Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chikako Hara-Miyauchi"'
Autor:
Gakuya Takamatsu, Yoko Manome, Jun-Seok Lee, Kanako Toyama, Tomoko Hayakawa, Chikako Hara-Miyauchi, Minami Hasegawa-Ogawa, Chiaki Katagiri, Tsuyoshi Kondo, Hirotaka James Okano, Masayuki Matsushita
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102915- (2022)
Induced pluripotent stem cells (iPSCs) obtained from genetically characterized patients benefit the biological study of bipolar disorder (BD). Here, we present iPSC lines from three-generation patients with BD and recurrent depressive disorder (RDD)
Externí odkaz:
https://doaj.org/article/e4fab64271504b4fb554a55903cc4ec4
Autor:
Keiko Bono, Chikako Hara-Miyauchi, Shunsuke Sumi, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Mutations in the Vacuolar protein sorting 35 (VPS35) gene have been linked to familial Parkinson’s disease (PD), PARK17. VPS35 is a key component of the retromer complex, which plays a central role in endosomal trafficking. However, whethe
Externí odkaz:
https://doaj.org/article/39fd3bdaa6d34c84a85400c9f244dcba
Autor:
Hirotaka James Okano, Keiko Bono, Chikako Hara-Miyauchi, Yasuyuki Iguchi, Shunsuke Sumi, Hisayoshi Oka
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Mutations in the Vacuolar protein sorting 35 (VPS35) gene have been linked to familial Parkinson’s disease (PD), PARK17. VPS35 is a key component of the retromer complex, which plays a central role in endosomal trafficking. However, whether and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb73dfa8209674609a177b1186d9160
http://europepmc.org/articles/PMC7542911
http://europepmc.org/articles/PMC7542911
Autor:
Chikako Hara-Miyauchi, Kenji Sakimura, Minami Hasegawa, Hirotaka James Okano, Hiroki Ohta, Hideyuki Okano
Publikováno v:
Neuroscience Research. 106:12-22
Diagnostic biomarkers for amyotrophic lateral sclerosis (ALS) have yet to be identified. One of the causes of neuronal cell death in neurodegenerative diseases is abnormal RNA metabolism, although the mechanisms by which this occurs are unclear. Dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c58e98f72e5ac046fee0a499479d8c
https://doi.org/10.1016/j.neures.2015.11.009
https://doi.org/10.1016/j.neures.2015.11.009
Autor:
Kazuhisa Sekimizu, Chikako Hara-Miyauchi, Nagisa Arimitsu, Kazuki Nakao, Minami Hasegawa-Ogawa, Hirotaka James Okano, Tomohiro Maruyama, Yuki Maemoto, Hiroshi Hamamoto, Takayo Ohto-Nakanishi, Kei Matsumoto, Yuki Enda, Shigeru Yanagi, Katsuko Tani, Hiroki Nakanishi, Takeshi Tokuyama, Takashi Baba, Mitsuo Tagaya
Publikováno v:
Cell Death and Disease, Vol 9, Iss 8, Pp 1-15 (2018)
Cell Death & Disease
Cell Death & Disease
DDHD2/KIAA0725p is a mammalian intracellular phospholipase A1 that exhibits phospholipase and lipase activities. Mutation of the DDHD2 gene causes hereditary spastic paraplegia (SPG54), an inherited neurological disorder characterized by lower limb s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b1571f2ad77e59151d56140ff1aac7
https://doi.org/10.1038/s41419-018-0815-3
https://doi.org/10.1038/s41419-018-0815-3
Autor:
Seiji Okada, Yumi Matsuzaki, Akimasa Yasuda, Takeshi Imamura, Takashi Fukano, Masaya Nakamura, Atsushi Miyawaki, Hirotaka James Okano, Aki Hanyu, Osahiko Tsuji, Hideyuki Okano, Chikako Hara-Miyauchi, Chihiro Akazawa
Publikováno v:
Biochemical and Biophysical Research Communications. 419:188-193
The current utility of bioluminescence imaging is constrained by a low photon yield that limits temporal sensitivity. Here, we describe an imaging method that uses a chemiluminescent/fluorescent protein, ffLuc-cp156, which consists of a yellow varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7811d6c93c67680a4dbc50248d15b4
https://doi.org/10.1016/j.bbrc.2012.01.141
https://doi.org/10.1016/j.bbrc.2012.01.141
Autor:
Reona Kobayashi, Junko Takahashi-Fujigasaki, Takashi Inoue, Chikako Hara-Miyauchi, Hirotaka James Okano, Erika Sasaki, Seiji Shiozawa, Hideyuki Okano
Publikováno v:
Neuroscience research. 106
The synaptic protein α-synuclein has been identified as a major component of Lewy bodies, a pathological hallmark of Parkinson's disease (PD). Prior to the formation of Lewy bodies, mislocalization and aggregation of the α-synuclein in brain tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a2a22c0d952cb508a810467bad859c
https://pubmed.ncbi.nlm.nih.gov/26643383
https://pubmed.ncbi.nlm.nih.gov/26643383
Autor:
Satsuki Mochizuki, Chikako Hara-Miyauchi, Hitoshi Abe, H Fukuda, N Yamaguchi, Yasunori Okada, M Nakayama, Hirotaka James Okano, Hideyuki Okano, Jeanine D'Armiento
Publikováno v:
British Journal of Cancer
Background: Although matrix metalloproteinases (MMPs) are implicated in tumourigenesis and cancer progression, the role of MMP-13 in melanoma cell metastases is poorly understood. Methods: Lung metastases of mouse melanoma B16BL6 cells were analysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466f548b42463bc17a995b9a2125dfa1
https://pubmed.ncbi.nlm.nih.gov/22015555
https://pubmed.ncbi.nlm.nih.gov/22015555
Autor:
Takayoshi Inoue, Ryota Suzuki, Chihiro Akazawa, Atsuyuki Yamataka, Chikako Hara-Miyauchi, Katsumi Miyahara, Nobuharu Suzuki
Publikováno v:
Neuroscience Research. 71:e128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5ade39c130ce833156a5fa7f1aa6f2
https://doi.org/10.1016/j.neures.2011.07.546
https://doi.org/10.1016/j.neures.2011.07.546