Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chikao Iwai"'
Autor:
Huanlei Huang, Chikao Iwai, Weike Mao, Chang-seng Liang, Jiahao Liu, Virendra K. Sharma, Tingchung Wang, Raju Vulapalli, Shey-Shing Sheu, Michael Fu, Shuji Fukuoka
Publikováno v:
Journal of Molecular and Cellular Cardiology. 44:304-314
Auto-antibodies against the beta(1)-adrenoceptors are present in 30-40% of patients with dilated cardiomyopathy. Recently, a synthetic peptide corresponding to a sequence of the second extracellular loop of the human beta(1)-adrenoceptor (beta(1)-EC(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0e379b15d97585b01ae1647b8178477
https://doi.org/10.1016/j.yjmcc.2007.11.007
https://doi.org/10.1016/j.yjmcc.2007.11.007
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H995-H1003
Cardiac sympathetic transmitter stores are reduced in the failing heart. In this study, we proposed to investigate whether the reduction of cardiac sympathetic neurotransmitters was associated with increased interstitial norepinephrine (NE) and react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619892ea9ebad648acea20b8d9d2e8f5
https://doi.org/10.1152/ajpheart.00569.2005
https://doi.org/10.1152/ajpheart.00569.2005
Autor:
Kenji Kanazawa, Yoshitomo Miyamoto, Masakatsu Shimizu, Eiji Takai, Masayoshi Hashimoto, Hozuka Akita, Chikao Iwai, Mitsuhiro Yokoyama, Yasuaki Matsuda
Publikováno v:
Thrombosis Research. 112:137-142
Masakatsu Shimizu, Kenji Kanazawa, Yasuaki Matsuda, Eiji Takai, Chikao Iwai, Yoshitomo Miyamoto, Masayoshi Hashimoto, Hozuka Akita*, Mitsuhiro Yokoyama Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe Univers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5369e587679068a65b81b82d16e02334
https://doi.org/10.1016/j.thromres.2003.12.002
https://doi.org/10.1016/j.thromres.2003.12.002
Autor:
A Takarada, Chikao Iwai, Eiji Takai, Yoshitomo Miyamoto, Nobuyuki Shiga, Hiroya Kawai, Hozuka Akita, Mitsuhiro Yokoyama, K Mizutani
Publikováno v:
European Heart Journal. 22:2284-2289
Aims Dilated cardiomyopathy is partly caused by a mutation of some cytoskeletal or nuclear envelope proteins. It has been confirmed recently that a missense mutation of the gene encoding desmin, a cytoskeletal protein, can cause dilated cardiomyopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a4c4e05570474e975fcc958354c46b
https://doi.org/10.1053/euhj.2001.2836
https://doi.org/10.1053/euhj.2001.2836
Autor:
Kunihiro Nishimura, Eiji Hiraoka, Daisuke Sugiyama, Yukio Yamori, Kenji Kanazawa, Masayoshi Hashimoto, Yasuaki Matsuda, Yoshitomo Miyamoto, Chikao Iwai, Kazuo Ito, Hozuka Akita
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 73(4)
Background: Estrogen is considered to be cardioprotective, but estrogen replacement therapy for postmenopausal women has not shown results for either primary or secondary cardiovascular event prevention. During normal pregnancy, women have significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c391bbe522d4275bfd8640b1db10479
https://pubmed.ncbi.nlm.nih.gov/19225209
https://pubmed.ncbi.nlm.nih.gov/19225209
Dilated human cardiomyopathy is associated with suppression of the prosurvival phosphatidylinositol-3-kinase (PI3K)/Akt and STAT3 pathways. The present study was carried out to determine if restoration of the PI3K/Akt and STAT3 activity by darbepoeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5d5dfd6d7109c8b1c850b09b98e00b
https://europepmc.org/articles/PMC2599925/
https://europepmc.org/articles/PMC2599925/
Autor:
Chang-seng Liang, Weike Mao, Michael Fu, Shuji Fukuoka, Shey-Shing Sheu, Chikao Iwai, Virendra K. Sharma, Jiahao Liu
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 293(3)
Evidence suggests that the autoimmune cardiomyopathy produced by a peptide corresponding to the sequence of the second extracellular loop of the β1-adrenergic receptor (β1-ECII) is mediated via a biologically active anti-β1-ECII antibody, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38fca53d748aa19212db5943624e399
https://pubmed.ncbi.nlm.nih.gov/17545481
https://pubmed.ncbi.nlm.nih.gov/17545481
Autor:
Ken-ichi Hirata, Eiji Hiraoka, Chikao Iwai, Yoshitomo Miyamoto, Masakatsu Shimizu, Masayoshi Hashimoto, Yasuaki Matsuda, Hozuka Akita, Mitsuhiro Yokoyama, Tatsuro Ishida, Teishi Kajiya, Kenji Kanazawa
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 71(6)
Background Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism and promotes monocytes recruitment. The local expression of EL could influence atherogenesis directly, in addition to its systemic ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ed0570a0fe25662d155ca3062fb7e0
https://pubmed.ncbi.nlm.nih.gov/17526978
https://pubmed.ncbi.nlm.nih.gov/17526978
Publikováno v:
American journal of physiology. Cell physiology. 290(5)
Norepinephrine (NE) induces endoplasmic reticulum (ER) unfolded protein response and reduces maturation and translocation of NE transporter to cell membrane via enhanced formation of reactive oxygen species in PC-12 cells. In the present study, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9214f6f2a87aa431d9b4feb3e6568e3c
https://pubmed.ncbi.nlm.nih.gov/16338971
https://pubmed.ncbi.nlm.nih.gov/16338971
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 288(5)
Cardiac norepinephrine (NE) uptake is reduced in cardiomyopathy. This change is associated with a decrease of NE transporter (NET) receptor and can be reproduced in PC12 cells by extracellular NE. To study whether this effect of NE is mediated via im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebac7b0291fd101ed0e30af20bdb6668
https://pubmed.ncbi.nlm.nih.gov/15626688
https://pubmed.ncbi.nlm.nih.gov/15626688