Výsledky vyhledávání - "Chikara Kadota"

Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cells during inflammation

Autor: Takafumi Yuki, Mohammad Azharul Karim Rumi, Shunji Ishihara, Yoshikazu Kinoshita, Monowar Aziz, Chikara Kadota, Naoki Oshima, Yuji Amano, Yoshiyuki Mishima, Ichiro Moriyama

Publikováno v: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 162(2):348-361

Summary Single immunoglobulin (Ig) interleukin-1R-related molecule (SIGIRR) is an Ig-like membrane protein critical for negative regulation of Toll-like receptor (TLR)-4-mediated signalling. We investigated SIGIRR expression and its regulation mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1accc89ed715c700c5625ccc16b517cc
http://ir.lib.shimane-u.ac.jp/53962

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A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation

Autor: Yoshikazu Kinoshita, Naoki Oshima, Mohammad Azharul Karim Rumi, Yuji Amano, Ichiro Moriyama, Monowar Aziz, Chikara Kadota, Shunji Ishihara, Yoshiyuki Mishima, Norihisa Ishimura

Publikováno v: Clinical and Experimental Immunology. 159:185-198

Summary Several negative regulatory mechanisms control Toll-like receptor (TLR)-mediated inflammatory responses and restore immune system balance, including the zinc-finger protein A20, a negative regulator of TLR signalling that inhibits nuclear fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af040907ba3b7c275adb8a2be41ca4c1
https://doi.org/10.1111/j.1365-2249.2009.04048.x

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Alterations of peripheral blood CD5+B cells in inflammatory bowel disease

Autor: Monowar Aziz, Yoshikazu Kinoshita, Yoshiyuki Mishima, Naoki Oshima, Yuji Amano, Yong-Yu Li, Ichiro Moriyama, Aya Otani, Chikara Kadota, Shunji Ishihara

Publikováno v: Scandinavian Journal of Gastroenterology. 44:172-179

CD5(+) B cells comprise a unique subset of B cells that modulates innate as well as autoimmune systems. The aim of this study was to investigate alterations of the circulating CD5(+) B-cell subset in patients with inflammatory bowel disease (IBD) by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dad18772962e7c44c0d012a6d51c0e4
https://doi.org/10.1080/00365520802433223

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A Japanese case of eosinophilic esophagitis

Autor: Koichiro Furuta, Kentaro Kowari, Hideaki Kazumori, Kenji Furuta, Tatsuya Miyake, Yuko Mishima, Yasunori Kadowaki, Chikara Kadota, Yoshikazu Kinoshita, Shunji Ishihara, Kenji Koshino, Yuji Amano, Kyoichi Adachi, Masaaki Honda, Hiroshi Imaoka, Shuichi Sato

Publikováno v: Journal of Gastroenterology. 41:706-710

Eosinophilic esophagitis (EE) is a rarely diagnosed condition involving eosinophilic infiltration of the esophageal mucosa. Here we present a case of EE in a 69-year-old Japanese man, who presented with abdominal pain, appetite loss, and a history of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71668a632d022f61e1aff5f35f07c1f
https://doi.org/10.1007/s00535-006-1827-9

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Significance of liver biopsy for the evaluation of methotrexate-induced liver damage in patients with rheumatoid arthritis

Autor: Tatsuya, Osuga, Yoshihiro, Ikura, Chikara, Kadota, Seiichi, Hirano, Yasuhiro, Iwai, Takanobu, Hayakumo

Publikováno v: International journal of clinical and experimental pathology. 8(2)

It is well recognized that long-term administration of methotrexate (MTX) in patients with rheumatoid arthritis (RA) can induce liver fibrosis via a steatohepatitis-like inflammatory process. Several non-invasive tests have been investigated as alter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79a5e9404a41c5af6d071fb950b639a6
https://pubmed.ncbi.nlm.nih.gov/25973089

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[A case of multiple skin metastases from cancer of the descending colon responding to FOLFIRI/cetuximab therapy]

Autor: Tomohiro, Kadota, Tatsuya, Osuga, Hirofumi, Ogawa, Motoya, Kitami, Megumi, Ishimura, Yasuhiro, Shigaki, Eishin, Nakajima, Shuji, Nakata, Chikara, Kadota, Seiichi, Hirano, Yoshihiro, Ikura, Yasuhiro, Iwai, Takuro, Yoshikawa, Nozomu, Ueno, Takao, Tamura

Publikováno v: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 111(1)

A 64-year-old woman presented to our hospital with subcutaneous tumors in the right thoracic region. After undergoing a thorough medical evaluation, she was diagnosed with multiple skin metastases arising from cancer of the descending colon. Surgical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac8115cec211b62e26d386db17860307
https://pubmed.ncbi.nlm.nih.gov/24390266

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Decoy oligodeoxynucleotide targeting activator protein-1 (AP-1) attenuates intestinal inflammation in murine experimental colitis

Autor: Yoshikazu Kinoshita, M Azharul Karim Rumi, Ichiro Moriyama, Yasunori Kadowaki, Chikara Kadota, Yoshiyuki Mishima, Naoki Oshima, Monowar Aziz, Yuji Amano, Shunji Ishihara

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 88(6)

Various therapies are used for inflammatory bowel diseases (IBD), though none seem to be extremely effective. AP-1 is a major transcription factor that upregulates genes involved in immune and proinflammatory responses. We investigated decoy oligodeo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765b7ac5b6a3d89dae145be59705dcd2
https://pubmed.ncbi.nlm.nih.gov/18458670

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Prolactin induces MFG-E8 production in macrophages via transcription factor C/EBPbeta-dependent pathway

Autor: Ichiro Moriyama, Yasunori Kadowaki, Mohammad Azharul Karim Rumi, Shunji Ishihara, Yong-Yu Li, Akihiko Oka, Naoki Oshima, Yuji Amano, Norihisa Ishimura, Aya Otani, Md. M. Aziz, Yoshikazu Kinoshita, Yoshiyuki Mishima, Chikara Kadota, Farzana Binte Rahman

Publikováno v: Apoptosis : an international journal on programmed cell death. 13(5)

The lactogenic hormone prolactin (PRL) regulates milk protein gene expression in mammary glands. To maintain homeostatic balance in the body, milk fat globule epidermal growth factor 8 (MFG-E8) is vital for phagocytic clearance of apoptotic cells. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f572d80f4612758f0e62471582a53d3a
https://pubmed.ncbi.nlm.nih.gov/18392683

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