Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Chihiro, Yamazaki"'
Autor:
Yu Kato, Chiaki Kajiwara, Ikuo Ishige, Shusaku Mizukami, Chihiro Yamazaki, Shingo Eikawa, Kazuhiro Kakimi, Heiichiro Udono
Publikováno v:
Autoimmune Diseases, Vol 2012 (2012)
Antigens (Ag) from cancer or virus-infected cells must be internalized by dendritic cells (DCs) to be presented to CD8+ T cells, which eventually differentiate into Ag-specific cytotoxic T lymphocytes (CTLs) that destroy cancer cells and infected cel
Externí odkaz:
https://doaj.org/article/ce7c4d89d0ea48db9aac4f95e1c1ef47
Autor:
Sumie Kashiwa, Seigo Amachi, Shigeki Yamamura, Yasuhiro Kasahara, Ayaka Horiuchi, Chihiro Yamazaki
Publikováno v:
Environmental microbiologyReferences. 22(6)
Pseudomonas sp. strain SCT is capable of using iodate (IO3 - ) as a terminal electron acceptor for anaerobic respiration. A possible key enzyme, periplasmic iodate reductase (Idr), was visualized by active staining on non-denaturing gel electrophores
Autor:
Chihiro Yamazaki, Takeshi Hirata, Hiromi Kumon, Masami Watanabe, Motoo Araki, Takuya Sadahira, Yuichi Ariyoshi, Yasutomo Nasu, Shingo Eikawa, Shin Ebara, Heiichiro Udono
Publikováno v:
Gene Therapy. 23:408-414
An adenovirus vector carrying the human Reduced Expression in Immortalized Cell (REIC)/Dkk-3 gene (Ad-REIC) mediates simultaneous induction of cancer-selective apoptosis and augmentation of anticancer immunity. In our preclinical and clinical studies
Autor:
Shusaku Mizukami, Heiichiro Udono, Mikako Nishida, Shingo Eikawa, Chihiro Yamazaki, Eiichi Nakayama
Publikováno v:
Proceedings of the National Academy of Sciences. 112:1809-1814
Metformin, a prescribed drug for type 2 diabetes, has been reported to have anti-cancer effects; however, the underlying mechanism is poorly understood. Here we show that this mechanism may be immune-mediated. Metformin enabled normal but not T-cell-
Autor:
Chihiro Yamazaki, Tsuneyasu Kaisho, Takeshi Hirashima, Izumi Sasaki, Mikako Nobuoka, Takashi Tanaka, Akihiko Iizuka, Eri Hamada, Tomokazu Ohta, Takahiro Yano, Katsuaki Sato, Hiroaki Hemmi, Yuri Fukuda, Masanaka Sugiyama, Katsuaki Hoshino
Publikováno v:
The Journal of Immunology. 190:6071-6082
Dendritic cells (DCs) consist of various subsets that play crucial roles in linking innate and adaptive immunity. In the murine spleen, CD8α+ DCs exhibit a propensity to ingest dying/dead cells, produce proinflammatory cytokines, and cross-present A
Autor:
Ken Ishii, Izumi Sasaki, Masanaka Sugiyama, Yuri Fukuda, Takashi Orimo, Tsuneyasu Kaisho, Florent Ginhoux, Soichiro Okura, Hiroaki Hemmi, Katsuaki Hoshino, Chihiro Yamazaki, Tomokazu Ohta
Publikováno v:
Scientific Reports
Intestinal immune homeostasis requires dynamic crosstalk between innate and adaptive immune cells. Dendritic cells (DCs) exist as multiple phenotypically and functionally distinct sub-populations within tissues, where they initiate immune responses a
Publikováno v:
FEMS Microbiology Letters. 311:10-17
Vibrio parahaemolyticus, one of the human pathogenic vibrios, causes gastroenteritis, wound infections and septicemia. Genomic sequencing of this organism revealed that it has two distinct type III secretion systems (T3SS1 and T3SS2). T3SS1 plays a s
Autor:
Tsuneyasu Kaisho, Izumi Sasaki, Hitoshi Kikutani, Takahiro Sugiyama, Teruhito Yasui, Takahiro Yano, Katsuaki Hoshino, Chihiro Yamazaki
Publikováno v:
The Journal of Immunology. 184:3341-3345
A plasmacytoid dendritic cell (DC) can produce large amounts of type I IFNs after sensing nucleic acids through TLR7 and TLR9. IκB kinase α (IKKα) is critically involved in this type I IFN production through its interaction with IFN regulatory fac
Autor:
Chihiro Yamazaki, Masayasu Yoshino, Masanori Naitou, Takeshi Kurama, Akira Suwa, Shunichiro Matsumoto, Rie Fujikawa, Ichiro Aramori, Teruhiko Shimokawa
Publikováno v:
FEBS Journal. 277:677-686
The aim of this study is to discover and characterize novel energy homeostasis-related molecules. We screened stock mouse embryonic stem cells established using the exchangeable gene trap method, and examined the effects of deficiency of the target g
Autor:
Hideyuki Katori, Masaru Shimada, Tohru Funahashi, Yasuko Nakano, Chihiro Yamazaki, Kenmei Takaichi, Keitaro Yokoyama, Fumi Takemoto, Shohei Nakanishi, Kenzo Kodaka, Tatsuya Suwabe, Junichi Hoshino, Naoki Sawa, Shigeyuki Arai, Akira Yamada, Seiichi Fukuda, Shunya Uchida, Yoshifumi Ubara
Publikováno v:
Nephron Clinical Practice. 111:c12-c20
Background/Aim: Plasma adiponectin may play a protective role in the pathogenesis of cardiovascular disease in hemodialysis (HD) patients. We examined the effect of plasma adiponectin levels on the prognosis of the HD patients. Methods: 68 HD patient