Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chiho Nagasawa"'
Autor:
Hiroko Endo, Junko Shinozaki, Kaori Miyamoto, Chiho Nagasawa, Hitoshi Watanabe, Shinobu Suzuki, Shota Saiki, Chiaki Nakamori, Kiyotaka Koyabu, Yayoi Honda, Chiaki Nakayama, Ikumi Washio, Takeshi Kunimatsu, Hisashi Nogawa, Hiroshi Iwasaki, Etsushi Takahashi, Yumiko Nozaki, Atsuhiro Yamanishi, Tetsuji Itoh
Publikováno v:
Regulatory Toxicology and Pharmacology. 77:75-86
In vitro screening of hERG channels are recommended under ICH S7B guidelines to predict drug-induced QT prolongation and Torsade de Pointes (TdP), whereas proarrhythmia is known to be evoked by blockage of other ion channels involved in cardiac contr
Autor:
Masanori Tohno, Takeshi Shimosato, Tadao Saito, Haruki Kitazawa, Junko Nishimura-Uemura, Munehiro Oda, Chiho Nagasawa, Shuji Ikegami, Yasushi Kawai
Publikováno v:
Asian-Australasian Journal of Animal Sciences. 23:106-115
Phosphorylated dextran (P-Dex) is an acidic polysaccharide that functions as an immune adjuvant. P-Dex is known to regulate immune response by maintaining a balance between Th1 and Th2 cells in vitro, and thus may also be important in the control of
Autor:
Kaori Miyamoto, Ikumi Washio, Hitoshi Watanabe, Chiaki Nakamori, Kohji Tanaka, Hiroshi Iwasaki, Atsuhiro Yamanishi, Kaoru Morimura, Yumiko Nozaki, Chiho Nagasawa, Shota Saiki, Chiaki Nakayama, Hisashi Nogawa, Takeshi Kunimatsu, Yayoi Honda, Etsushi Takahashi, Hiroko Endo, Shinobu Suzuki
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:385
Autor:
Iliyan D. Iliev, Takeshi Shimosato, Haruki Kitazawa, Shinichiro Katoh, Toshiro Kimura, Masanori Tohno, Chiho Nagasawa, Yasushi Kawai, Tadao Saito
Publikováno v:
Biochemical and biophysical research communications. 326(4)
Toll-like receptor 9, which is expressed on the surface of antigen presenting cells and which was recently identified in the cytoplasmic follicle, recognizes bacterial CpG oligodeoxynucleotides (ODNs), resulting in the induction of a potent immune re
Autor:
Tetsuo Kitamura, Seiji Hayashi, Atsuko Ojima, Chiaki Nakamori, Chiho Nagasawa, Kohei Sawada, Tomoharu Osada, Yasunari Kanda, Norimasa Miyamoto, Hiroyuki Ando, Chieko Kasai, Yayoi Honda, Keiichi Asakura, Tomohiko Taniguchi, Yuko Sekino
Publikováno v:
Journal of Pharmacological and Toxicological Methods. :17-26
Introduction Multi-electrode array (MEA) systems and human induced pluripotent stem (iPS) cell-derived cardiomyocytes are frequently used to characterize the electrophysiological effects of drug candidates for the prediction of QT prolongation and pr