Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chih Chan Lee"'
Autor:
Chih-Chan Lee, Jiunn-Chang Lin, Wei-Lun Hwang, Ying-Ju Kuo, Hung-Kai Chen, Shyh-Kuan Tai, Chun-Chi Lin, Muh-Hwa Yang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Tumor microenvironment varies between primary and metastatic sites. Here they report tumor-associated macrophages from metastatic sites to be predominantly M2 type, and secrete IL-35 to promote metastasis through activation of JAK2–STAT6–GATA3 si
Externí odkaz:
https://doaj.org/article/cec4741886e6453981505003b003d69a
Autor:
Chun-Chung Wang, Wan-Fen Li, Chih-Chan Lee, Lu-Tzu Chen, Jhih-Jie Yang, Jiann-Shiun Lai, Ming-Tain Lai
Publikováno v:
Cancer Research. 82:6111-6111
Immunogenic cell death (ICD) involves the activation of cytotoxic T lymphocyte-driven adaptive immunity with long-term immunological memory. OBI-3424 is a highly selective prodrug that is activated by AKR1C3 to release a potent bis-alkylating agent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ea7dff16d7ed1a0ee369de91c95967
https://doi.org/10.1158/1538-7445.am2022-6111
https://doi.org/10.1158/1538-7445.am2022-6111
Autor:
Chih Yung Yang, Yin Quan Chen, Jeng Kai Jiang, Chun Chi Lin, Chih Chan Lee, Hsin Yi Lan, Wei-Chung Cheng, Ruey Hwa Lu, Tzu Yu Yeh, Tsai Tsen Liao, Arthur Er Terg Chiou, Hung Hsin Lin, Shu Han Su, Wei Lun Hwang
Publikováno v:
Cancers, Vol 13, Iss 1833, p 1833 (2021)
Cancers
Volume 13
Issue 8
Cancers
Volume 13
Issue 8
Simple Summary Metastasis of tumor cells is the leading cause of death in cancer patients. Concurrent therapy with surgical removal of primary and metastatic lesions is the main approach for cancer therapy. Currently, therapeutic resistant properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b148b90f440643790cf07b827e66b5
https://doi.org/10.3390/cancers13081833
https://doi.org/10.3390/cancers13081833
Autor:
Chih-Chan Lee, 李志展
106
Epithelial plasticity of cancer cells, i.e., the dynamic change between epithelial and mesenchymal phenotypes of cancer cells, is thought to be critically involved in multiple steps of metastasis. The intriguing interplay between cancer cell
Epithelial plasticity of cancer cells, i.e., the dynamic change between epithelial and mesenchymal phenotypes of cancer cells, is thought to be critically involved in multiple steps of metastasis. The intriguing interplay between cancer cell
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/9rgwy4
Autor:
Wei Lun Hwang, Muh Hwa Yang, Chun Chi Lin, Hung Kai Chen, Chih Chan Lee, Ying Ju Kuo, Shyh Kuan Tai, Jiunn Chang Lin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
A favorable interplay between cancer cells and the tumor microenvironment (TME) facilitates the outgrowth of metastatic tumors. Because of the distinct initiating processes between primary and metastatic tumors, we investigate the differences in tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2252db06fab2779e7e7c86c3bddb3468
https://pubmed.ncbi.nlm.nih.gov/30218063
https://pubmed.ncbi.nlm.nih.gov/30218063
Autor:
Chien Tsun Chen, Yu-Ting Chou, Yau-Huei Wei, Sheng Chieh Lin, Chih Chan Lee, Cheng-Wen Wu, Chih Hung Chung, Chi Hsiu Chung, Yu Rong Kao, Sey En Lin, Yuan Hung Wang, Shih Hsin Hsiao
Publikováno v:
Stem Cells. 31:2607-2619
Tumor cells have long been observed to share several biological characteristics with normal stem/progenitor cells; however, the oncogenic mechanisms underlying the lung stem/progenitor cell signaling remain elusive. Here, we report that SOX2, a self-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e25010360ff288bf490d5a60dc4eb8b
https://doi.org/10.1002/stem.1518
https://doi.org/10.1002/stem.1518
Autor:
Chih-Chan Lee, 李志展
98
Aberrant expression and function of epidermal growth factor receptor (EGFR) is reported in most lung cancer cases. Sox2, a core transcription factor regulating self-renewal of stem cells, is highly expressed in lung cancer. We discovered that
Aberrant expression and function of epidermal growth factor receptor (EGFR) is reported in most lung cancer cases. Sox2, a core transcription factor regulating self-renewal of stem cells, is highly expressed in lung cancer. We discovered that
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/91356858696672476371
Autor:
Muh Hwa Yang, Chih-Chan Lee
Publikováno v:
Cancer Research. 75:474-474
Epithelial plasticity of cancer cells is considered to be critical for the metastatic process of cancer cells. Epithelial-mesenchymal transition (EMT) has been proved to associate with cancer metastatic dissemination from primary tumor site to distal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5773818ad057b12349416e24a9b2b99d
https://doi.org/10.1158/1538-7445.am2015-474
https://doi.org/10.1158/1538-7445.am2015-474
Autor:
Yu-Ting Chou, Cheng-Wen Wu, Sheng-Chieh Lin, Chih-Chan Lee, Yuan-Hung Wang, Sey-En Lin, Shih-Hsin Hsiao
Publikováno v:
Cancer Research. 73:5253-5253
Tumor cells have long been observed to share several biological characteristics with normal stem/progenitor cells; however, the oncogenic mechanisms underlying the stemness features remain elusive. Here we report the involvement of BCL2L1 in SOX2-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3d2d92b3a81ea6dd9185c71a3919326
https://doi.org/10.1158/1538-7445.am2013-5253
https://doi.org/10.1158/1538-7445.am2013-5253
Publikováno v:
Cancer Research. 71:4992-4992
Sox2, a core transcription factor regulating self-renewal of stem cells, is highly expressed in a subset of lung cancer. Nonetheless, how Sox2 contributes to lung tumorigenesis is still elusive. In this study, we report the discovery and mechanistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b9ea383ba15c1a250179e58f50f909
https://doi.org/10.1158/1538-7445.am2011-4992
https://doi.org/10.1158/1538-7445.am2011-4992