Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chiho Shoda"'
Autor:
Deokho Lee, Yohei Tomita, Yukihiro Miwa, Hiromitsu Kunimi, Ayaka Nakai, Chiho Shoda, Kazuno Negishi, Toshihide Kurihara
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10140 (2024)
Hypoxia-inducible factors (HIFs) are transcriptional factors that function as strong regulators of oxygen homeostasis and cellular metabolisms. The maintenance of cellular oxygen levels is critical as either insufficient or excessive oxygen affects d
Externí odkaz:
https://doaj.org/article/c19d15c6073e4fec86023f7aff57fdb6
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/cde8f3c857914add8a03e17468a99667
Autor:
Shin-ichi Ikeda, Toshihide Kurihara, Xiaoyan Jiang, Yukihiro Miwa, Deokho Lee, Naho Serizawa, Heonuk Jeong, Kiwako Mori, Yusaku Katada, Hiromitsu Kunimi, Nobuhiro Ozawa, Chiho Shoda, Mari Ibuki, Kazuno Negishi, Hidemasa Torii, Kazuo Tsubota
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
he underlying mechanism of myopic axial elongation of the eyes has long been unknown. Here, the authors show that endoplasmic reticulum stress in the sclera and its sensor proteins, PERK and ATF6, are involved in myopic axial elongation
Externí odkaz:
https://doaj.org/article/abe2d08ccb054189bebfa5d5b0ad66d5
Autor:
Ayaka Nakai, Deokho Lee, Chiho Shoda, Kazuno Negishi, Hiroyuki Nakashizuka, Satoru Yamagami, Toshihide Kurihara
Publikováno v:
Journal of Ophthalmology, Vol 2023 (2023)
Background. Anti-vascular endothelial growth factor (anti-VEGF) therapy via intravitreal injection is an effective treatment for patients with abnormal ocular neovascularization, such as age-related macular degeneration (AMD) and diabetic macular ede
Externí odkaz:
https://doaj.org/article/b7df9caa4ceb4f2c9f6f9005c81766a2
Autor:
Mihaya Kotajima, Jae-Hoon Choi, Mitsuru Kondo, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Taro Yasuma, Esteban C. Gabazza, Yukihiro Miwa, Chiho Shoda, Deokho Lee, Ayaka Nakai, Toshihide Kurihara, Jing Wu, Hirofumi Hirai, Hirokazu Kawagishi
Publikováno v:
Molecules, Vol 27, Iss 24, p 8925 (2022)
Two compounds 1 and 2 were isolated from the culture broth of Lepista luscina. This is the first time that compound 1 was isolated from a natural source. The structure of compound 1 was identified via 1D and 2D NMR and HRESIMS data. Compounds 1 and 2
Externí odkaz:
https://doaj.org/article/f9ac355b8d67486cb29a7cfb208806e1
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundLactoferrin, a type of glycoprotein, is contained in exocrine fluids such as tears, breast milk, sweat, and saliva, and is known to have anti-microbial, antioxidant, and anti-cancer effects. In the ophthalmological field, topical administra
Externí odkaz:
https://doaj.org/article/40f73c7f177343d386120c1ee2250197
Autor:
Deokho Lee, Yukihiro Miwa, Jing Wu, Chiho Shoda, Heonuk Jeong, Hirokazu Kawagishi, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1405 (2020)
Neovascular retinal degeneration is a leading cause of blindness in advanced countries. Anti-vascular endothelial growth factor (VEGF) drugs have been used for neovascular retinal diseases; however, anti-VEGF drugs may cause the development of chorio
Externí odkaz:
https://doaj.org/article/432564d1af964581a69133d561c5a96d
Autor:
Chiho Shoda, Yukihiro Miwa, Kazumi Nimura, Kazutoshi Okamoto, Satoru Yamagami, Kazuo Tsubota, Toshihide Kurihara
Publikováno v:
Nutrients, Vol 12, Iss 4, p 1055 (2020)
Neovascular retinal degenerative diseases are the leading causes of blindness in developed countries. Anti-vascular endothelial growth factor (VEGF) therapy is commonly used to treat these diseases currently. However, recent reports indicate that lon
Externí odkaz:
https://doaj.org/article/65456ac3347b487caf4fb00104453428
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5049 (2019)
Background: Age-related macular degeneration (AMD) is the leading cause of blindness and can be classified into two types called atrophic AMD (dry AMD) and neovascular AMD (wet AMD). Dry AMD is characterized by cellular degeneration of the retinal pi
Externí odkaz:
https://doaj.org/article/92eea040505847bd89091830cc91fc4e
Autor:
Mari Ibuki, Deokho Lee, Hiromitsu Kunimi, Chiho Shoda, Ayaka Nakai, Toshihide Kurihara, Yukihiro Miwa
Publikováno v:
The Keio Journal of Medicine. 71:1-12
The uncontrolled growth of blood vessels is a major pathological factor in human eye diseases that can result in blindness. This effect is termed ocular neovascularization and is seen in diabetic retinopathy, age-related macular degeneration, glaucom