Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chihiro Higuchi"'
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
Optimizing and automating a protocol for 16S microbiome data analysis with QIIME2 is a challenging task. It involves a multi-step process, and multiple parameters and options that need to be tested and determined. In this article, we describe Snaq, a
Externí odkaz:
https://doaj.org/article/ca02dad871fc4ee993941b8dfda2fee5
Autor:
Yuki Nagata, Ryo Watanabe, Christian Eichhorn, Seiko Ohno, Takeshi Aiba, Taisuke Ishikawa, Yukiko Nakano, Yoshiyasu Aizawa, Kenshi Hayashi, Nobuyuki Murakoshi, Tadashi Nakajima, Nobue Yagihara, Hiroyuki Mishima, Takeaki Sudo, Chihiro Higuchi, Atsushi Takahashi, Akihiro Sekine, Takeru Makiyama, Yoshihiro Tanaka, Atsuyuki Watanabe, Motomi Tachibana, Hiroshi Morita, Koh-Ichiro Yoshiura, Tatsuhiko Tsunoda, Hiroshi Watanabe, Masahiko Kurabayashi, Akihiko Nogami, Yasuki Kihara, Minoru Horie, Wataru Shimizu, Naomasa Makita, Toshihiro Tanaka
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0277242 (2022)
Long QT syndrome (LQTS) is one of the most common inherited arrhythmias and multiple genes have been reported as causative. Presently, genetic diagnosis for LQTS patients is becoming widespread and contributing to implementation of therapies. However
Externí odkaz:
https://doaj.org/article/a19e4953468f4fa0aebed8e4a9b0d33a
Autor:
Yi-An Chen, Erika Yogo, Naoko Kurihara, Tomoshige Ohno, Chihiro Higuchi, Masatomo Rokushima, Kenji Mizuguchi
Publikováno v:
F1000Research, Vol 8 (2019)
In selecting drug target candidates for pharmaceutical research, the linkage to disease and the tractability of the target are two important factors that can ultimately determine the drug efficacy. Several existing resources can provide gene-disease
Externí odkaz:
https://doaj.org/article/f618b3fab7cc47e3b9e32110116856e6
Autor:
Yi-An Chen, Erika Yogo, Naoko Kurihara, Tomoshige Ohno, Chihiro Higuchi, Masatomo Rokushima, Kenji Mizuguchi
Publikováno v:
F1000Research, Vol 8 (2019)
In selecting drug target candidates for pharmaceutical research, the linkage to disease and the tractability of the target are two important factors that can ultimately determine the drug efficacy. Several existing resources can provide gene-disease
Externí odkaz:
https://doaj.org/article/d2ab4eb6c71b429a85578a1d4f49b45d
Autor:
Yayoi Natsume-Kitatani, Mari N Itoh, Yoshito Takeda, Masataka Kuroda, Haruhiko Hirata, Kohtaro Miyake, Takayuki Shiroyama, Yuya Shirai, Yoshimi Noda, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Jun Adachi, Ryohei Narumi, Satoshi Muraoka, Takeshi Tomonaga, Sadao Kurohashi, Fei Cheng, Ribeka Tanaka, Shuntaro Yada, Eiji Aramaki, Shoko Wakamiya, Yi-An Chen, Chihiro Higuchi, Yosui Nojima, Takeshi Fujiwara, Chioko Nagao, Toshihiro Takeda, Yasushi Matsumura, Kenji Mizuguchi, Atsushi Kumanogoh, Naonori Ueda
Medical information is valuable information obtained from humans regarding the phenotype of diseases. Omics data is informative to understand diseases at biomolecular level. We aimed to detect patient stratification patterns in a data-driven manner a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a92f5a70e3cf8d59b37f8bc806297d
https://doi.org/10.21203/rs.3.rs-405195/v3
https://doi.org/10.21203/rs.3.rs-405195/v3
Autor:
Kenji Mizuguchi, Yi-An Chen, Naoko Kurihara, Chihiro Higuchi, Masatomo Rokushima, Tomoshige Ohno, Erika Yogo
Publikováno v:
F1000Research
In selecting drug target candidates for pharmaceutical research, the linkage to disease and the tractability of the target are two important factors that can ultimately determine the drug efficacy. Several existing resources can provide gene-disease
Autor:
Katsuki Nakamura, Kenji Oeda, Kayo Sumida, Toru Yamada, Chihiro Higuchi, Keiko Nakagaki, Toshifumi Fukuoka, Koichi Saito, Shinichi Kohsaka
Publikováno v:
Neuroscience Research. 66:62-85
To facilitate common marmoset brain research, we produced a DNA microarray with 7557 probe sets derived from the common marmoset brain. Gene expression profiles in the frontal lobe, hippocampus, cerebellum and amygdaloid nucleus were then analyzed an
Publikováno v:
Bioinformatics and Biomedical Engineering ISBN: 9783319164793
IWBBIO (2)
IWBBIO (2)
Micro RNA (miRNA) plays important roles in a variety of biological processes and can act as disease biomarkers. Thus, establishment of discovery methods to detect disease-related miRNAs is warranted. Human omics data including miRNA expression profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e42fb937bc9776647e64ea7251d737d
https://doi.org/10.1007/978-3-319-16480-9_38
https://doi.org/10.1007/978-3-319-16480-9_38
Autor:
Ryoko Ohno, Masato Sudo, Hiroshi Sato, Yukako Sasaki, Shinji Takai, Kazuo Suzuki, Tsutomu Kakuda, Ken Maeda, Chihiro Higuchi, Mizuki Sakai
Publikováno v:
Journal of wildlife diseases. 48(3)
Rhodococcus equi was isolated from the submaxillary lymph nodes of wild boars (Sus scrofa) in Wakayama and Hyogo, Japan, with a high prevalence. Rhodococcus equi isolation rates between locations, sexes, or body weights were not different, except in
Publikováno v:
Journal of Heterocyclic Chemistry. 21:345-347
From the rate constants of the reaction with pyrrolidine, the reactivities of 3-(1-azolyl)-2-alken-1-ones with nucleophiles were evaluated to be rather high. Especially the reactivities of the quaternary salts of 3-(1-imidazolyl)-2-alken-1-ones were