Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chikako Fukukawa"'
Autor:
Arata Shimo, Meng-Lay Lin, Toshihiko Nishidate, Kie Naito, Yusuke Nakamura, Toyomasa Katagiri, Kyoko Kijima, Chikako Fukukawa, Masahiko Ajiro, Jae-Hyun Park
Publikováno v:
Cancer Science. 100:1443-1450
Through analysis of the detailed genome-wide gene expression profiles of 81 breast tumors, we identified a novel gene, G-patch domain containing 2 (GPATCH2), that was overexpressed in the great majority of breast cancer cases. Treatment of breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a83a5b6933ef7381606d9402c11e6a
https://doi.org/10.1111/j.1349-7006.2009.01185.x
https://doi.org/10.1111/j.1349-7006.2009.01185.x
Autor:
Bishnuhari Paudyal, Chikako Fukukawa, Tetsuya Higuchi, Shinji Yamamoto, Noboru Oriuchi, Pramila Paudyal, Yasuhiko Iida, Yusuke Nakamura, Toyomasa Katagiri, Keigo Endo, Hiroki Yoshioka, Hirofumi Hanaoka
Publikováno v:
Annals of Nuclear Medicine. 23:479-485
Frizzled homolog 10 (FZD10) is expressed at high levels on the cell surface of almost all synovial sarcoma tissues, but is absent in most normal organs. In a previous study, yttrium-90 ((90)Y)-labeled anti-FZD10 antibody (MAb 92-13) showed considerab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a27d2f11bf15e2d5c14cf60b455415
https://doi.org/10.1007/s12149-009-0265-1
https://doi.org/10.1007/s12149-009-0265-1
Autor:
Chikako Fukukawa, Tatsuhiko Tsunoda, Toyomasa Katagiri, Yusuke Nakamura, Satoshi Nagayama, Junya Toguchida
Publikováno v:
Oncogene. 28:1110-1120
We previously reported that Frizzled homologue 10 (FZD10), a member of the Wnt signal receptor family, was highly and specifically upregulated in synovial sarcoma and played critical roles in its cell survival and growth. We here report a possible mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3b2ebdfdf87b204b3ab8cd6bd59cb1
https://doi.org/10.1038/onc.2008.467
https://doi.org/10.1038/onc.2008.467
Publikováno v:
Cancer Letters. 226:155-160
In this study, we focus on the potential interaction of pp32/I-1(PP2A) (pp32) with the Raf-MEK-ERK signaling pathway. We show that overexpressed pp32 suppresses Raf-1 activation, thereby downregulating the level of ERK activation. This suppression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123489374bed653675d21150fc21d4fe
https://doi.org/10.1016/j.canlet.2004.11.026
https://doi.org/10.1016/j.canlet.2004.11.026
Publikováno v:
Journal of Biochemistry. 126:34-40
Porcine cardiac myosin monomers in equilibrium with filaments under physiological conditions were observed to have two conformations, extended and folded forms, upon electron microscopy and gel filtration HPLC. The conformational state was independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01dae8221acc186b43ba16f98fe6642
https://doi.org/10.1093/oxfordjournals.jbchem.a022433
https://doi.org/10.1093/oxfordjournals.jbchem.a022433
Autor:
Toyomasa Katagiri, Toshihiko Nishidate, Koji Ueda, Chikako Fukukawa, Yusuke Nakamura, Jung Won Kim
Publikováno v:
International journal of oncology. 37(4)
Through genome-wide gene expression profile analysis of breast cancer, we identified a gene, chromosome 12 open reading frame 32 (C12orf32), to be involved in mammary carcinogenesis. Semiquantitative RT-PCR and Northern blot analysis confirmed C12orf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb6a278557008a90b549b2007427e2c
https://pubmed.ncbi.nlm.nih.gov/20811708
https://pubmed.ncbi.nlm.nih.gov/20811708
Publikováno v:
Genes, chromosomescancer. 49(10)
To investigate the molecular mechanism of mammary carcinogenesis and identify novel molecular targets for breast cancer therapy, we analyzed genome-wide gene expression profiles of 81 clinical breast cancer samples. Here, we report the critical role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc51d38a2c32bf3f09b282df11aedbf
https://pubmed.ncbi.nlm.nih.gov/20589935
https://pubmed.ncbi.nlm.nih.gov/20589935
Autor:
Toyomasa Katagiri, Yataro Daigo, Masahiko Ajiro, Meng-Lay Lin, Toshihiko Nishidate, Jae-Hyun Park, Koji Ueda, Yusuke Nakamura, Chikako Fukukawa, Hidewaki Nakagawa
Publikováno v:
International journal of oncology. 35(4)
We here report identification and characterization of required for cell differentiation 1 homolog (RQCD1) as a potential therapeutic target for breast cancer. Gene-expression profiling analysis of breast cancer cells, semi-quantitative RT-PCR, Northe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7885039f63e33953b3864c342059cafe
https://pubmed.ncbi.nlm.nih.gov/19724902
https://pubmed.ncbi.nlm.nih.gov/19724902
Autor:
Satoshi Nagayama, Yoshiki Kohno, Yoshiharu Sakai, Go Watanabe, Chikako Fukukawa, Tomoki Aoyama, Hajime Kubo, Yusuke Nakamura, Toyomasa Katagiri, Junya Toguchida, Eiji Yamada
Publikováno v:
Cancer science. 100(3)
We investigated the immunohistochemical expression patterns of Frizzled homolog 10 (FZD10), a cell-surface receptor for molecules in the Wnt pathway, in tissue samples derived from 104 patients with colorectal cancers (CRCs). There was no immunoreact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4f6d0bbe8a01d3eea40004070c6291
https://pubmed.ncbi.nlm.nih.gov/19134005
https://pubmed.ncbi.nlm.nih.gov/19134005
Publikováno v:
Future oncology (London, England). 1(6)
Although the specific chromosomal translocation and fusion gene SYT-SSX in synovial sarcoma (SS) has been identified, the molecular mechanism of its tumorigenesis is largely unknown. Recent gene-expression profiles of soft-tissue tumors using cDNA mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a642f4bd1fc4858621e17c35a8fbbdbb
https://pubmed.ncbi.nlm.nih.gov/16556060
https://pubmed.ncbi.nlm.nih.gov/16556060