Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chih-Wei Fan"'
Autor:
Jason E. Toombs, Steven Y. Cheng, John Tyler Piazza, Joseph T. Opferman, Lawrence G. Lum, Quinn Barrett, Loren D. Walensky, Xuewu Zhang, Douglas R. Green, Yi Chun Kuo, Tudor Moldoveanu, Rubina Tuladhar, Rolf A. Brekken, Chih Wei Fan, Li Shu Zhang, Xiaofeng Wu, Marcel Kool
Publikováno v:
Nature Cell Biology. 19:1226-1236
Direct interactions between pro- and anti-apoptotic BCL-2 family members form the basis of cell death decision-making at the outer mitochondrial membrane (OMM). Here we report that three anti-apoptotic BCL-2 proteins (MCL-1, BCL-2 and BCL-XL) found u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd3936e3e1cccd7c58db549b65e784a
https://doi.org/10.1038/ncb3616
https://doi.org/10.1038/ncb3616
Autor:
Shuguang Wei, Chuo Chen, Emilio Hirsch, Chih Wei Fan, Wei Tang, Baozhi Chen, Chang-Guang Wang, Lawrence G. Lum, Irene Franco, Noelle S. Williams, Jianming Lu, Michael G. Roth, Xiaofeng Wu, Heping Shi
Publikováno v:
Chemistry & Biology. 21:1680-1689
SummaryMisactivation of the seven-transmembrane protein Smoothened (Smo) is frequently associated with basal cell carcinoma and medulloblastoma. Cellular exposure to secreted Hedgehog (Hh) protein or oncogenic mutations in Hh pathway components induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9783bb89e22f649447548d0fe7dc1c
https://doi.org/10.1016/j.chembiol.2014.10.013
https://doi.org/10.1016/j.chembiol.2014.10.013
Publikováno v:
Advances in Intelligent Information Hiding and Multimedia Signal Processing ISBN: 9783319502113
A coplanar symmetric dipole slot antenna is proposed for dual band wireless communication applications. The rectangular slot with T tuning stub is etched on the metallic layer of a single sided printed circuit board to form the coplanar dipole slot a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0acca0ce2587fd98dfddceb409381c
https://doi.org/10.1007/978-3-319-50212-0_29
https://doi.org/10.1007/978-3-319-50212-0_29
Autor:
Lawrence G. Lum, Brett Lomenick, Lih Wen Deng, Qiaoling Wang, Chih Wei Fan, Shuanhu Gao, Jing Huang, Jie Liu, Gelin Wang, Chuo Chen
Publikováno v:
Synlett. 23:2298-2310
Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the chemistry and biology of this natural product.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c1c8318157021673c72c2ab463c3be
https://doi.org/10.1055/s-0031-1290460
https://doi.org/10.1055/s-0031-1290460
Autor:
Michael E. Dodge, Wayne Hao, Jessica A. Kilgore, Wei Tang, Baozhi Chen, Chuo Chen, Michael G. Roth, Lawrence G. Lum, James F. Amatruda, Jianming Lu, Zhiqiang Ma, Noelle S. Williams, Shuguang Wei, Chih Wei Fan
Publikováno v:
Nature chemical biology
The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses. By screening a diverse synthetic chemical library, we h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3f87240d10c50c2b2f570253bbed4f
https://doi.org/10.1038/nchembio.137
https://doi.org/10.1038/nchembio.137
Autor:
Chuo Chen, Jamie Longgood, Lawrence G. Lum, Chih Wei Fan, Zhiqiang Ma, James F. Amatruda, Noelle S. Williams, Jen-Chieh Hsieh, Baozhi Chen, Jianming Lu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:3825-3827
Suppression of oncogenic Wnt-mediated signaling holds promise as an anti-cancer therapeutic strategy. We previously reported a novel class of small molecules (IWR-1/2, inhibitors of Wnt response) that antagonize Wnt signaling by stabilizing the Axin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114caec7d4600d2de1c138d4f9d5ca9f
https://doi.org/10.1016/j.bmcl.2009.04.040
https://doi.org/10.1016/j.bmcl.2009.04.040
Autor:
Chih-Wei Fan, 范芝瑋
95
Xanthomonas campestris pv. campestris is a Gram-negative bacterium that relies on type II secretion system for secreting hydrolytic enzymes in their infection of plant leaves. The X. campestris type II secretion system is composed of 12 Xps p
Xanthomonas campestris pv. campestris is a Gram-negative bacterium that relies on type II secretion system for secreting hydrolytic enzymes in their infection of plant leaves. The X. campestris type II secretion system is composed of 12 Xps p
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/40498825524272720890
Autor:
Chih-Wei Fan-Chiang, 范姜智為
96
Routing in peer-to-peer networks or application-layer multicast can be regarded as the process of parent locating and selecting. Many algorithms in the literature adopt some monotonic criterion to choose parents. In this paper, we propose a n
Routing in peer-to-peer networks or application-layer multicast can be regarded as the process of parent locating and selecting. Many algorithms in the literature adopt some monotonic criterion to choose parents. In this paper, we propose a n
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/02521750752825131094
Publikováno v:
Nature Chemical Biology. 9:217-218
Secreted Hedgehog (Hh) proteins are essential in development, and their aberrant activity contributes to certain cancers. Chemically targeting a lipid modification of Hh proteins results in loss of their cellular activity, revealing new strategies fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633f4b20fa1561051337f2805aed1ff1
https://doi.org/10.1038/nchembio.1209
https://doi.org/10.1038/nchembio.1209
Autor:
Shuanhu Gao, Qiaoling Wang, Gelin Wang, Brett Lomenick, Jie Liu, Chih-Wei Fan, Lih-Wen Deng, Jing Huang, Lawrence Lum, Chuo Chen
Publikováno v:
Synlett; Oct2012, Vol. 23 Issue 16, p2298-2310, 13p