Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Chih Hang Anthony Tang"'
Autor:
Jianhuang Lin, Heng Liu, Takeshi Fukumoto, Joseph Zundell, Qingqing Yan, Chih-Hang Anthony Tang, Shuai Wu, Wei Zhou, Dajiang Guo, Sergey Karakashev, Chih-Chi Andrew Hu, Kavitha Sarma, Andrew V. Kossenkov, Rugang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The unfolded protein response (UPR) promotes cell survival in cancers with hyperactive ER stress response. Here the authors show that CARM1, an arginine methyltransferase, controls the IRE1α/XBP1 pathway of the UPR and the inhibition of this pathway
Externí odkaz:
https://doaj.org/article/30c7f569e8f14f29b50078b914b06fde
Autor:
Hee-Jin Choi, Chih-Hang Anthony Tang, Linlu Tian, Yongxia Wu, M. Hanief Sofi, Taylor Ticer, Steven D. Schutt, Chih-Chi Andrew Hu, Xue-Zhong Yu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective therapeutic procedure to treat hematological malignancies. However, the benefit of allo-HCT is limited by a major complication, chronic graft-versus-host disease (cGVHD). Since
Externí odkaz:
https://doaj.org/article/9e25414f671a4d1bbdb60cba5fd2b907
Autor:
Ethan A. Burns, Cesar Gentille Sanchez, Sunil Mathur, Carlo Guerrero, Ibrahim N. Muhsen, Humaira Sarfraz, Chih-Chi Andrew Hu, Chih-Hang Anthony Tang, Shilpan S. Shah, Ivo W. Tremont, Bin Teh, Siddhartha Ganguly, Sai Ravi Kiran Pingali
Publikováno v:
Annals of Hematology. 102:1111-1120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::768302d853775dcbfe2b3b0baa384869
https://doi.org/10.1007/s00277-023-05140-6
https://doi.org/10.1007/s00277-023-05140-6
Autor:
Steven D. Schutt, Yongxia Wu, Chih-Hang Anthony Tang, David Bastian, Hung Nguyen, M. Hanief Sofi, MengMeng Zhang, Chen Liu, Kris Helke, Carole Wilson, Lynn M. Schnapp, Juan R. Del Valle, Chih-Chi Andrew Hu, Xue-Zhong Yu
Publikováno v:
Blood Advances, Vol 2, Iss 4, Pp 414-427 (2018)
Abstract: Hematopoietic stem cell transplantation (HCT) is a curative procedure for hematological malignancies, but chronic graft-versus-host disease (cGVHD) remains a major complication after allogeneic HCT. Because donor B cells are essential for c
Externí odkaz:
https://doaj.org/article/62b4299a706f4f2383cc5657458d8883
Autor:
Brian C. Betts, Frederick L. Locke, Elizabeth M. Sagatys, Joseph Pidala, Kelly Walton, Meghan Menges, Jordan Reff, Asim Saha, Julie Y. Djeu, John V. Kiluk, Marie C. Lee, Jongphil Kim, Chang Won Kang, Chih-Hang Anthony Tang, Jeremy Frieling, Conor C. Lynch, Alan List, Paulo C. Rodriguez, Bruce R. Blazar, Jose R. Conejo-Garcia, Juan R. Del Valle, Chih-Chi Andrew Hu, Claudio Anasetti
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Acute graft- vs. -host disease (GVHD) is an important cause of morbidity and death after allogeneic hematopoietic cell transplantation (HCT). We identify a new approach to prevent GVHD that impairs monocyte-derived dendritic cell (moDC) alloactivatio
Externí odkaz:
https://doaj.org/article/d7d53dab35a0449b90de1bf45bb8064e
Autor:
Chih-Chi Andrew Hu, Dmitry I. Gabrilovich, Juan R. Del Valle, Anthony R. Mato, Chang Won Kang, Yi-Ju Chen, Ayumi Hashimoto, Shiun Chang, Chih-Hang Anthony Tang
Chronic lymphocytic leukemia (CLL) cells can secrete immunoglobulin M. However, it is not clear whether secretory IgM (sIgM) plays a role in disease progression. We crossed the Eμ-TCL1 mouse model of CLL, in which the expression of human TCL1 oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148821188c13909d5999a9abb024801d
https://doi.org/10.1158/2326-6066.c.6548944.v1
https://doi.org/10.1158/2326-6066.c.6548944.v1
Autor:
Chih-Chi Andrew Hu, Dmitry I. Gabrilovich, Juan R. Del Valle, Anthony R. Mato, Chang Won Kang, Yi-Ju Chen, Ayumi Hashimoto, Shiun Chang, Chih-Hang Anthony Tang
S1. Crosslinking and preparation of oligomeric HEL. S2. Oligomeric HEL crosslinks the BCR, and induces robust BCR signal transduction in MD4+/-/Eμ-TCL1+/+ B cells. S3. Oligomeric HEL activates a more rapid BCR signaling than F(ab')2 in MD4+/- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5997dccab85d957c2c21289e067017b2
https://doi.org/10.1158/2326-6066.22538920.v1
https://doi.org/10.1158/2326-6066.22538920.v1
Autor:
Chih-Chi Andrew Hu, Juan R. Del Valle, Chih-Hang Anthony Tang, Chang Won Kang, Christopher F. Cain, Walker T. Spalek, Qin Xu, Andong Shao
Supplementary methods, table, figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b9e6f1eaa41b7e186870e3934a1dc9
https://doi.org/10.1158/1535-7163.22518535
https://doi.org/10.1158/1535-7163.22518535
Autor:
Chih-Chi Andrew Hu, Juan R. Del Valle, Yulia Nefedova, Cindy Lin, Sujeewa Ranatunga, Joseph A. Zundell, Chih-Hang Anthony Tang
STING co-immunoprecipitates with IRE-1 (S1); Chemical structures of STING agonists (S2); Analysis of 3'3'-cGAMP by RP-HPLC and NMR (S3); STING does not undergo N-linked glycosylation before and after stimulations by 3'3'-cGAMP (S4); Deletion of mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad96f9399128e8ad1e4ad09b8011f105
https://doi.org/10.1158/0008-5472.22411131
https://doi.org/10.1158/0008-5472.22411131
Autor:
Chih-Chi Andrew Hu, Juan R. Del Valle, Yulia Nefedova, Cindy Lin, Sujeewa Ranatunga, Joseph A. Zundell, Chih-Hang Anthony Tang
Endoplasmic reticulum (ER) stress responses through the IRE-1/XBP-1 pathway are required for the function of STING (TMEM173), an ER-resident transmembrane protein critical for cytoplasmic DNA sensing, IFN production, and cancer control. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e11d2cf8ad31c3df0d9d08f0231683
https://doi.org/10.1158/0008-5472.c.6508164
https://doi.org/10.1158/0008-5472.c.6508164