Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chih-Jen Lai"'
Autor:
Dokyun Kim, Eunha Kim, Semi Kim, Youseung Chung, Chih-Jen Lai, Inho Cha, Sung-Dong Cho, Yunseo Choi, Xinghong Dai, Stephanie Kim, Seokmin Kang, Mi-Jeong Kwak, Ziyi Liu, Younho Choi, Su-Hyung Park, Young Ki Choi, Jae U. Jung
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Dabie bandavirus (DBV), previously known as severe fever with thrombocytopenia syndrome (SFTS) virus, induces a characteristic thrombocytopenia with a mortality rate ranging from 12% to as high as 30%. The sero-prevalence of DBV in healthy p
Externí odkaz:
https://doaj.org/article/6081eecbaf4b4ea0952b801b20c85d73
Publikováno v:
Viruses, Vol 16, Iss 1, p 128 (2024)
SFTSV is an emerging tick-borne virus causing hemorrhagic fever with a case fatality rate (CFR) that can reach up to 27%. With endemic infection in East Asia and the recent spread of the vector tick to more than 20 states in the United States, the SF
Externí odkaz:
https://doaj.org/article/1934faf453d646d29ec87aedb8d63a38
Autor:
Jinyeop Song, Bo-Seong Jeong, Seong-Woo Kim, Seong-Bin Im, Seonghoon Kim, Chih-Jen Lai, Wonki Cho, Jae U Jung, Myung-Ju Ahn, Byung-Ha Oh
Publikováno v:
eLife, Vol 12 (2023)
Immunoglobulin G (IgG) antibodies are widely used for diagnosis and therapy. Given the unique dimeric structure of IgG, we hypothesized that, by genetically fusing a homodimeric protein (catenator) to the C-terminus of IgG, reversible catenation of a
Externí odkaz:
https://doaj.org/article/63898ee2d57b4962bbcf50134986f256
Autor:
Tian Xia, Xin Wu, Eunjin Hong, Kyle Jung, Chih-Jen Lai, Mi-Jeong Kwak, Hogyu Seo, Stephanie Kim, Zhongyi Jiang, Inho Cha, Jae U Jung
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011232 (2023)
Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV). As etiologic agents of hemorrhagic fever with high fatality, HRTV and DBV have been re
Externí odkaz:
https://doaj.org/article/5881408929ae41b6bb272edd69438342
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f4b7829f502246228e068391dd769f8d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
More than 80% of SARS-CoV-2 variants, including Alpha and Omicron, contain an N501Y mutation in the receptor-binding domain (RBD) of the spike protein. The N501Y change is an adaptive mutation enabling tighter interaction with the human ACE2 receptor
Externí odkaz:
https://doaj.org/article/bfc3c6c3b8b14652a2710c45c89cdd42
Autor:
Chang-Hsun Ho, Mei-Lin Chen, Hau-Lun Huang, Chih-Jen Lai, Chih-Hsin Liu, Chih-Pin Chuu, Yu-Hsin Lin
Publikováno v:
Marine Drugs, Vol 20, Iss 9, p 542 (2022)
The standard of care for prostate cancer (PCa) is androgen deprivation therapy (ADT). Although hormone-sensitive PCa is curable by ADT, most conditions progress to castration-resistant prostate cancer (CRPCa) and metastatic CRPCa (mCRPCa). Front-line
Externí odkaz:
https://doaj.org/article/bb95d9cf20d24da5a50da642f7b4c68d
Autor:
Young-Il Kim, Dokyun Kim, Kwang-Min Yu, Hogyu David Seo, Shin-Ae Lee, Mark Anthony B. Casel, Seung-Gyu Jang, Stephanie Kim, WooRam Jung, Chih-Jen Lai, Young Ki Choi, Jae U. Jung
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of the CoV disease 2019 (COVID-19) pandemic, enters host cells via the interaction of its receptor-binding domain (RBD) of the spike protein with host angiotensin-convert
Externí odkaz:
https://doaj.org/article/28c7b10f0f2446b1a7fdbe067aabdadd
Publikováno v:
Cells, Vol 8, Iss 4, p 295 (2019)
Patients receiving docetaxel developed a drug resistance within a few months. We generated docetaxel-resistant PC/DX25 and DU/DX50 CRPC cells from PC-3 and DU-145 PCa cells, respectively. We investigated the mechanism behind why PC/DX25 and DU/DX50 c
Externí odkaz:
https://doaj.org/article/74778620261241d0960f9f020d1d9a5a
Autor:
Chih-Jen Lai, 賴志仁
89
The current multicast routing protocols in Internet do not work well due to the frequent changes of mobile host location. To efficiently support multicast delivery mobile nodes, Mobile IP must include some additional mechanisms. Several proto
The current multicast routing protocols in Internet do not work well due to the frequent changes of mobile host location. To efficiently support multicast delivery mobile nodes, Mobile IP must include some additional mechanisms. Several proto
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/79165068327409311112