Zobrazeno 1 - 10
of 12
pro vyhledávání: '"ChihKai Chang"'
Autor:
Lin Wei Tung, Elena Groppa, Hesham Soliman, Bruce Lin, Chihkai Chang, Chun Wai Cheung, Morten Ritso, David Guo, Lucas Rempel, Sarthak Sinha, Christine Eisner, Julyanne Brassard, Kelly McNagny, Jeff Biernaskie, Fabio Rossi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Therapeutic angiogenesis represents a promising avenue to revascularize the ischemic heart. Its limited success is partly due to our poor understanding of the cardiac stroma, specifically mural cells, and their response to ischemic injury. H
Externí odkaz:
https://doaj.org/article/c7cb39f87ce94ef288a0066b7c125f46
Autor:
Elena Groppa, Paolo Martini, Nima Derakhshan, Marine Theret, Morten Ritso, Lin Wei Tung, Yu Xin Wang, Hesham Soliman, Mark Stephen Hamer, Laura Stankiewicz, Christine Eisner, Le Nevé Erwan, Chihkai Chang, Lin Yi, Jack H. Yuan, Sunny Kong, Curtis Weng, Josephine Adams, Lucas Chang, Anne Peng, Helen M. Blau, Chiara Romualdi, Fabio M.V. Rossi
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112051- (2023)
Summary: Efficient regeneration requires multiple cell types acting in coordination. To better understand the intercellular networks involved and how they change when regeneration fails, we profile the transcriptome of hematopoietic, stromal, myogeni
Externí odkaz:
https://doaj.org/article/c12b05e6be8a435eb48dd8d1046c9e9f
Autor:
Laura Mathä, Mónica Romera-Hernández, Catherine A. Steer, Yi Han Yin, Mona Orangi, Hanjoo Shim, ChihKai Chang, Fabio M. Rossi, Fumio Takei
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Group 2 innate lymphoid cells (ILC2s) are tissue resident in the lung and activated by inhaled allergens via epithelial-derived alarmins including IL-33. Activated ILC2s proliferate, produce IL-5 and IL-13, and induce eosinophilic inflammation. Here,
Externí odkaz:
https://doaj.org/article/9fbac660b3204eff83affd0eccc47ea7
Autor:
Nasim Kajabadi, Marcela Low, Erik Jacques, Heta Lad, Lin Wei Tung, Farshad Babaeijandaghi, Daniel Gamu, Diego Zelada, Chi Kin Wong, Chihkai Chang, Lin Yi, Michael N. Wosczyna, Thomas A. Rando, Juan Pablo Henríquez, William T. Gibson, Penney M. Gilbert, Fabio M.V. Rossi
Publikováno v:
Developmental Cell. 58:489-505.e7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8d012e1bd144c88acb888656f4087ed
https://doi.org/10.1016/j.devcel.2023.02.009
https://doi.org/10.1016/j.devcel.2023.02.009
Autor:
Wu A, Marine Theret, Osvaldo Contreras, ChihKai Chang, Li Ff, Tung Lw, Rempel L, Marcela Low, Fabio M.V. Rossi, Hesham Soliman
AimFibrosis is the most common complication from chronic diseases, and yet no therapy capable of mitigating its effects is available. Our goal is to unveil specific signallings regulating the fibrogenic process and to identify potential small molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1d89c14e55d3a6c2b4092d7894037f
https://doi.org/10.1101/2021.01.20.427485
https://doi.org/10.1101/2021.01.20.427485
Autor:
Martin Arostegui, Wilder Scott, Christina E. Barkauskas, Fabio M.V. Rossi, ChihKai Chang, Marcela Low, Kathleen M. MacLeod, Ben Paylor, T. Michael Underhill, Alessandra Rampazzo, Paola Braghetta, Dario R. Lemos, Hesham Soliman, Vendula Pospichalova, Daniela Fiore, Christina W. Lee, Vladimir Korinek
The cardiac stroma contains multipotent mesenchymal progenitors. However, lineage relationships within cardiac stromal cells are still poorly understood. Here, we identify heart-resident PDGFRa+Sca-1+cells as cardiac Fibro/Adipogenic Progenitors (cFA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f10a0991d1d93c5ea946d95618de318
http://hdl.handle.net/11577/3330750
http://hdl.handle.net/11577/3330750
Autor:
Lin Wei Tung, Hesham Soliman, Fabio M.V. Rossi, Lucas Rempel, Andrew Wu, Fang Fang Li, Marcela Low, Osvaldo Contreras, Marine Theret, ChihKai Chang
Publikováno v:
Life Sciences. 279:119482
Aim Fibrosis is the most common complication from chronic diseases, and yet no therapy capable of mitigating its effects is available. Our goal is to unveil specific signaling regulating the fibrogenic process and to identify potential small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f990f5812871b9bf2d1985ed009533e9
https://doi.org/10.1016/j.lfs.2021.119482
https://doi.org/10.1016/j.lfs.2021.119482
Autor:
ChihKai Chang, Elena Groppa, Gabrielle Johnston, Fabio M.V. Rossi, Lin Wei Tung, Michael Cummings, Christine Eisner
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchReferences. 35(8)
Acquired heterotopic ossifications (HO) arising as a result of various traumas, including injury or surgical interventions, often result in pain and loss of motion. Though triggers for HO have been identified, the cellular source of these heterotopic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295fc44808dac3a0c0af6e1faefa8bd6
https://pubmed.ncbi.nlm.nih.gov/32251540
https://pubmed.ncbi.nlm.nih.gov/32251540
Autor:
Anuradha Natarajan, Daniela Fiore, Regan-Heng Zhang, ChihKai Chang, Fabio M.V. Rossi, Sunny Lee, Farshad Babaeijandaghi, Sergei A. Nedospasov, Marcela Low, Dario R. Lemos
Publikováno v:
Nature Medicine. 21:786-794
Depending on the inflammatory milieu, injury can result either in a tissue's complete regeneration or in its degeneration and fibrosis, the latter of which could potentially lead to permanent organ failure. Yet how inflammatory cells regulate matrix-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4301ea28b02613f5e5ededae04ccd494
https://doi.org/10.1038/nm.3869
https://doi.org/10.1038/nm.3869
Autor:
Arthur V. Sampaio, Fabio M.V. Rossi, T. Michael Underhill, Dario R. Lemos, ChihKai Chang, Benjamin Paylor
Publikováno v:
Stem Cells. 30:1152-1162
Pathologies characterized by lipomatous infiltration of craniofacial structures as well as certain forms of lipodystrophies suggest the existence of a distinct adipogenic program in the cephalic region of mammals. Using lineage tracing, we studied th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fad5aa9ec9afc5441f12d315b7c6eb6
https://doi.org/10.1002/stem.1082
https://doi.org/10.1002/stem.1082