Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Chih-Chien Hsu"'
Autor:
Hsiao-Jung Kao, Ting-Yi Lin, Feng-Jen Hsieh, Jia-Ying Chien, Erh-Chan Yeh, Wan-Jia Lin, Yi-Hua Chen, Kai-Hsuan Ding, Yu Yang, Sheng-Chu Chi, Ping-Hsing Tsai, Chih-Chien Hsu, De-Kuang Hwang, Hsien-Yang Tsai, Mei-Ling Peng, Shi-Huang Lee, Siu-Fung Chau, Chen Yu Chen, Wai-Man Cheang, Shih-Jen Chen, Pui-Yan Kwok, Shih-Hwa Chiou, Mei-Yeh Jade Lu, Shun-Ping Huang
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-7 (2024)
Abstract Our study presents a 319-gene panel targeting inherited retinal dystrophy (IRD) genes. Through a multi-center retrospective cohort study, we validated the assay’s effectiveness and clinical utility and characterized the mutation spectrum o
Externí odkaz:
https://doaj.org/article/483be3c5b3ae4fb894f541f92bf270b0
Autor:
Shih-Yuan Peng, Chih-Ying Chen, Hsin Chen, Yi-Ping Yang, Mong-Lien Wang, Fu-Ting Tsai, Chian-Shiu Chien, Pei-Yu Weng, En-Tung Tsai, I-Chieh Wang, Chih-Chien Hsu, Tai-Chi Lin, De-Kuang Hwang, Shih-Jen Chen, Shih-Hwa Chiou, Chuan-Chin Chiao, Yueh Chien
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117270- (2024)
The blood supply in the retina ensures photoreceptor function and maintains regular vision. Leber's hereditary optic neuropathy (LHON), caused by the mitochondrial DNA mutations that deteriorate complex I activity, is characterized by progressive vis
Externí odkaz:
https://doaj.org/article/b4bc963805ae492b864a5363be659184
Autor:
Chien-Hung Shih, Hao-Kai Chuang, Tzu-Hung Hsiao, Yi-Ping Yang, Chong-En Gao, Shih-Hwa Chiou, Chih-Chien Hsu, De-Kuang Hwang
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Age-related macular degeneration (AMD) is the main cause of severe vision loss in elderly populations of the developed world with limited therapeutic medications available. It is a multifactorial disease with a strong genetic susceptibili
Externí odkaz:
https://doaj.org/article/37390bb85e3e45e6816c22f5d70b7d64
Autor:
Ting-Yi Lin, Hung-Ruei Chen, Hsin-Yi Huang, Yu-Ier Hsiao, Zih-Kai Kao, Kao-Jung Chang, Tai-Chi Lin, Chang-Hao Yang, Chung-Lan Kao, Po-Yin Chen, Shih-En Huang, Chih-Chien Hsu, Yu-Bai Chou, Ying-Chun Jheng, Shih-Jen Chen, Shih-Hwa Chiou, De-Kuang Hwang
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
PurposeDiabetic macular edema (DME) is one of the leading causes of visual impairment in diabetic retinopathy (DR). Physicians rely on optical coherence tomography (OCT) and baseline visual acuity (VA) to tailor therapeutic regimen. However, best-cor
Externí odkaz:
https://doaj.org/article/99964e589f264b8193c011a21286f9f5
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 11, Iss 2, Pp 175-178 (2021)
Pseudophakic bullous keratopathy and Fuchs' endothelial dystrophy are the two most common causes of corneal edema after cataract surgery. We report a 61-year-old alcoholic male with bilateral corneal edema that improved after his alcohol abstinence.
Externí odkaz:
https://doaj.org/article/4c4490f413d2440792afba5009ab62ca
Autor:
Chih-Chien Hsu, Ke-Hung Chien, Aliaksandr A. Yarmishyn, Waradee Buddhakosai, Wen-Ju Wu, Tai-Chi Lin, Shih-Hwa Chiou, Jiann-Torng Chen, Chi-Hsien Peng, De-Kuang Hwang, Shih-Jen Chen, Yuh-Lih Chang
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Transient receptor potential vanilloid 1 (TRPV1), recognized as a hyperosmolarity sensor, is a crucial ion channel involved in the pathogenesis of neural and glial signaling. Recently, TRPV1 was determined to play a role in retina
Externí odkaz:
https://doaj.org/article/fc0adb75034145b5bcab57c8d443304f
Autor:
Chih-Chien Hsu, Hao-Kai Chuang, Yu-Jer Hsiao, Yuan-Chi Teng, Pin-Hsuan Chiang, Yu-Jun Wang, Ting-Yi Lin, Ping-Hsing Tsai, Chang-Chi Weng, Tai-Chi Lin, De-Kuang Hwang, Ai-Ru Hsieh
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1920 (2022)
Cataracts, characterized by crystalline lens opacities in human eyes, is the leading cause of blindness globally. Due to its multifactorial complexity, the molecular mechanisms remain poorly understood. Larger cohorts of genome-wide association studi
Externí odkaz:
https://doaj.org/article/cb06ac1206924dadafd2c3fa8d73bd8a
Autor:
Kao-Jung Chang, Hsin-Yu Wu, Aliaksandr A. Yarmishyn, Cheng-Yi Li, Yu-Jer Hsiao, Yi-Chun Chi, Tzu-Chen Lo, He-Jhen Dai, Yi-Chiang Yang, Ding-Hao Liu, De-Kuang Hwang, Shih-Jen Chen, Chih-Chien Hsu, Chung-Lan Kao
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9707 (2022)
Cerebral visual impairments (CVIs) is an umbrella term that categorizes miscellaneous visual defects with parallel genetic brain disorders. While the manifestations of CVIs are diverse and ambiguous, molecular diagnostics stand out as a powerful appr
Externí odkaz:
https://doaj.org/article/a79c52104b5d47f1ac38c7fedf6ee6ee
Publikováno v:
BMC Ophthalmology, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background To evaluate the diagnostic ability of macular ganglion cell asymmetry to diagnose preperimetric glaucoma (PPG), using Cirrus spectral domain optical coherence tomography (OCT). Methods This prospective study included 67 eyes of 67
Externí odkaz:
https://doaj.org/article/1779533a39464f38b49f5ed6b9d61fa7
Autor:
Jen-Hua Chuang, Aliaksandr A. Yarmishyn, De-Kuang Hwang, Chih-Chien Hsu, Mong-Lien Wang, Yi-Ping Yang, Ke-Hung Chien, Shih-Hwa Chiou, Chi-Hsien Peng, Shih-Jen Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-17 (2018)
Abstract Background Differentiation of human induced pluripotent stem cells (hiPSCs) into retinal lineages offers great potential for medical application. Therefore, it is of crucial importance to know the key intrinsic regulators of differentiation
Externí odkaz:
https://doaj.org/article/13ab8070040c4645a0414d508afa554b