Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Chihiro MOGI"'
Autor:
Masayuki Oginuma, Moana Nishida, Tomomi Ohmura-Adachi, Kota Abe, Shohei Ogamino, Chihiro Mogi, Hideaki Matsui, Tohru Ishitani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The African turquoise killifish Nothobranchius furzeri (N. furzeri) is a useful model organism for studying aging, age-related diseases, and embryonic diapause. CRISPR/Cas9-mediated gene knockout and Tol2 transposon-mediated transgenesis in
Externí odkaz:
https://doaj.org/article/14c260ed3df0485bbf5fa740db5daca8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
It is unclear how a single oncogenic cell primes tumorigenesis. Here the authors visualised this behaviour using a zebrafish larval skin as a model and show that RasG12V oncogenic cell is eliminated through oncogene-senescence while a gain of functio
Externí odkaz:
https://doaj.org/article/c9be9250be8d47abbb6730e2f4974c7e
Autor:
Shiori MUSHA, Saishu YOSHIDA, Syo MURAKAMI, Ryotaro KOJIMA, Masahito DEAI, Naoshi SASO, Chihiro MOGI, Koichi SATO, Fumikazu OKAJIMA, Hideaki TOMURA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 2, Pp 175-180 (2020)
Hormone-secreting pituitary adenomas show unregulated hormonal hypersecretion and cause hyperpituitarism. However, the mechanism of the unregulated hormone production and secretion has not yet been fully elucidated. Solid tumors show reduced extracel
Externí odkaz:
https://doaj.org/article/319d50874f4241558f6c85e2aa75eb3a
Autor:
Akiomi Nagasaka, Chihiro Mogi, Hiroki Ono, Toshihide Nishi, Yuma Horii, Yuki Ohba, Koichi Sato, Michio Nakaya, Fumikazu Okajima, Hitoshi Kurose
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Myocardial infarction (MI) is an ischaemic heart condition caused by the occlusion of coronary arteries. Following MI, lactic acid from anaerobic glycolysis increases and infiltrating immune cells produce severe inflammation, which leads to
Externí odkaz:
https://doaj.org/article/79bdd7ecb0b44afb8eab5d5cabbfc604
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178769 (2017)
Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1-7 and alamandine are heptameric renin angiotensin system peptide hormones. Further, alamandine levels increase with renal dysfunctio
Externí odkaz:
https://doaj.org/article/c9866bd35867422cb63cb499ee636098
Autor:
Ayaka Tobo, Masayuki Tobo, Takashi Nakakura, Masashi Ebara, Hideaki Tomura, Chihiro Mogi, Dong-Soon Im, Naoya Murata, Atsushi Kuwabara, Saki Ito, Hayato Fukuda, Mitsuhiro Arisawa, Satoshi Shuto, Michio Nakaya, Hitoshi Kurose, Koichi Sato, Fumikazu Okajima
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129334 (2015)
G protein-coupled receptor 4 (GPR4), previously proposed as the receptor for sphingosylphosphorylcholine, has recently been identified as the proton-sensing G protein-coupled receptor (GPCR) coupling to multiple intracellular signaling pathways, incl
Externí odkaz:
https://doaj.org/article/9cf59e4d2f3f49efb7bde40467363339
Autor:
Chihiro Mogi, Hideaki Tomura, Masayuki Tobo, Ju-Qiang Wang, Alatangaole Damirin, Junko Kon, Mayumi Komachi, Kinji Hashimoto, Koichi Sato, Fumikazu Okajima
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 2, Pp 160-167 (2005)
Ovarian cancer G-protein-coupled receptor 1 (OGR1), previously proposed as a receptor for sphingosylphosphorylcholine (SPC), has recently been identified as a proton-sensing or extracellular pH-responsive G-protein-coupled receptor stimulating inosit
Externí odkaz:
https://doaj.org/article/3d3da63358de4bdd9feb724c53f0eda3
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
An acidic microenvironment has been shown to evoke a variety of airway responses, including cough, bronchoconstriction, airway hyperresponsiveness (AHR), infiltration of inflammatory cells in the lung, and stimulation of mucus hyperproduction. Except
Externí odkaz:
https://doaj.org/article/120aad5f697a48f8bbd117288f610854
Autor:
Haruka Aoki, Chihiro Mogi, Takeshi Hisada, Takashi Nakakura, Yosuke Kamide, Isao Ichimonji, Hideaki Tomura, Masayuki Tobo, Koichi Sato, Hiroaki Tsurumaki, Kunio Dobashi, Tetsuya Mori, Akihiro Harada, Masanobu Yamada, Masatomo Mori, Tamotsu Ishizuka, Fumikazu Okajima
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79985 (2013)
Ovarian cancer G protein-coupled receptor 1 (OGR1) stimulation by extracellular protons causes the activation of G proteins and subsequent cellular functions. However, the physiological and pathophysiological roles of OGR1 in airway responses remain
Externí odkaz:
https://doaj.org/article/a5b9f70e2daf4200a9b57ad3d3892858
Autor:
Nobuhiro Yamane, Fumikazu Okajima, Dong Soon Im, Koichi Sato, Masayuki Tobo, Ayaka Tobo, Hideaki Tomura, Chihiro Mogi, Masahiko Tosaka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Extracellular acidification in the brain has been observed in ischemia; however, the physiological and pathophysiological implications of the pH reduction remain largely unknown. Here, we analyzed the roles of proton-sensing G protein-coupled recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfab8adae0bf799563961209edde636
http://link.springer.com/article/10.1038/s41598-020-74372-7
http://link.springer.com/article/10.1038/s41598-020-74372-7