Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chii-Ming Lai"'
Autor:
Ronald M. Klabe, James D. Rodgers, Jo Anne Saye, Susan Jeffrey, Sharon Diamond, Jeffrey W. Corbett, Paul Anderson, Chii-Ming Lai, Soo S. Ko, Susan Erickson-Viitanen, Lee T. Bacheler, George L. Trainor, Shelley R. Rabel, Stephen P. Adams
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:2893-2897
A research program targeted toward the identification of expanded-spectrum nonnucleoside reverse transcriptase inhibitors which possess increased potency toward K103N-containing mutant human immunodeficiency virus (HIV) and which maintain pharmacokin
Autor:
Dennis M. Garner, Vanessa C. Peterman, Henry J. Pieniaszek, John E. Gray, Bernice L. Brogdon, Chii-Ming Lai
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 17:427-434
A simple, specific, and sensitive high-performance liquid chromatographic (HPLC) assay utilizing ultraviolet (UV) detection for the determination of bisnafide in human plasma was developed, validated, and applied to plasma samples from patients under
Autor:
Frank W. Lee, Chii-Ming Lai, C. Edwin Garner, Carl P. Decicco, Jianrong Lin, Kevin Jones, Shimoga R. Prakash, Huey-Shin Shen, Mingxin Qian, Eric Solon, Stephen E. Mercer, Gang Luo, Lian-Shen Gan, Thomas P. Maduskuie, Jingwu Duan
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(6)
The role of the intestine in the elimination of (2R)-2-{(3R)-3-amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide (DPC 333), a potent inhibitor of tissue necrosis factor alpha-converting enzyme, was i
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 12(9)
A sensitive and specific high-performance liquid chromatographic (HPLC) method with fluorescence detection was developed for the simultaneous determination of DuP 128 (N'-(2,4-difluorophenyl)-N-[5-(4,5-diphenyl-1H-imidazol-2-ylthio)p entyl]-N- hepthy
Autor:
Check Quon, Catherine R Anderson, Roger L. Williams, Gregory Bienvenu, G. Gil Clifton, Chii-Ming Lai, Eileen Cook, Prasad Turlapaty, Ramon Vargas, Susan Grandy, Nancy C. Sambol, J David Wallin, Gil McMahon
Publikováno v:
Clinical pharmacology and therapeutics. 47(6)
Nicardipine hydrochloride was administered intravenously to two groups of hypertensive patients: one group of 37 patients with mild to moderate hypertension and one group of 20 patients with severe hypertension. In the first group, doses of 0.5, 1, 2
Publikováno v:
Journal of Pharmaceutical Sciences. 72:556-559
The distribution of [14C]bretylium tosylate in the body and the relationship between tissue and plasma concentrations was determined following intravenous administration of the drug to Charles River rats. The renal excretion of bretylium was rapid in
Autor:
Martha A. Mooers, Dietmar M. Wagenknecht, Anton H. Amann, Chii-Ming Lai, David M. Baaske, Ying-Chi Lee, James E. Carter
Publikováno v:
American Journal of Health-System Pharmacy. 37:803-808
The stability of bretylium tosylate in 11 common large-volume parenteral solutions was studied. Two containers of each solution, one glass and one plastic (except for mannitol and sodium bicarbonate solutions, which were available in glass only), wer
Autor:
George C. Chao, Avraham Yacobi, Chii-Ming Lai, James E. Carter, Anton H. Amann, David M. Baaske, Burde L. Kamath, Roger G. Stoll
Publikováno v:
Journal of Pharmaceutical Sciences. 69:1077-1081
This investigation compared the bioavailability of chlorpheniramine and pseudoephedrine from a sustained-action capsule and a combination of two reference standard tablets in 24 normal human subjects. The capsule contained 8 mg of chlorpheniramine ma
Publikováno v:
Life Sciences. 33:1989-1994
Hydroxyethyl starch (HES) found in rat serum and spleeb after single and daily administrations of 0.9 g/kg for 1 week was characterized by gas-liquid chromatography. There was very little difference in the degree of substitution (D.S.) and molar subs
Autor:
Charles S Davis, Check Y. Sum, Chii-Ming Lai, Ronald Kartzinel, Avraham Yacobi, Herman F. Stampfli
Publikováno v:
Clinical Pharmacology and Therapeutics. 34:427-434
Esmolol is an ultra-short-acting beta blocker. Its kinetics was studied in eight healthy subjects after continuous intravenous infusion of 400 micrograms/kg/min over 2 hr. The concentrations of esmolol and its major metabolite, 3-[4-(2-hydroxy-3-[iso