuta, Shuji Kurashige, Akira Shiozawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 32:3981-3993
Autor:
Chikara Komuro, Masaji Takahashi, Dennis C. Shrieve, Mitsuyuki Abe, Takehiro Nishidai, Y. Dodo, Yuta Shibamoto, Koji Ono
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 12:1843-1847
Large radiosensitization of C3H/He mouse mammary tumors was obtained with the combination of a non-protein sulfhydryl (NPSH) depletor, diethyl maleate (DEM), and misonidazole (MISO), compared with MISO alone over a range of MISO dose. The difference
Publikováno v:
Chemistry Letters. 12:1471-1474
Remarkable promation of the hydroxylation of thimine to give thimine glycol with almost complete depression of side reactions by 2,2,6,6-tetramethylpiperidine-1-oxyl (TMPO·) derivatives was observed in the γ-radiolyses of the N2- and N2O-saturated
Publikováno v:
Journal of Radiation Research. 26:404-410
The inhibitory effect of N6-butyrylcordycepin (7904), one of purine nucleoside analogues, on potentially lethal damage repair (PLDR) in vivo was tested using two experimental tumors, EMT6 sarcoma and SCCVII carcinoma, by an in vivo-in vitro assay. Th
Autor:
Hiroshi Yamanaka, Michio Ishikawa, Akira Shiozawa, Yuh-Ichiro Ichikawa, Chikara Komuro, Takao Sakamoto, Hiroshi Miyazaki, Shuji Kurashige, Gen'ichi Idzu
Publikováno v:
Chemical and Pharmaceutical Bulletin. 32:553-563
A series of 2-(2-aminoethyl) pyridines derived by the modification of the amine moiety in betahistine, 2-(2-methylaminoethyl) pyridine, was synthesized and evaluated for antivertigo action in terms of inhibitory activity against spontaneous nystagmus
Autor:
Yuhichiro Ichikawa, Takao Sakamoto, Yoshiya Kogo, Hiroshi Yamanaka, Michio Ishikawa, Chikara Komuro, Akira Shiozawa, Shuji Kurashige, Hiroshi Miyazaki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:5332-5340
The quantitative structure-activity relationships (QSAR) between the molecular structures and antivertigo activities of 6-[2-(4-aryl-1-piperazinyl) ethyl]-5, 6, 7, 8-tetrahydro-1, 6-naphthyridines were investigated. The effects of the ortho-, meta-,
Autor:
Yuh-Ichiro Ichikawa, Shuji Kurashige, Takao Sakamoto, Gen'ichi Idzu, Hiroshi Yamanaka, Akira Shiozawa, Hiroshi Miyazaki, Michio Ishikawa, Chikara Komuro
Publikováno v:
Chemischer Informationsdienst. 15
A series of 2-(2-aminoethyl) pyridines derived by the modification of the amine moiety in betahistine, 2-(2-methylaminoethyl) pyridine, was synthesized and evaluated for antivertigo action in terms of inhibitory activity against spontaneous nystagmus