Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chika Taniyama"'
Autor:
Sayuri Ito, Ai Ishii, Naoko Kakusho, Chika Taniyama, Satoshi Yamazaki, Rino Fukatsu, Asako Sakaue-Sawano, Atsushi Miyawaki, Hisao Masai
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36372 (2012)
BACKGROUND: Depletion of replication factors often causes cell death in cancer cells. Depletion of Cdc7, a kinase essential for initiation of DNA replication, induces cancer cell death regardless of its p53 status, but the precise pathways of cell de
Externí odkaz:
https://doaj.org/article/a56f2f0886fe4e928491b46f09122641
Autor:
Takayuki Irie, Tokiko Asami, Ayako Sawa, Yuko Uno, Chika Taniyama, Yoko Funakoshi, Hisao Masai, Masaaki Sawa
Publikováno v:
Journal of Medicinal Chemistry; 10/14/2021, Vol. 64 Issue 19, p14153-14164, 12p
Autor:
Takayuki Irie, Chika Taniyama, Yuko Uno, Hisao Masai, Mitsuharu Hanada, Masaaki Sawa, Yoko Funakoshi, Tokiko Asami, Ayako Sawa
Publikováno v:
European journal of medicinal chemistry. 130
Cdc7 is a serine-threonine kinase and plays a conserved and important role in DNA replication, and it has been recognized as a potential anticancer target. Herein, we report the design, synthesis and structure-activity relationship of novel furanone
Autor:
Naoko Kakusho, Gaik-theng Toh, Rino Fukatsu, Ho-Jin Chang, Satoshi Yamazaki, Hisao Masai, Kazuo Yanagi, Ryo Kitamura, Chika Taniyama, Naoko Arai, Yong-Soon Cho
Publikováno v:
Journal of Biological Chemistry. 286:23031-23043
Cdc7 is a serine/threonine kinase conserved from yeasts to human and is known to play a key role in the regulation of initiation at each replication origin. Its catalytic function is activated via association with the activation subunit Dbf4/activato
Publikováno v:
Genes to Cells. 8:251-261
Backgrounds: PriA protein, a DEXH-type helicase with C2C2 zinc-finger motifs, plays essential roles in RecA-dependent modes of Escherichia coli chromosomal DNA replication, namely inducible and constitutive stable DNA replication (iSDR and cSDR respe
Publikováno v:
Journal of Biological Chemistry. 277:38062-38071
PriA protein is essential for RecA-dependent DNA replication induced by stalled replication forks in Escherichia coli. PriA is a DEXH-type DNA helicase, ATPase activity of which depends on its binding to structured DNA including a D-loop-like structu
Autor:
Atsushi Miyawaki, Ai Ishii, Sayuri Ito, Naoko Kakusho, Satoshi Yamazaki, Chika Taniyama, Rino Fukatsu, Asako Sakaue-Sawano, Hisao Masai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36372 (2012)
PLoS ONE, Vol 7, Iss 5, p e36372 (2012)
Background Depletion of replication factors often causes cell death in cancer cells. Depletion of Cdc7, a kinase essential for initiation of DNA replication, induces cancer cell death regardless of its p53 status, but the precise pathways of cell dea
Publikováno v:
The Journal of biological chemistry. 283(28)
Cdc7 is a serine-threonine kinase that regulates initiation and progression of DNA replication. The activity of purified Cdc7 kinase is significantly stimulated by polyamines such as spermine or spermidine. Positively charged polymers of lysine or ar
Autor:
Takayuki Irie, Chika Taniyama, Masaaki Sawa, Ayako Sawa, Yoko Funakoshi, Hisao Masai, Yuko Uno, Tokiko Asami
Publikováno v:
Molecular Cancer Therapeutics. 14:A180-A180
Introduction> Cell cycle kinases have been recognized as potential anticancer targets, because loss of regulated cell cycle progression would lead to uncontrolled cell growth and development of cancer. Cdc7 kinase is involved in regulation of the cel
Autor:
Hisao Masai, Keiko Ogino, Chika Taniyama, Ai Ishii, Taku Tanaka, Etsuko Matsui, Kiyoshi Ohtani, Ken-ichi Arai, Katsuyuki Tamai, Seiji Matsumoto, Toshiko Kobayashi, Naoko Kakusho, Jung Min Kim
Publikováno v:
The Journal of biological chemistry. 281(51)
Cdc7 kinase, conserved from yeasts to human, plays important roles in DNA replication. However, the mechanisms by which it stimulates initiation of DNA replication remain largely unclear. We have analyzed phosphorylation of MCM subunits during cell c