Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chih Jou Su"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Nitrogen permease regulator-like 2 (NPRL2/TUSC4) is known to exert both tumor-suppressing and oncogenic effects in different types of cancers, suggesting that its actions are context dependent. Here, we delineated the molecular and functiona
Externí odkaz:
https://doaj.org/article/ff5d7e7199d949a8aa0332b54ea9d28f
Autor:
Huang-Ju Tu1, Chih-Jou Su2, Chao-Shiang Peng2, Tony Eight Lin1,3, Wei-Chun HuangFu1,2,3,4,5, Kai-Cheng Hsu1,2,3,4,5, Tsong-Long Hwang6,7,8,9 htl@mail.cgu.edu.tw, Shiow-Lin Pan1,2,3,4,5,10 slpan@tmu.edu.tw
Publikováno v:
Journal of Food & Drug Analysis. 2023, Vol. 31 Issue 2, p358-370. 13p.
Autor:
Kunal Nepali, Wei Chun HuangFu, Shiow Lin Pan, Mei Jung Lai, Ritu Ojha, Yi Wen Wu, Han Li Huang, Jing Ping Liou, Chih Jou Su, Ting Yi Sung, Yi Lin Chen
Publikováno v:
European Journal of Medicinal Chemistry. 150:667-677
A series of 1-aroylindoline-hydroxamic acids have been synthesized in the present study. The results of the biological evaluation led to the identification of compound 12 as dual HDAC6/HSP90 inhibitor. Compound 12 displayed striking inhibitory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff692ca4907113cd97d023bc2d3148c
https://doi.org/10.1016/j.ejmech.2018.03.006
https://doi.org/10.1016/j.ejmech.2018.03.006
Publikováno v:
Journal of Clinical Medicine
Volume 8
Issue 5
Journal of Clinical Medicine, Vol 8, Iss 5, p 659 (2019)
Volume 8
Issue 5
Journal of Clinical Medicine, Vol 8, Iss 5, p 659 (2019)
The chemokines CXCL9 and CCL20 have been reported to be associated with ventricular dysfunction. This study was aimed to investigate the effects of CXCL9/CCL20 on cardiac fibrosis following myocardial infarction (MI). Blood samples of patients with M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180e957d6f8f4dd4fd7b0f087603121c
Autor:
Hsueh Yun Lee, Ting Yi Sung, Jing Ping Liou, Chia-Ron Yang, Sunil Kumar, Chih Jou Su, Chih Yi Chang, Yuh Hsuan Chao, Chia Ming Hsu, Yi Zhen Huang, Samir Mehndiratta, Yu Hsuan Li, Han Li Huang
Publikováno v:
European Journal of Medicinal Chemistry. 122:92-101
This study reports the design and synthesis of 2-(phenylsulfonyl)quinoline N-hydroxyacrylamides (8a–k). Structure-activity relationship studies focusing on regio-effect of N-hydroxyacrylamide moiety and influence of the sulfonyl linker revealed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7774d43412cedf48b3193d8e6c4183e4
https://doi.org/10.1016/j.ejmech.2016.06.023
https://doi.org/10.1016/j.ejmech.2016.06.023
Autor:
Chih Jou Su, Wei Jan Huang, Liang Chieh Chen, Chen Yu Wang, Ying Chen Yang, Hui Ju Tseng, Young Ji Shiao, Shiow Lin Pan, Mei Hsiang Lin, Jung Chun Chu, Kai Cheng Hsu, Tony Eight Lin, Yi Ying Chen, Chun Yung Chen
Publikováno v:
European Journal of Medicinal Chemistry. 192:112193
Multitarget agents simultaneously trigger molecules in functionally complementary pathways, and are therefore considered to have potential in effectively treating Alzheimer's disease (AD), which has a complex pathogenetic mechanism. In this study, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9191d0a3a53a56e3d3ee4fe8d3ef9277
https://doi.org/10.1016/j.ejmech.2020.112193
https://doi.org/10.1016/j.ejmech.2020.112193
Autor:
Chih Jou Su, Samir Mehndiratta, Yi Wen Wu, Han Li Huang, Shiow Lin Pan, Chia Ming Hsu, Ruei Shian Wang, Jing Ping Liou
Publikováno v:
European journal of medicinal chemistry. 134
A series of 4,5-indolyl-N-hydroxyphenylacrylamides, as HDAC inhibitors, has been synthesized and evaluated in vitro and in vivo. 4-Indolyl compounds 13 and 17 functions as potent inhibitors of HDAC1 (IC50 1.28 nM and 1.34 nM) and HDAC 2 (IC50 0.90 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec8ef8cf4491e5d8b0e539d0956e3c2
https://pubmed.ncbi.nlm.nih.gov/28395150
https://pubmed.ncbi.nlm.nih.gov/28395150
Autor:
Chih-Jou Su, 蘇致柔
102
Heat shock transcription factor-1 (HSF1) is a master regulator of heat shock response, which not only restores the normal protein folding environment but modulates cellular signaling pathways and metabolism to maintain cell survival under st
Heat shock transcription factor-1 (HSF1) is a master regulator of heat shock response, which not only restores the normal protein folding environment but modulates cellular signaling pathways and metabolism to maintain cell survival under st
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/5c9h9q
