Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chiho Hirata"'
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16259 (2011)
Humanin (HN), a 24-residue peptide, was identified as a novel neuroprotective factor and shows anti-cell death activity against a wide spectrum of Alzheimer's disease (AD)-related cytotoxicities, including exposure to amyloid beta (Abeta), in vitro.
Externí odkaz:
https://doaj.org/article/834c2ab3e3794cf1945c8f7335a9f5ea
Autor:
Shahin Imran, Masumi Oyama, Rie Horie, Natsuko I Kobayashi, Alex Costa, Ryosuke Kumano, Chiho Hirata, Sen Thi Huong Tran, Maki Katsuhara, Keitaro Tanoi, Takayuki Kohchi, Kimitsune Ishizaki, Tomoaki Horie
Publikováno v:
Plant and Cell Physiology (2022). doi:10.1093/pcp/pcac044
info:cnr-pdr/source/autori:Imran, S (Imran, Shahin) [1], [2] ; Oyama, M (Oyama, Masumi) [3] ; Horie, R (Horie, Rie) [3] ; Kobayashi, NI (Kobayashi, Natsuko, I) [4] ; Costa, A (Costa, Alex) [5], [6] ; Kumano, R (Kumano, Ryosuke) [3] ; Hirata, C (Hirata, Chiho) [7] ; Tran, STH (Sen Thi Huong Tran) [1], [8] ; Katsuhara, M (Katsuhara, Maki) [1] ; Tanoi, K (Tanoi, Keitaro) [4] ; Kohchi, T (Kohchi, Takayuki) [9] ; Ishizaki, K (Ishizaki, Kimitsune) [7] ; Horie, T (Horie, Tomoaki) [3]/titolo:Distinct Functions of the Atypical Terminal Hydrophilic Domain of the HKT Transporter in the Liverwort Marchantia polymorpha/doi:10.1093%2Fpcp%2Fpcac044/rivista:Plant and Cell Physiology/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Imran, S (Imran, Shahin) [1], [2] ; Oyama, M (Oyama, Masumi) [3] ; Horie, R (Horie, Rie) [3] ; Kobayashi, NI (Kobayashi, Natsuko, I) [4] ; Costa, A (Costa, Alex) [5], [6] ; Kumano, R (Kumano, Ryosuke) [3] ; Hirata, C (Hirata, Chiho) [7] ; Tran, STH (Sen Thi Huong Tran) [1], [8] ; Katsuhara, M (Katsuhara, Maki) [1] ; Tanoi, K (Tanoi, Keitaro) [4] ; Kohchi, T (Kohchi, Takayuki) [9] ; Ishizaki, K (Ishizaki, Kimitsune) [7] ; Horie, T (Horie, Tomoaki) [3]/titolo:Distinct Functions of the Atypical Terminal Hydrophilic Domain of the HKT Transporter in the Liverwort Marchantia polymorpha/doi:10.1093%2Fpcp%2Fpcac044/rivista:Plant and Cell Physiology/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
K+/Na+ homeostasis is important for land plants, particularly under salt stress. In this study, the structure and ion transport properties of the high-affinity K+ transporter (HKT) of the liverwort Marchantia polymorpha were investigated. Only one HK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610d4562d182522b007e2ead51d5d41a
https://doi.org/10.1093/pcp/pcac044
https://doi.org/10.1093/pcp/pcac044
Autor:
Chiho Hirata-Fukae, Tsutomu Hirata
Publikováno v:
Developmental Dynamics. 243:1030-1036
Background: The basolateral complex, comprised of the lateral, basolateral, and basomedial nuclei, is the main structure of the amygdala and contains two neuronal cell types: excitatory neurons and inhibitory interneurons. Studies show that most of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59452ee076316977deddb48b81057bf6
https://doi.org/10.1002/dvdy.24137
https://doi.org/10.1002/dvdy.24137
Autor:
Maxim Totrov, Yasuji Matsuoka, Chiho Hirata-Fukae, Paul R. Carlier, Christopher J. Monceaux, Polo C.-H. Lam
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:3992-3996
In the course of a β-site APP-cleaving enzyme 1 (BACE1) inhibitor discovery project an in situ synthesis/screening protocol was employed to prepare 120 triazole-linked reduced amide isostere inhibitors. Among these compounds, four showed modest (sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a37287b3006427849b63b809c00feea
https://doi.org/10.1016/j.bmcl.2011.05.007
https://doi.org/10.1016/j.bmcl.2011.05.007
Autor:
Audrey J. Gray, Saori Chishiro, Gaku Sakaguchi, Yasuji Matsuoka, Paul S. Aisen, Chiho Hirata-Fukae, Amanda G. Becker, Yoshihisa Kitamura, Akira Kato, Kazuyuki Takata, Frank M. LaFerla, Kouhei Nishitomi, Mark P. Mattson, Andreas H. Franz
