Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chiho Minamitani"'
Autor:
Shinji Takai, Rie Matsushima-Nishiwaki, Seiji Adachi, Hideo Natsume, Chiho Minamitani, Jun Mizutani, Takanobu Otsuka, Haruhiko Tokuda, Osamu Kozawa
Publikováno v:
Mediators of Inflammation, Vol 2008 (2008)
We previously showed that the mitogen-activated protein (MAP) kinase superfamily, p44/p42 MAP kinase, p38 MAP kinase, and stress-activated protein kinase (SAPK)/c-Jun N-terminal (JNK), positively plays a part in the platelet-derived growth factor-BB-
Externí odkaz:
https://doaj.org/article/e6ae2c1af7334cacb6e0541db863dab7
Autor:
Takanobu Otsuka, Kenji Kato, Yasuo Katagiri, Haruhiko Tokuda, Rie Matsushima-Nishiwaki, Hideo Natsume, Seiji Adachi, Osamu Kozawa, Jun Mizutani, Yoshinobu Hirose, Chiho Minamitani
Publikováno v:
Endocrinology. 152:1872-1882
We have previously reported that various stimuli, including sphingosine 1-phosphate, are able to induce heat shock protein (HSP) 27 in osteoblast-like MC3T3-E1 cells. However, the precise role of HSP27 in bone metabolism has not been satisfactory cla
Autor:
Chiho Minamitani, Hideo Natsume, Rie Matsushima-Nishiwaki, Osamu Kozawa, Takanobu Otsuka, Seiji Adachi, Haruhiko Tokuda, Kenji Kato
Publikováno v:
Molecular and Cellular Endocrinology. 331:66-72
It is recognized that Wnt pathways regulate bone metabolism. We have previously shown that tumor necrosis factor-α (TNF-α) stimulates synthesis of interleukin-6 (IL-6), a potent bone resorptive agent, via p44/p42 mitogen-activated protein (MAP) kin
Autor:
Hisaaki Kato, Haruhiko Tokuda, Seiji Adachi, Shinji Ogura, Rie Matsushima-Nishiwaki, Tomoaki Doi, Osamu Kozawa, Chiho Minamitani, Yukiko Enomoto, Takanobu Otsuka, Shigeru Akamatsu, Toru Iwama
Publikováno v:
Thrombosis Research. 126:39-43
Collagen plays a crucial role in hemostasis and thrombosis by activating platelets and reportedly induces the phosphorylation of heat shock protein (HSP) 27 in human platelets. However, the exact role of HSP27 phosphorylation in human platelets has n
Autor:
Rie Matsushima-Nishiwaki, Haruhiko Tokuda, Junichi Yamauchi, Takanobu Otsuka, Osamu Kozawa, Chiho Minamitani, Kenji Kato, Seiji Adachi, Hideo Natsume, Jun Mizutani
Publikováno v:
Molecular and Cellular Endocrinology. 315:195-200
Our previous study demonstrated that tumor necrosis factor-alpha (TNF-alpha) stimulates the synthesis of interleukin-6 (IL-6), a potent bone resorptive agent, via p44/p42 mitogen-activated protein (MAP) kinase and phosphatidylinositol 3-kinase/Akt in
Autor:
Chiho Minamitani, Kenji Kato, Takanobu Otsuka, Rie Matsushima-Nishiwaki, Osamu Kozawa, Hideo Natsume, Jun Mizutani, Haruhiko Tokuda, Seiji Adachi
Publikováno v:
Experimental and Therapeutic Medicine. 1:579-583
We previously reported that prostaglandin D(2) (PGD(2)) stimulates heat shock protein 27 (HSP27) induction through p44/p42 mitogen-activated protein (MAP) kinase, p38 MAP kinase and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) i
Autor:
Seiji Adachi, Shinji Takai, Tomoaki Doi, Chiho Minamitani, Rie Matsushima-Nishiwaki, Hisaaki Kato, Haruhiko Tokuda, Toru Iwama, Yukiko Enomoto, Osamu Kozawa, Shinji Ogura, Takanobu Otsuka, Shigeru Akamatsu
Publikováno v:
Archives of Biochemistry and Biophysics. 489:62-67
Antithrombin III (AT-III), an anti-coagulant, has recently been reported to directly affect human platelet functions. However, the exact mechanism of AT-III in platelets remains to be clarified. We have previously shown that adenosine diphosphate (AD
Autor:
Jun Mizutani, Junichi Yamauchi, Chiho Minamitani, Shinji Takai, Takanobu Otsuka, Kanefusa Kato, Rie Matsushima-Nishiwaki, Seiji Adachi, Osamu Kozawa, Haruhiko Tokuda, Hideo Natsume
Publikováno v:
International Journal of Molecular Medicine. 24(2):197-203
We previously reported that sphingosine 1-phosphate stimulates the induction of heat shock protein 27 (HSP27) through p38 mitogen-activated protein (MAP) kinase and phosphatidylinositol 3-kinase/Akt in osteoblast-like MC3T3-E1 cells. In the present s
Autor:
Rie Matsushima-Nishiwaki, Yuji Kaneoka, Shinji Takai, Kanefusa Kato, Takahiro Noda, Seiji Adachi, Chiho Minamitani, Osamu Kozawa, Hidenori Toyoda, Akihiro Yamaguchi, Eisuke Yasuda, Takashi Kumada
Publikováno v:
Journal of Biological Chemistry. 283:18852-18860
Heat shock protein 27, one of the low molecular weight stress proteins, is recognized as a molecular chaperone; however, other functions have not yet been well established. Phosphorylated heat shock protein 27 levels inversely correlate with the prog
Autor:
Chiho Minamitani, Yoshiteru Hanai, Takanobu Otuka, Rie Matsushima-Nishiwaki, Shinji Takai, Osamu Kozawa, Haruhiko Tokuda
Publikováno v:
Internal Medicine. 47(17):1523-1528
A 59-year-old postmenopausal woman diagnosed to have primary osteoporosis began to take 60 mg daily of oral raloxifene. The platelet aggregation induced by 1 microM adenosine diphosphate (ADP) and the alpha2-antiplasmin activity were accelerated sign