Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chii Shyang Fong"'
Autor:
Jimmy A. Rotolo, Chii Shyang Fong, Sahra Bodo, Prashanth K.B. Nagesh, John Fuller, Thivashnee Sharma, Alessandra Piersigilli, Zhigang Zhang, Zvi Fuks, Vijay K. Singh, Richard Kolesnick
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndr
Externí odkaz:
https://doaj.org/article/76b420606de142dd89228218364193f3
Autor:
Chii Shyang Fong, Gregory Mazo, Tuhin Das, Joshua Goodman, Minhee Kim, Brian P O'Rourke, Denisse Izquierdo, Meng-Fu Bryan Tsou
Publikováno v:
eLife, Vol 5 (2016)
Mitosis occurs efficiently, but when it is disturbed or delayed, p53-dependent cell death or senescence is often triggered after mitotic exit. To characterize this process, we conducted CRISPR-mediated loss-of-function screens using a cell-based assa
Externí odkaz:
https://doaj.org/article/4bc88d57725342a5b066b276867ffedb
Autor:
Zvi Fuks, Richard Kolesnick, Vijay K. Singh, Prashanth K.B. Nagesh, Zhigang Zhang, Alessandra Piersigilli, Sahra Bodo, Thivashnee Sharma, Chii Shyang Fong, Jimmy A. Rotolo, John D. Fuller
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
JCI Insight
JCI Insight
After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndr
Publikováno v:
Molecular Biology of the Cell
Centriole-to-centrosome conversion (CCC) safeguards centriole homeostasis by coupling centriole duplication with segregation, and is essential for stabilization of mature vertebrate centrioles naturally devoid of the geometric scaffold or the cartwhe
Autor:
Hirohisa Masuda, Isabelle Jourdain, Ngang Heok Tang, Chii Shyang Fong, Takashi Toda, Masashi Yukawa
Publikováno v:
Bioscience, biotechnology, and biochemistry. 83(9)
Temperature-sensitive (ts) mutants provide powerful tools, thereby investigating cellular functions of essential genes. We report here a simple procedure to generate ts mutations using error-prone PCR in pcp1 that encodes a spindle pole body (SPB) co
Autor:
Ngang Heok Tang, Chii Shyang Fong, Masuda, Hirohisa, Jourdain, Isabelle, Yukawa, Masashi, Toda, Takashi
Temperature-sensitive (ts) mutants provide powerful tools for investigation of cellular functions of essential genes. We report here asimple procedure to generate ts mutations using error-prone PCR within pcp1 that encodes aspindle pole body (SPB) co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6845e9b224ebe37de5299623f3651d29
Autor:
Ngang Heok Tang, Hirohisa Masuda, Masashi Yukawa, Isabelle Jourdain, Takashi Toda, Chii Shyang Fong
The spindle pole body (SPB) in fungi is the equivalent of the animal centrosome. A number of previous studies have identified many, if not all, components of the SPB. The SPB is the structural platform for microtubule nucleation and plays important r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b533835ab275468b857801b9dbe66b
Publikováno v:
Developmental Cell. 30:238-245
Centrioles are 9-fold symmetric structures duplicating once per cell cycle. Duplication involves self-oligomerization of the centriolar protein SAS-6, but how the 9-fold symmetry is invariantly established remains unclear. Here, we found that SAS-6 a
Publikováno v:
Molecular Biology of the Cell
Wee1 is highly dynamic at the SPB during the G2/M transition. Wee1 accumulates at the nuclear face of the SPB when cyclin B–Cdc2 peaks at the SPB and disappears from the SPB during spindle assembly. This dynamic behavior of Wee1 at the SPB is impor
Fission yeast Pcp1 links polo kinase-mediated mitotic entry to γ-tubulin-dependent spindle formation
Publikováno v:
The EMBO Journal
The centrosomal pericentrin-related proteins play pivotal roles in various aspects of cell division; however their underlying mechanisms remain largely elusive. Here we show that fission-yeast pericentrin-like Pcp1 regulates multiple functions of the