Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chih-Yi Gabriela Lin"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 11, p e1006403 (2016)
The maintenance of chromosome integrity is crucial for genetic stability. However, programmed chromosome fragmentations are known to occur in many organisms, and in the ciliate Tetrahymena the five germline chromosomes are fragmented into hundreds of
Externí odkaz:
https://doaj.org/article/b43d8965bbbe46b6b541f86357d23dca
Autor:
Alexandra Vancevska, Joachim Lingner, Chih-Yi Gabriela Lin, Anna Christina Naeger, Thomas Lunardi, Gérald Lossaint
Publikováno v:
Nucleic Acids Research
Telomere shortening can cause detrimental diseases and contribute to aging. It occurs due to the end replication problem in cells lacking telomerase. Furthermore, recent studies revealed that telomere shortening can be attributed to difficulties of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90c389a0b2fa0d68eeaf64c741939bb
https://doi.org/10.1093/nar/gkab1015
https://doi.org/10.1093/nar/gkab1015
Publikováno v:
Nucleic Acids Research
Eukaryotic cells pack their genomic DNA into euchromatin and heterochromatin. Boundaries between these domains have been shown to be set by boundary elements. In Tetrahymena, heterochromatin domains are targeted for deletion from the somatic nuclei t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfcef0ec647d9271a088d1ede9d4885
https://doi.org/10.1093/nar/gkz481
https://doi.org/10.1093/nar/gkz481
Autor:
Meng-Chao Yao, Chih-Yi Gabriela Lin, Chao-Yin Cheng, Ju-Lan Chao, Janet M. Young, Harmit S. Malik
Publikováno v:
Genesdevelopment. 30(24)
Ciliated protozoans perform extreme forms of programmed somatic DNA rearrangement during development. The model ciliate Tetrahymena thermophila removes 34% of its germline micronuclear genome from somatic macronuclei by excising thousands of internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64285d996c0d2f8603b708b5b1874d2a
https://pubmed.ncbi.nlm.nih.gov/28087716
https://pubmed.ncbi.nlm.nih.gov/28087716
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 11, p e1006403 (2016)
PLoS Genetics, Vol 12, Iss 11, p e1006403 (2016)
The maintenance of chromosome integrity is crucial for genetic stability. However, programmed chromosome fragmentations are known to occur in many organisms, and in the ciliate Tetrahymena the five germline chromosomes are fragmented into hundreds of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b71940cd0453cf66f7b274d1db31e3
https://doi.org/10.1371/journal.pgen.1006403
https://doi.org/10.1371/journal.pgen.1006403
Publikováno v:
Nucleic Acids Research; 7/26/2019, Vol. 47 Issue 13, p7143-7144, 2p, 1 Graph