Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Chih-Chang Chu"'
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Triple negative breast cancer (TNBC) has the worst overall survival among all breast cancer subtypes; 80% of TNBC harbors TP53 mutation. Gambogic acid (GA) is an herbal compound isolated from the dry brownish gamboge resin of Garcinia hanburyi. A new
Externí odkaz:
https://doaj.org/article/9ea461cd2fa940b982a53c36ca364ea1
Autor:
Chih-Chang Chu, 朱志昌
94
There have been unceasing battles in the Middle East after the World War Ⅱ. Palestinian occupied by Israel is always the issue of political confrontation in the Middle East. The critical point of conflicts between Israel and Palestinian Ara
There have been unceasing battles in the Middle East after the World War Ⅱ. Palestinian occupied by Israel is always the issue of political confrontation in the Middle East. The critical point of conflicts between Israel and Palestinian Ara
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/99827736265378814262
Publikováno v:
Biomaterials Science.
By exploring the structural design and tunability of polymeric nanocarriers, amino acid-based poly(ester urea urethane) is developed as a delivery vehicle for gambogic acid in the treatment of triple negative breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b852374d8c2172fa65ac9e0c573a7b
https://doi.org/10.1039/d3bm00128h
https://doi.org/10.1039/d3bm00128h
Publikováno v:
ACS Applied Materials & Interfaces. 13:14688-14699
Developing a new family of hydrogel-based wound dressings that could have a dual biofunctionality of antibacterial and biological responses is highly desirable. In this study, an inherently effective antibacterial and biodegradable hydrogel dressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fbc39a6f4074e4c1786b0273a11749
https://doi.org/10.1021/acsami.0c21680
https://doi.org/10.1021/acsami.0c21680
Autor:
Chih-Chang Chu, Qinghua Xu
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:524-537
Reactive oxygen species (ROS) play an important role in cellular metabolism and many oxidative stress related diseases. Oxidative stress results from toxic effects of ROS and plays a critical role in the pathogenesis of a variety of diseases like can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b2fb871594618f776257d0d3c2eef2
https://doi.org/10.1002/jbm.a.37035
https://doi.org/10.1002/jbm.a.37035
Publikováno v:
Nanoscale. 11:9987-10003
Reduction-sensitive nanomedicine is a promising strategy to achieve controlled release of payloads in response to intracellular reductive milieu. However, endolysosomal sequestration of internalized carriers and insufficient redox potential in endoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ae4ee058cf507cfc0c14ead25aab4c
https://doi.org/10.1039/c9nr01909j
https://doi.org/10.1039/c9nr01909j
Publikováno v:
Journal of materials chemistry. B. 3(11)
A novel L-lysine based multifunctional crosslinker family was developed and utilized to fabricate a 100% pure poly(ester amide) (PEA) hydrogel with unique structure via a novel gelation strategy in a single and rapid step. Enzyme triggered biodegrada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175c64488d822ad9afc26e33d4cdaa88
https://pubmed.ncbi.nlm.nih.gov/32262058
https://pubmed.ncbi.nlm.nih.gov/32262058
Publikováno v:
Journal of materials chemistry. B. 2(38)
In this study, we reported the development of a new drug encapsulation strategy and a robust hybrid hydrogel platform for controlled and sustained release of small and large molecule ionic drugs. A biodegradable, biocompatible and temperature stimuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4eec55ff5079a9216ad664251972a4
https://pubmed.ncbi.nlm.nih.gov/32261826
https://pubmed.ncbi.nlm.nih.gov/32261826
Publikováno v:
Journal of materials chemistry. B. 6(13)
The generation of CD8 T cells is crucial in adaptive immunity against cancer and many infectious diseases. Vaccines aimed to stimulate CD8 T cell response typically become ineffective because the antigens are subject to sequestration in endocytic com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b287597788ea5ded9a998199d457ed
https://pubmed.ncbi.nlm.nih.gov/32254359
https://pubmed.ncbi.nlm.nih.gov/32254359
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 159:78-88
Selected from the family of self-designed biodegradable amino acid-based poly (ester urea urethane) (AA-PEUU) pseudo-protein biomaterials, arginine-leucine based poly (ester urea urethane)s (Arg-Leu-PEUUs) were used as protective and bio-functional c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468f646c2cccc8cec71a0d9f24529b0e
https://doi.org/10.1016/j.colsurfb.2017.07.031
https://doi.org/10.1016/j.colsurfb.2017.07.031