Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chikara Komiya"'
Autor:
Yoshihiro Niitsu, Chikara Komiya, Akira Takeuchi, Kazunari Hara, Masato Horino, Jun Aoki, Rei Okazaki, Masanori Murakami, Kazutaka Tsujimoto, Kenji Ikeda, Tetsuya Yamada
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284989 (2023)
Adipose-derived stem cells are expected to be applied to regenerative medicine for various incurable diseases including liver cirrhosis. Although microRNAs contained in extracellular vesicles (EV-miRNAs) have been implicated in their regenerative eff
Externí odkaz:
https://doaj.org/article/aa77b7340e274e32a48cd858576c6281
Autor:
Kazunari Hara, Masanori Murakami, Yoshihiro Niitsu, Akira Takeuchi, Masato Horino, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Kenji Ikeda, Mika Tsuiki, Akiyo Tanabe, Toshihiro Tanaka, Minato Yokoyama, Yasuhisa Fujii, Mitsuhide Naruse, Tetsuya Yamada
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectivePrimary bilateral macronodular adrenal hyperplasia (PBMAH), a rare cause of Cushing syndrome, is often diagnosed as a bilateral adrenal incidentaloma with subclinical cortisol production. Circulating microRNAs (miRNAs) are a characteristic o
Externí odkaz:
https://doaj.org/article/33baf986c4bf4b1eb5d34a9d2a29c4ba
Autor:
Kumiko Shiba, Kyoichiro Tsuchiya, Chikara Komiya, Yasutaka Miyachi, Kentaro Mori, Noriko Shimazu, Shinobu Yamaguchi, Naomi Ogasawara, Makoto Katoh, Michiko Itoh, Takayoshi Suganami, Yoshihiro Ogawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Sodium glucose cotransporter 2 (SGLT2) inhibitors, an antidiabetic drug, promotes urinary excretion of glucose by blocking its reabsorption in the renal proximal tubules. It is unclear whether SGLT2 inhibition could attenuate nonalcoholic st
Externí odkaz:
https://doaj.org/article/f40c5869250d4118846a58308f7da1f5
Autor:
Yasutaka Miyachi, Kyoichiro Tsuchiya, Chikara Komiya, Kumiko Shiba, Noriko Shimazu, Shinobu Yamaguchi, Michiyo Deushi, Mizuko Osaka, Kouji Inoue, Yuta Sato, Sayaka Matsumoto, Junichi Kikuta, Kenjiro Wake, Masayuki Yoshida, Masaru Ishii, Yoshihiro Ogawa
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2766-2779 (2017)
Obesity promotes infiltration of inflammatory cells into various tissues, leading to parenchymal and stromal cell interaction and development of cellular and organ dysfunction. Liver sinusoidal endothelial cells (LSECs) are the first cells that conta
Externí odkaz:
https://doaj.org/article/e33dfdfd143c4d5699fe6ff694e6f159
Autor:
Chikara Komiya, Kyoichiro Tsuchiya, Kumiko Shiba, Yasutaka Miyachi, Shunsaku Furuke, Noriko Shimazu, Shinobu Yamaguchi, Kazuo Kanno, Yoshihiro Ogawa
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151511 (2016)
Type 2 diabetes mellitus (T2DM) is associated with a high incidence of non-alcoholic fatty liver disease (NAFLD) related to obesity and insulin resistance. Currently, medical interventions for NAFLD have focused on diet control and exercise to reduce
Externí odkaz:
https://doaj.org/article/d9fd0a9ca395419490df61270b087009
Autor:
Yujiro Nakano, Masanori Murakami, Kazunari Hara, Tatsuya Fukuda, Masato Horino, Akira Takeuchi, Yoshihiro Niitsu, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Minato Yokoyama, Kenji Ikeda, Takanobu Yoshimoto, Yasuhisa Fujii, Tetsuya Yamada
Publikováno v:
Clinical Endocrinology. 98:323-331
Primary aldosteronism (PA) is a major cause of secondary hypertension and is associated with chronic renal injury. The glomerular filtration rate (GFR) in PA rapidly decreases after the removal of glomerular hyperfiltration due to aldosterone excess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f50447374bc2bafa91fab264021117
https://doi.org/10.1111/cen.14849
https://doi.org/10.1111/cen.14849
Autor:
Masanori Murakami, Kazunari Hara, Kenji Ikeda, Masato Horino, Rei Okazaki, Yoshihiro Niitsu, Akira Takeuchi, Jun Aoki, Kumiko Shiba, Kazutaka Tsujimoto, Chikara Komiya, Yuki Nakamura, Morito Kurata, Takumi Akashi, Yasuhisa Fujii, Tetsuya Yamada
Publikováno v:
Hypertension (0194911X); Feb2024, Vol. 81 Issue 2, p361-371, 11p
Autor:
Yujiro Nakano, Kumiko Shiba, Koh-ichiro Yoshiura, Kenji Ikeda, Kazutaka Tsujimoto, Yoshihiro Ogawa, Hitomi Shimizu, Hiroyuki Mishima, Chikara Komiya, Sumito Dateki, Tetsuya Yamada, Kenichi Kashimada
Publikováno v:
Endocrine Journal. 67:1099-1105
Sitosterolemia is caused by homozygous or compound heterozygous gene mutations in either ATP-binding cassette subfamily G member 5 (ABCG5) or 8 (ABCG8). Since ABCG5 and ABCG8 play pivotal roles in the excretion of neutral sterols into feces and bile,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7504343ab01e15885cba7ed78c296dab
https://doi.org/10.1507/endocrj.ej20-0044
https://doi.org/10.1507/endocrj.ej20-0044
Autor:
Yoshihiro Ogawa, Takanobu Yoshimoto, Kazutaka Tsujimoto, Takato Takeuchi, Tatsuya Fukuda, Tetsuya Yamada, Masahiro Asakawa, Ryotaro Bouchi, Chikara Komiya, Kumiko Shiba
Publikováno v:
Diabetic Medicine. 37:105-113
AIM To evaluate the association between sarcopenic obesity and the decline in estimated GFR in people with type 2 diabetes. METHODS We enrolled 745 people with type 2 diabetes (mean age 64.6 years, 53.6% men). Body composition was evaluated using dua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d85397927268ad5239720a10761e98
https://doi.org/10.1111/dme.14153
https://doi.org/10.1111/dme.14153
Autor:
Kentaro Mori, Yoshihiro Ogawa, Naomi Ogasawara, Chikara Komiya, Kyoichiro Tsuchiya, Kumiko Shiba, Yasutaka Miyachi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
The adipose tissue includes various stromal cells, such as preadipocytes, endothelial cells, fibroblasts, and immune cells, which are involved in adipose tissue functions. We previously reported that, in obese mice, the sodium–glucose cotransporter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d742e4292266ac824121aeb0c260db
http://link.springer.com/article/10.1038/s41598-018-34305-x
http://link.springer.com/article/10.1038/s41598-018-34305-x