Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chihiro Yokoo"'
Publikováno v:
The Journal of Organic Chemistry. 59:7499-7502
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::292e99798c08f0745d245f34c59c5f65
https://doi.org/10.1021/jo00103a053
https://doi.org/10.1021/jo00103a053
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 49:993-996
The orientations of the carbonyl groups at C3 and C5 are different. The phenyl ring linked to C4 is perpendicular to the dihydropyridine ring. Some other structural features have also been elucidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c25586fcdc03f4e6d937ba70142e2b7
https://doi.org/10.1107/s0108270192012447
https://doi.org/10.1107/s0108270192012447
Publikováno v:
ChemInform. 24
Enantiomeric (+)- and (–)-methy3-nitrooxypropyl 1,4-dihydro-2,6-dimethyl-4-(3- nitrophenyl) pyridine-3,5-dicarboxylate 1 were synthesized by esterification of the optically active monocarboxylic acids (+)-6 and (–)-6, which are available from rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f1be712a8ef2de87143a7c7dc514223
https://doi.org/10.1002/chin.199323202
https://doi.org/10.1002/chin.199323202
Autor:
Chihiro Yokoo, Shigeyuki Sumiya, Masaharu Tamai, Kunihiro Kitamura, Mitsuo Murata, Atsushi Yamamoto, Teruyo Yoneda, Toshimasa Ishida, Masatoshi Inoue
Publikováno v:
Chemical and Pharmaceutical Bulletin. 40:299-303
To design a potent inhibitor specific for cathepsin B (rat liver), the tertiary structure was predicted based on the crystal structure of the papain complexed with (+)-(2S,3S)-3-(1-[N-(3-methylbutyl)amino]leucylcarbonyl)oxirane-2- carbolylic acid (E-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95b18818dd460f2f0c2b43260e49395
https://doi.org/10.1248/cpb.40.299
https://doi.org/10.1248/cpb.40.299
Autor:
Masaharu Tamai, Takeshi Nikawa, Kazunori Hanada, Chihiro Yokoo, Nobuhiko Katunuma, Takae Towatari, Mitsuo Murata
Publikováno v:
FEBS Letters. 280:311-315
New derivatives of E-64 (compound CA-030 and CA-074) were tested in vitro and in vivo for selective inhibition of cathepsin B. They exhibited 10000–30000 times greater inhibitory effects on purified rat cathepsin B than on cathepsin H and L; their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c7b45345587986c936dacf5ceadd25
https://doi.org/10.1016/0014-5793(91)80319-x
https://doi.org/10.1016/0014-5793(91)80319-x
Autor:
Takeshi Nikawa, Takae Towatari, Satsuki Miyashita, Nobuhiko Katunuma, Mitsuo Murata, Musaharu Tamai, Chihiro Yokoo, Katsuo Hatayama, Kazunori Hanada
Publikováno v:
FEBS Letters. 280:307-310
A series of new epoxysuccinyl peptides were designed and synthesized to develop a specific inhibitor of cathepsin B. Of these compounds, N-(L-3-trans-ethoxycarbonyloxirane-2-carbonyl)-L-isoleucyl-L-proline (compound CA-030) and N-(L-3-trans-propylcar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb62e15e775b687551063f5a2c4c4a09
https://doi.org/10.1016/0014-5793(91)80318-w
https://doi.org/10.1016/0014-5793(91)80318-w
Publikováno v:
The Journal of antibiotics. 45(9)
A series of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido] cephalosporins (1) having various substituted alkylthio groups at the C-3 position of the cephem nucleus were prepared and evaluated for antibacterial activity and oral ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7c63d629f0f9f6befdda92a996fddb
https://pubmed.ncbi.nlm.nih.gov/1429240
https://pubmed.ncbi.nlm.nih.gov/1429240
Publikováno v:
The Journal of antibiotics. 44(12)
A series of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(carboxymethoxyimino)ace tamido] cephalosporins (1) having various substituted-vinylthio groups at the C-3 position of the cephen nucleus was synthesized and evaluated for antibacterial activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1bba3a9521e298582b0ace0db64524
https://pubmed.ncbi.nlm.nih.gov/1778793
https://pubmed.ncbi.nlm.nih.gov/1778793
Publikováno v:
The Journal of antibiotics. 44(5)
The synthesis, antibacterial activity and oral absorption in rats of new 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(carboxymethoxyimino)ace tamido] cephalosporins (1) having various substituted-alkylthio groups at the C-3 position of the cephem nucleus a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8602930d45c9548968e6864233b1d2aa
https://pubmed.ncbi.nlm.nih.gov/2061193
https://pubmed.ncbi.nlm.nih.gov/2061193
Autor:
Shouta Taira, Hiroaki Miyaoka, Hidemichi Mitome, Chihiro Yokoo, Kazuo Iguchi, Keita Matsumoto, Yasuji Yamada
Publikováno v:
Chemistry Letters. 25:239-240
Two new cembrane-type diterpenoids, sarcodiol (1) and 3,4-epoxysarcophytonin (4), were isolated from Okinawan soft coral of the genus, Sarcophyton. Their structures were determined from spectroscopic measurements, X-ray analysis and chemical reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdda682cd9842aeeb960e529286e1bbe
https://doi.org/10.1246/cl.1996.239
https://doi.org/10.1246/cl.1996.239