Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Chijian Zuo"'
Autor:
Jingsheng Cai, Zonghao Qiu, William Chi‐Shing Cho, Zheng Liu, Shaoyi Chen, Haoran Li, Kezhong Chen, Yun Li, Chijian Zuo, Mantang Qiu
Publikováno v:
MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)
Abstract Small molecule drugs are increasingly emerging as innovative and effective treatments for various diseases, with mRNA therapeutics being a notable representative. The success of COVID‐19 vaccines has underscored the transformative potentia
Externí odkaz:
https://doaj.org/article/22a9147ab92f479e8445ce3bd7c1dded
Autor:
Jiali Yang, Jiafeng Zhu, Jiaojiao Sun, Yiyun Chen, Yaran Du, Yiling Tan, Linpeng Wu, Mengting Zhai, Lixiang Wei, Na Li, Ke Huang, Qiangbo Hou, Zhenbo Tong, Andreas Bechthold, Hao Tian, Zhenhua Sun, Chijian Zuo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 184-197 (2022)
The success of the two mRNA vaccines developed by Moderna and BioNTech during the COVID-19 pandemic increased research interest into the application of mRNA technologies. Compared with the canonical linear mRNA used in these vaccines, circular mRNA h
Externí odkaz:
https://doaj.org/article/8c8b3f2e71ad408e88adf7ed1fab8d11
Autor:
Philipp Schwarzer, Olga Tsypik, Chijian Zuo, Ahmad Alali, Julia Wunsch-Palasis, Tanja Heitzler, Jana Derochefort, Mirjam Bernhardt, Xiaohui Yan, Thomas Paululat, Andreas Bechthold
Publikováno v:
Molecules, Vol 25, Iss 8, p 1955 (2020)
The biological active compound rishirilide B is produced by Streptomyces bottropensis. The cosmid cos4 contains the complete rishirilide B biosynthesis gene cluster. Its heterologous expression in the host Streptomyces albus J1074 led to the producti
Externí odkaz:
https://doaj.org/article/c05ab7b0c9e943e59b63209d672bf58c
Autor:
Zonghao Qiu, Qiangbo Hou, Yang Zhao, Jiafeng Zhu, Mengting Zhai, Daolei Li, Yi Li, Chunxi Liu, Na Li, Yifei Cao, Jiali Yang, Zhenhua Sun, Chijian Zuo
Translatable circular RNAs (circRNAs) are emerging as a crucial molecular format for transient protein expression, with high potential to be an alternative for linear mRNA to reshape the landscape of mRNA pharmaceutical industry. Canonical Anabaena p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb128390517f57258f2c5019356b2c1e
https://doi.org/10.1101/2022.06.20.496777
https://doi.org/10.1101/2022.06.20.496777
Autor:
Ke Huang, Na Li, Yingwen Li, Jiafeng Zhu, Qianyi Fan, Jiali Yang, Yinjia Gao, Yupin Liu, Qiangbo Hou, Shufeng Gao, Ke Wei, Chao Deng, Chijian Zuo, Zhenhua Sun
mRNA vaccines have emerged as a most promising and potent platform in the fight against various diseases including the COVID-19 pandemic. However, the intrinsic instability, varying side effects associated with the delivery systems, and continuous em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6863ea5db0683946fea2335c183b31b
https://doi.org/10.1101/2022.05.12.491597
https://doi.org/10.1101/2022.05.12.491597
Autor:
Jiali Yang, Jiaojiao Sun, Jiafeng Zhu, Yaran Du, Yiling Tan, Lixiang Wei, Yang Zhao, Qiangbo Hou, Yan Zhang, Zhenhua Sun, Chijian Zuo
Although proteolysis targeting chimera (PROTAC) technology that hijacking the ubiquitin-proteasome system (UPS) to artificially degrade protein is an emerging promising technology for many undruggable targets, it still faces several challenges, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156a0ec418b8f7f9d09cfae7012eff1c
https://doi.org/10.1101/2022.04.22.489232
https://doi.org/10.1101/2022.04.22.489232
Autor:
Lixiang Wei, Andreas Bechthold, Ke Huang, Jiali Yang, Jiafeng Zhu, Zhenbo Tong, Mengting Zhai, Qiangbo Hou, Jiaojiao Sun, Sun Zhenhua, Chijian Zuo, Na Li, Linpeng Wu, Yiling Tan, Yaran Du, Yiyun Chen
The application of mRNA as a novel kind of vaccine has been proved recently, due to the emergence use authorization (EUA) by FDA for the two COVID-19 mRNA vaccines developed by Moderna and BioNTech. Both of the two vaccines are based on canonical lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be2fd598bfa59900fab3991f790df11
https://doi.org/10.1101/2021.11.01.466725
https://doi.org/10.1101/2021.11.01.466725
Autor:
Olga Tsypik, Jana Derochefort, Mirjam Bernhardt, Chijian Zuo, Xiaohui Yan, Philipp Schwarzer, Thomas Paululat, Tanja Heitzler, Andreas Bechthold, Julia Wunsch-Palasis, Ahmad Alali
Publikováno v:
Molecules
Volume 25
Issue 8
Molecules, Vol 25, Iss 1955, p 1955 (2020)
Volume 25
Issue 8
Molecules, Vol 25, Iss 1955, p 1955 (2020)
The biological active compound rishirilide B is produced by Streptomyces bottropensis. The cosmid cos4 contains the complete rishirilide B biosynthesis gene cluster. Its heterologous expression in the host Streptomyces albus J1074 led to the producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e954c30f86c1e92973ccd90fa24dc8d
Autor:
Xiaoying Zhao, Ning Zhang, Jiake Xu, Guoli Hu, Yu Shi, Wen Wu, Chuandong Wang, Xiaoling Zhang, Chijian Zuo
Publikováno v:
Oncotarget
Although the mechanisms of Tumor necrosis factor alpha (TNF-α) on facilitating osteoclast differentiation and bone resorption is well known, the mechanisms behind the suppression of the osteoblast differentiation from mesenchymal stem cells (MSCs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ca4a7387278f04c4c06a9c99f000cd
https://doi.org/10.18632/oncotarget.23373
https://doi.org/10.18632/oncotarget.23373