Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chijen R. Lin"'
Publikováno v:
Current Opinion in Genetics & Development. 15:332-340
The pituitary gland functions as a relay between the hypothalamus and peripheral target organs that regulate basic physiological functions, including growth, the stress response, reproduction, metabolism and lactation. The development of the pituitar
Autor:
Daniel P. Szeto, Michael G. Rosenfeld, Forrest Liu, Chijen R. Lin, Shawn M. O'Connell, Chrissa Kioussi, Juan Carlos Izpisúa-Belmonte, Paola Briata
Publikováno v:
Nature. 401:279-282
Pitx1 and Pitx2 are highly homologous, bicoid-related transcription factors. Pitx2 was initially identified as the gene responsible for the human Rieger syndrome, an autosomal dominant condition that causes developmental abnormalities. Pitx2 is asymm
Autor:
Donna M. Simmons, Michael G. Rosenfeld, Larry W. Swanson, R. E. Park, Chijen R. Lin, Xi He, R. Gerrero
Publikováno v:
Molecular and Cellular Biology. 11:1739-1744
Tst-1, a member of the POU domain gene family, is expressed in specific neurons and in myelinating glia in the mammalian nervous system. Bacterially expressed Tst-1 binds specifically to the promoter of the gene encoding myelin protein P0, a Schwann
Autor:
Xi He, Renee Gerrero, Donna M. Simmons, Ronald E. Park, Chijen R. Lin, Larry W. Swanson, Michael G. Rosenfeld
Publikováno v:
Molecular and Cellular Biology. 11:1739-1744
Publikováno v:
Reviews in endocrinemetabolic disorders. 5(1)
Autor:
Michael G. Rosenfeld, Toshimitsu Kishimoto, Ola Hermanson, Jelena Radulovic, Marko Radulovic, Farideh Hooshmand, Joachim Spiess, Christina Schrick, Chijen R. Lin
Publikováno v:
Karolinska Institutet
Corticotropin-releasing hormone (Crh), a 41-residue polypeptide, activates two G-protein-coupled receptors, Crhr1 and Crhr2, causing (among other transductional events) phosphorylation of the transcription factor Creb. The physiologic role of these r
Different truncated and conformationally constrained analogs of corticotropin-releasing factor (CRF) were synthesized on the basis of the amino acid sequences of human/rat CRF (h/rCRF), ovine CRF (oCRF), rat urocortin (rUcn), or sauvagine (Svg) and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0014f1a432d81a77d9c9640baca8ca7
https://europepmc.org/articles/PMC28031/
https://europepmc.org/articles/PMC28031/
Autor:
Sheng-Cai Lin, Bogi Andersen, Linda Erkman, Peng Li, Michael G. Rosenfeld, Marcus D. Schonemann, Robert J. McEvilly, Eric E. Turner, Chijen R. Lin
Publikováno v:
Neural Cell Specification ISBN: 9781461357902
The precise molecular mechanisms by which distinct, mature neuronal phenotypes arise from a common primordium, in response to specific morphogens and signals, remains a fundamental question in neurobiology. We have discovered and characterized eight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65cdabd21110ebf72f4e51efeb6e6787
https://doi.org/10.1007/978-1-4615-1929-4_6
https://doi.org/10.1007/978-1-4615-1929-4_6
Autor:
Paul E. Sawchenko, Michael G. Rosenfeld, Sheng-Cai Lin, Aldons J. Lusis, Ilya Gukovsky, Chijen R. Lin
Publikováno v:
Nature. 364(6434)
The molecular basis for the little (lit) mouse phenotype, characterized by a hypoplastic anterior pituitary gland, is the mutation of a single nucleotide that alters Asp 60 to Gly in the growth hormone releasing factor receptor. Detailed analysis of
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(9)
Calcium influx in response to extracellular signals can modulate gene transcription. A constitutive, calcium/calmodulin-independent mutant of type II calcium/calmodulin-dependent protein kinase was capable of increasing the transcription rate of spec