Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Chika Nakada"'
Publikováno v:
ChemBioChem. 18:2145-2155
The functions of Val483, Trp534, and Met729 in Euphorbia tirucalli β-amyrin synthase were revealed by comparing the enzyme activities of site-directed mutants against that of the wild type. The Gly and Ala variants with a smaller bulk size at positi
Publikováno v:
Organic & Biomolecular Chemistry. 15:177-188
Many of the functions of the active site residues in β-amyrin synthase and its catalytic mechanism remain unclear. Herein, we examined the functions of the highly conserved Phe413, Tyr259, and Trp257 residues in the β-amyrin synthase of Euphorbia t
Publikováno v:
Org. Biomol. Chem.. 12:3836-3846
β-Amyrin, a triterpene, is widely distributed in plants and its glycosides confer important biological activities. Mutagenesis studies on β-amyrin synthase are very limited as compared with those of squalene-hopene cyclase and lanosterol synthase.