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of 3
pro vyhledávání: '"Chika Tamamura"'
Autor:
Seiji Katayama, Shinji Hourai, Hiroyasu Tanaka, Toru Kodo, Ryu Nagata, Shuji Masumoto, Nobuyuki Ae, Chika Tamamura
Publikováno v:
Journal of Medicinal Chemistry. 46:691-701
A series of tricyclic indole-2-carboxylic acid derivatives were synthesized and evaluated by the radioligand binding assay and the anticonvulsant effects in the mouse NMDA-induced seizure model. Among them, derivatives of 3S-(-)-4 such as 3a, 3f, and
Autor:
Hirokazu Yasuda, Hideki Sakamoto, Yukihiro Ohno, Chika Tamamura, Akiko Kawabe, Hiroyasu Tanaka, Mitsutaka Nakamura, Ken-ichi Ohtani, Yoshimi Maruoka
Publikováno v:
General Pharmacology: The Vascular System. 29:645-649
1. The effects of N-methyl-D-aspartate (NMDA) receptor glycine-binding site antagonists 7-chlorokynurenate (7-Clkyn) and (±)-3-amino-1-hydroxy-2-pyrrolidone (HA-966) on spinal reflexes in an isolated spinal cord that was maintained in Mg2+-free medi
Autor:
Ken-ichi Otani, Chika Tamamura, Yoshimi Maruoka, Hirokazu Yasuda, Hiroyasu Tanaka, Yukihiro Ohno, Mitsutaka Nakamura
Publikováno v:
Japanese journal of pharmacology. 76(3)
We examined the effects of novel tricyclic quinoxalinedione derivatives, SM-18400 ((S)-9-chloro-5-[p-aminomethyl-o-(carboxymethoxy)phenylcarbamoylmethyl]-6, 7-dihydro-1H, 5H-pyrido[1, 2, 3-de]quinoxaline-2, 3-dione hydrochloride trihydrate) and its a