Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Chikara, Hirono"'
Publikováno v:
The Journal of Physiological Sciences. 66:477-490
Intracellular pH (pHi) regulation fundamentally participates in maintaining HCO3- release from HCO3--secreting epithelia. We used parotid intralobular ducts loaded with BCECF to investigate the contributions of a carbonic anhydrase (CA), anion channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665c0625f493db93b687fd01abfef4f2
https://doi.org/10.1007/s12576-016-0443-6
https://doi.org/10.1007/s12576-016-0443-6
Publikováno v:
European journal of oral sciences. 126(3)
Cholinergic agonists evoke elevations of the cytoplasmic free-calcium concentration ([Ca2+ ]i ) to stimulate fluid secretion in salivary glands. Salivary flow rates are significantly reduced in diabetic patients. However, it remains elusive how saliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0858e785ac0c9da3ff3e87d9cc80dbf5
https://pubmed.ncbi.nlm.nih.gov/29676804
https://pubmed.ncbi.nlm.nih.gov/29676804
Autor:
Hiroshi Inoue, Nobuyuki Kamata, Chikara Hirono, Shinichi Fujimoto, Kei Tobiume, Mitsuo Itakura, Kuniko Mizuta, Makoto Sugita, Kazumi Kubozono, Ta To Tran
Publikováno v:
Journal of Cellular Physiology. 229:181-190
TMEM16E/GDD1 has been shown to be responsible for the bone-related late-onset disease gnathodiaphyseal dysplasia (GDD), with the dominant allele (TMEM16E(gdd) ) encoding a missense mutation at Cys356. Additionally, several recessive loss-of-function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab35b61a253e97920f9580a169a66a1d
https://doi.org/10.1002/jcp.24431
https://doi.org/10.1002/jcp.24431
Publikováno v:
Journal of Oral Biosciences. 55:66-72
Gustation is mediated by taste receptor cells that are arranged in taste buds along the oral epithelium, and that express receptors responsible for detecting sweet, bitter, salty, sour, and umami taste stimuli. These five basic taste qualities are li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ead6da7abd8e58009857f5676672a46
https://doi.org/10.1016/j.job.2013.02.002
https://doi.org/10.1016/j.job.2013.02.002
Autor:
Hideyo Yoshida, Eriko Daikoku, Takahiro Kubota, Yoshiki Shiba, Chikara Hirono, Takashi Nakahari, Makoto Sugita, Chikao Shimamoto
Publikováno v:
The Journal of Physiological Sciences. 60:363-371
Ionomycin (IM) at 5 microM mediates the Ca(2+)/H(+) exchange, while IM at 1 microM activates the store-operated Ca(2+) entry channels (SOCs). In this study, the effects of depolarization on both pathways were examined in rat submandibular acinar cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bba08c93fa4e8672afb70c7abab1312
https://doi.org/10.1007/s12576-010-0098-7
https://doi.org/10.1007/s12576-010-0098-7
Publikováno v:
Biomedical Research. 29:131-139
The cytoskeleton serves as a signal modulator for Ca2+ and cAMP-regulated cell functions including the secretion of ions and granule contents. The interaction between Ca2+ and cAMP signaling systems potentiates amylase secretion and suppresses Cl- se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb6f126b20df023f4ee8051b0d83272
https://doi.org/10.2220/biomedres.29.131
https://doi.org/10.2220/biomedres.29.131
Publikováno v:
The journal of physiological sciences : JPS. 66(6)
Intracellular pH (pH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65e29700201e9e2bd0d8d5a9b101df49
https://pubmed.ncbi.nlm.nih.gov/26969473
https://pubmed.ncbi.nlm.nih.gov/26969473
Autor:
Hidemi Kurihara, Hiroyuki Kawaguchi, Tomoyuki Iwata, Katsuhiro Takeda, Tsuyoshi Fujita, Chikara Hirono, Yoshiki Shiba, Yuushi Uchida, Arata Ashikaga, Akiyoshi Kishimoto, Reika Hirata, Hideki Shiba
Publikováno v:
Cytokine. 34(5-6):271-277
Our previous report has shown that Irsogladine maleate (IM) counters and obviates the reduction in gap junction intercellular communication (GJIC) and the increase in IL-8 levels, respectively, induced by outer membrane protein 29 from Actinobacillus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ffa51cb97d6e76c0e6578e633be49d
http://ir.lib.hiroshima-u.ac.jp/00017226
http://ir.lib.hiroshima-u.ac.jp/00017226
Autor:
Chikara Hirono
Publikováno v:
Folia Pharmacologica Japonica. 127:256-260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe9fcd786a879eb070f5d59179a6a67
https://doi.org/10.1254/fpj.127.256
https://doi.org/10.1254/fpj.127.256
Publikováno v:
Biochemical and Biophysical Research Communications. 319:369-374
Elevations of the intracellular levels of cyclic nucleotides appear to cause the cation influx through gustatory cyclic nucleotide-gated (CNGgust) channels expressed in taste cells. Although changes in the oral pH may directly regulate the activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c746cc8a7ebbcd3a4430fe63f337186
https://doi.org/10.1016/j.bbrc.2004.05.009
https://doi.org/10.1016/j.bbrc.2004.05.009