Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Chih Hsiung Lai"'
Autor:
Abram Bunya Kamiza, Wen-Chang Wang, Jeng-Fu You, Reiping Tang, Huei-Tzu Chien, Chih-Hsiung Lai, Li-Ling Chiu, Tsai-Ping Lo, Kuan-Yi Hung, Chao A. Hsiung, Chih-Ching Yeh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Patients with Lynch syndrome have a high risk of colorectal cancer (CRC). In this study, we estimated the age- and sex-specific cumulative risks of CRC in Han Chinese patients with Lynch syndrome caused by the pathogenic germline mutations i
Externí odkaz:
https://doaj.org/article/4d5c960d35bb4e03a866c9c43b2d7bfd
Autor:
Shiang-Fu Huang, Huei-Tzu Chien, Wen-Yu Chuang, Chih-Hsiung Lai, Sou-De Cheng, Chun-Ta Liao, Hung-Ming Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract This study was designed to explore the relationship between epidermal growth factor receptor (EGFR) CA repeats polymorphism and protein expression in oral cavity squamous cell carcinoma (OSCC). A total of 194 OSCCs were examined for EGFR pro
Externí odkaz:
https://doaj.org/article/b760cba4ad5c42d0a1f836131337a9ec
Autor:
Abram Bunya Kamiza, Ling-Ling Hsieh, Reiping Tang, Huei-Tzu Chien, Chih-Hsiung Lai, Li-Ling Chiu, Tsai-Ping Lo, Kuan-Yi Hung, Jeng-Fu You, Wen-Chang Wang, Chao A Hsiung, Chih-Ching Yeh
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167354 (2016)
TP53 encodes p53, which has a crucial role in modulating genes that regulate defense against cancer development. This study investigated whether TP53 polymorphisms are associated with colorectal cancer (CRC) in patients with Lynch syndrome and whethe
Externí odkaz:
https://doaj.org/article/fd1bfe36c0c2437ba8fd09bf735fa224
Autor:
Abram Bunya Kamiza, Ling-Ling Hsieh, Reiping Tang, Huei-Tzu Chien, Chih-Hsiung Lai, Li-Ling Chiu, Tsai-Ping Lo, Kuan-Yi Hung, Chun-Yi Wang, Jeng-Fu You, Chao A Hsiung, Chih-Ching Yeh
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130018 (2015)
Background and aimLynch syndrome, caused by germline mutations in mismatch repair genes, is a predisposing factor for colorectal cancer (CRC). This retrospective cohort study investigated the risk factors associated with the development of CRC in pat
Externí odkaz:
https://doaj.org/article/62ad19c390f84d72a86be23d76eb7dd9
Autor:
Wen Chang Wang, Kuan Yi Hung, Reiping Tang, Chih Ching Yeh, Chao A. Hsiung, Chih Hsiung Lai, Huei Tzu Chien, Li Ling Chiu, Jeng Fu You, Tsai Ping Lo, Abram Bunya Kamiza
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Patients with Lynch syndrome have a high risk of colorectal cancer (CRC). In this study, we estimated the age- and sex-specific cumulative risks of CRC in Han Chinese patients with Lynch syndrome caused by the pathogenic germline mutations in MLH1 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b03958ca5c22dfaac7ba04235287e06
http://europepmc.org/articles/PMC8076276
http://europepmc.org/articles/PMC8076276
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65578 (2013)
Somatic mutations affecting the mitochondrial DNA (mtDNA) have been frequently observed in human cancers and proposed as important oncological biomarkers. However, the clinical significance of mtDNA mutations in cancer remains unclear. This study was
Externí odkaz:
https://doaj.org/article/b222295a734148139f8a8d6057861c16
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49684 (2012)
Reprogramming of energy metabolism in cancer cells has been directly/indirectly linked to mitochondria and mitochondrial functional defects and these changes seem to contribute to the development and progression of cancer. Studies have indicated that
Externí odkaz:
https://doaj.org/article/b99180da913549e58b8ad817db22063d
Autor:
Chih Hsiung Lai, Huei Tzu Chien, Abram Bunya Kamiza, Tsai Ping Lo, Li Ling Chiu, Jeng Fu You, Yen Ting Wang, Chao A. Hsiung, Kuan Yi Hung, Reiping Tang, Wen Chang Wang, Chih Ching Yeh
Publikováno v:
Anticancer Research. 38:5983-5990
BACKGROUND/AIM Epidermal growth factor receptor (EGFR), mothers against decapentaplegic homolog 7 (SMAD7) and transforming growth factor betta (TGFB) are crucial for colorectal cancer (CRC) tumorigenesis. This study investigated whether polymorphisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d070d9640ec657ecc1882ffb8b67929c
https://doi.org/10.21873/anticanres.12946
https://doi.org/10.21873/anticanres.12946
Autor:
Wen Chang Wang, Kuan Yi Hung, Reiping Tang, Chao A. Hsiung, Chih Hsiung Lai, Ling-Ling Hsieh, Chih Ching Yeh, Tsai Ping Lo, Jeng Fu You, Huei Tzu Chien, Abram Bunya Kamiza, Li Ling Chiu
Publikováno v:
Molecular Genetics & Genomic Medicine
Background DNA repair genes are crucial for maintaining genomic stability by preventing mutagenesis and carcinogenesis. The present retrospective cohort study aimed at investigating whether MLH1, APEX1, MUTYH, OGG1, NUDT1, XRCC5, XPA, and ERCC2 singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fce5b221aaa31a8573e16d76a64b54
https://doi.org/10.1002/mgg3.402
https://doi.org/10.1002/mgg3.402
Autor:
Huei Tzu Chien, Abram Bunya Kamiza, Li Ling Chiu, Kuan Yi Hung, Reiping Tang, Wen Chang Wang, Chun Yu Chang, Chao A. Hsiung, Jeng Fu You, Chih Hsiung Lai, Chih Ching Yeh, Tsai Ping Lo
Publikováno v:
Environmental and Molecular Mutagenesis. 59:69-78
Cytochrome P450 (CYP), glutathione-S-transferase (GST), and N-acetyltransferase (NAT) are crucial for metabolism and clearance of xenobiotics. This study investigated whether CYP, GST, and NAT single nucleotide polymorphisms (SNPs) are associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72015efef21e929e1fda525e454cb6d7
https://doi.org/10.1002/em.22113
https://doi.org/10.1002/em.22113