Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chika Adachi"'
Autor:
Chika Adachi, Kazunari Sekiyama, Osamu Hashimoto, Yuuki Ushiro, Yoshihisa Hasegawa, Takefumi Kikusui, Kentaro Tanemura
Publikováno v:
Biochemical and Biophysical Research Communications. 385:319-323
To study the function of activin E, a TGF-beta superfamily member, in the regulation of affective behavior, we investigated the behavior of transgenic mice overexpressing activin E (TgActbetaE mice). Male TgActbetaE mice showed aggressive behavior in
Autor:
Hiromi Hagiwara, Shigehisa Hirose, Chika Adachi, Mitsuhide Naruse, Eri Otsuka, Atsuto Inoue, Kiyoko Naruse, Yoshiharu Hiruma, Hiroshi Demura
Publikováno v:
Journal of Biochemistry. 126:168-173
Ipriflavone (7-isopropoxy-3-phenyl-4H-1-benzopyran-4-one) is a synthetic flavonoid that has been shown to stimulate the activity of osteoblasts. We show here that ipriflavone also promotes the deposition of calcium and the formation of mineralized no
Autor:
Takanobu Yoshimoto, Toshirou Seki, Akiyo Tanabe, Mitsuhide Naruse, Hiroshi Demura, Toshihiro Imaki, Kiyoko Naruse, Reiko Demura, Chika Adachi
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:S395-S398
We studied target organ-protective effects of aracepril, an angiotensin-converting enzyme inhibitor, and the expression of endothelin-1 (ET-1) and nitric oxide synthase (NOS) mRNA. Aracepril (30 mg/kg) was administered orally to Izumo strain of strok
Autor:
Tomohito Kawami, Atsuhiko Ishida, Noriko Fujitani, Chika Adachi, Yasuhiro Ishihara, Takeshi Yamazaki
Publikováno v:
Life sciences. 99(1-2)
Aims Neuroactive steroids are reported to protect neurons from various harmful compounds; however, the protective mechanisms remain largely unclear. In this study, we examined the suppressive effects of 17β-estradiol (E2) on tributyltin (TBT)-induce
Autor:
Toshirou Seki, Kiyoko Naruse, Takanobu Yoshimoto, Mitsuhide Naruse, Sachiko Takagi, Akiyo Tanabe, Kazue Takano, Chika Adachi
Publikováno v:
Journal of Cardiovascular Pharmacology. 36:S176-S178
Although evidence has been accumulated to support a role of endothelin-1 (ET-1) in cardiac hypertrophy, details of the pathophysiological significance of ET-1 in cardiac hypertrophy remain to be elucidated. In the present study, we investigated the e
Autor:
Takanobu Yoshimoto, Toshirou Seki, Sachiko Takagi, Mitsuhide Naruse, Chika Adachi, Kazue Takano, Akiyo Tanabe, Toshifumi Watanabe, Kiyoko Naruse, Toshihiro Imaki
Publikováno v:
Journal of Cardiovascular Pharmacology. 36:S334-S336
We have demonstrated previously that endothelin-1 (ET-1) mRNA expression is increased in hypertensive rats. The aim of the study reported here was to elucidate the effects of the endothelin (ET) receptor antagonist on the hemodynamic and biochemical
Autor:
Toshirou Seki, Mitsuhide Naruse, Akiyo Tanabe, Chika Adachi, Takanobu Yoshimoto, Kazue Takano, Sachiko Takagi, Kiyoko Naruse
Publikováno v:
Scopus-Elsevier
Recent studies revealed important roles for endothelin-1 (ET-1) in the pathogenesis of hypertension. Whether ET-1 could be a primary cause of hypertension or a secondary factor associated with hypertension, however, remains unknown. In this study, we
Autor:
Jun Kagawa, Akiyo Tanabe, Takanobu Yoshimoto, Chika Adachi, Kiyoko Naruse, Mitsuhide Naruse, Yoko Ishihara, Sachiko Takagi, Kazue Takano
Publikováno v:
Journal of Cardiovascular Pharmacology. 36:S198-S200
Although smoking has been suggested to be involved in the development of cardiovascular diseases, details of the mechanism still need to be revealed. We investigated the effects of cigarette smoking on the tissue mRNA expression of endothelin-1 (ET-1
Autor:
Naoko Mishina, Mitsuhide Naruse, Kiyoko Naruse, Reiko Demura, Takanobu Yoshimoto, Hiroshi Demura, Akiyo Tanabe, Toshihiro Imaki, Toshirou Seki, Chika Adachi
Publikováno v:
Journal of hypertension. 17(1)
OBJECTIVE The aim of this study was to investigate the effects of calcium channel blockers on messenger RNA expression of endothelin-1 and endothelial-type nitric oxide synthase in the cardiovascular tissue of stroke-prone spontaneously hypertensive
Autor:
Fumiyo Tamura, Kohei Akimoto, Yoshihiro Tabuchi, Takeshi Kikutani, Yasuo Nakamura, Toyohiko Hayashi, Kenshun Ishii, Chika Adachi
Publikováno v:
Journal of Life Support Engineering. 18:49-49