Publikováno v:
European Journal of Neuroscience. 26:2458-2468
Accumulation of amyloid beta (Abeta) is a pathological hallmark of Alzheimer's disease, and lowering Abeta is a promising therapeutic approach. Intact anti-Abeta antibodies reduce brain Abeta through two pathways: enhanced microglial phagocytosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1062204bf2f92799d54f2d7b579dc18b
https://doi.org/10.1111/j.1460-9568.2007.05852.x
https://doi.org/10.1111/j.1460-9568.2007.05852.x
Autor:
Audrey J. Gray, Illana Gozes, S. Sakura Minami, Mark P. Mattson, Paul S. Aisen, Emily G. Waterhouse, Frank M. LaFerla, Chiho Hirata-Fukae, Yasuji Matsuoka
Publikováno v:
Journal of Molecular Neuroscience. 31:165-170
Accumulation of β-amyloid (Aβ) peptide and hyperphosphorylation of tau in the brain are pathological hallmarks of Alzheimer’s disease (AD). Agents altering these pathological events might modify clinical disease progression. NAP (Asn-Ala-Pro-Val-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1aa322812c980380ef47f2a0bc951
https://doi.org/10.1385/jmn/31:02:165
https://doi.org/10.1385/jmn/31:02:165
Autor:
Audrey J. Gray, Yuko Horikoshi, Yoshihiro Nakajima, Chie Takeyama, Kouhei Nishitomi, Motoko Hosono, Isako Sakaguchi, Paul S. Aisen, Gaku Sakaguchi, Akinobu Ota, Hui Fang Li, Yasuji Matsuoka, Philip C. Wong, Amanda G. Becker, S. Sakura Minami, Chiho Hirata-Fukae, Tsuyoshi Kihara, Akira Kato, Noriaki Kinoshita, Masahiro Maeda
Publikováno v:
Journal of Neurochemistry. 99:1555-1563
Accumulation of amyloid beta peptide (Abeta) in brain is a hallmark of Alzheimer's disease (AD). Inhibition of beta-site amyloid precursor protein (APP)-cleaving enzyme-1 (BACE1), the enzyme that initiates Abeta production, and other Abeta-lowering s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab1d96a723005ea0f5b01279733f7e7
https://doi.org/10.1111/j.1471-4159.2006.04178.x
https://doi.org/10.1111/j.1471-4159.2006.04178.x
Autor:
Chiho, Hirata-Fukae, Tsutomu, Hirata
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 243(8)
The basolateral complex, comprised of the lateral, basolateral, and basomedial nuclei, is the main structure of the amygdala and contains two neuronal cell types: excitatory neurons and inhibitory interneurons. Studies show that most of the excitator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd68fa2ab94e69bb3fd3f61967cc2212
https://pubmed.ncbi.nlm.nih.gov/24723342
https://pubmed.ncbi.nlm.nih.gov/24723342
Autor:
Paul S. Aisen, Yasuji Matsuoka, Chiho Hirata-Fukae, Li Ma, G. William Rebeck, Hui Fang Li, Hyang-Sook Hoe
Publikováno v:
Neuroscience letters. 450(1)
The clinical progression of Alzheimer's disease is closely related to tau pathology. Hyperphosphorylation of tau precedes histopathological evidence of tangle formation, and modulation of tau phosphorylation is a promising therapeutic target. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31571d46e41ada57f9311ced3c5d038
https://pubmed.ncbi.nlm.nih.gov/19022346
https://pubmed.ncbi.nlm.nih.gov/19022346
Autor:
Ottavio Arancio, Yasuji Matsuoka, Benjamin R Walker, Illana Gozes, Paul S. Aisen, Yan Jouroukhin, Emmanuel Planel, Audrey J. Gray, Li Feng, Laurent Lecanu, Li Ma, Hui Fang Li, Chiho Hirata-Fukae
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 325(1)
Neurofibrillary tangles composed of aggregated, hyperphosphorylated tau in an abnormal conformation represent one of the major pathological hallmarks of Alzheimer's disease (AD) and other tauopathies. However, recent data suggest that the pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef7260e87a462c955f1b8d7c2294c18
https://pubmed.ncbi.nlm.nih.gov/18199809
https://pubmed.ncbi.nlm.nih.gov/18199809