Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Chih‐Shone Lee"'
1
Metal Salt Mediated Radical Reactions of 2-Substituted-1,4-Naphthoquinones
Autor: Zhen Yu Lin, Chih Shone Lee, Che‐Ping Chuang, Yu Ling Chen
Publikováno v: European Journal of Organic Chemistry. 2010:3876-3882
The silver(II)- and manganese(III)-mediated radical reactions of 2-substituted-1,4-naphthoquinones are described. Acyl radicals generated by the oxidative decarboxylation of α-keto acids with silver(I) nitrate and persulfate undergo efficient radica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::759a4276014092c0a75f4d1cefc3e3a4
https://doi.org/10.1002/ejoc.201000272
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2
Radical-initiated cyclization as a key step for the synthesis of oxoprotoberberine alkaloids
Autor: Yen Yao Cheng, Tsung Ching Yu, Jian Wen Luo, Che‐Ping Chuang, Chih Shone Lee
Publikováno v: Tetrahedron Letters. 50:4558-4562
The oxoprotoberberine alkaloids 1a–d have been synthesized efficiently from the enamide derivatives 2a–d by a radical-initiated cyclization reaction utilizing n-Bu3SnH/AIBN and CuCl. The enamide derivatives 2a–d were prepared from phenylethylam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::045a42ac0dc7d1208990a54b22602c2f
https://doi.org/10.1016/j.tetlet.2009.05.095
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3
One-pot reductive-cyclization as key step for the synthesis of rutaecarpine alkaloids
Autor: Yuen-Lin Chiang, Cheng-Kuo Liu, Yen-Yao Cheng, Chih-Shone Lee
Publikováno v: Tetrahedron Letters. 49:481-484
The quinazolinocarboline alkaloids including rutaecarpine (1a), euxylophoricine A (1b), and euxylophoricine C (1c) have been synthesized efficiently from the ring opened β-carboline derivative as key intermediate by a one-pot reductive-cyclization r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8396d3647d694ebc409ae33101844512
https://doi.org/10.1016/j.tetlet.2007.11.094
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4
Free Radical Cyclizations in Alkaloid Total Synthesis: (±)-21-Oxogelsemine and (±)-Gelsemine
Autor: Shung C. Wu, David J. Hart, Joong-Kwon Choi, Subban Ramesh, Chih Shone Lee, Deok Chan Ha, Shogo Atarashi, Daniel Kuzmich
Publikováno v: Journal of the American Chemical Society. 119:6226-6241
Total syntheses of (±)-21-oxogelsemine (3) and (±)-gelsemine (1) are described. Free radical cyclizations play important roles in constructing the tricyclic core (40 → 41) and oxindole (93 → 96) substructures of the target alkaloids, and an iso
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dd5bf42840bb54f7de0b8f7e0655b78
https://doi.org/10.1021/ja970089h
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5
Mechanical and electrophysiological effects of 8-oxoberberine (JKL1073A) on atrial tissue
Autor: Chih-Shone Lee, Shu-Hsun Chu, Jo-Feng Chi, Nai-Kaun Chou, Ming-Jai Su
Publikováno v: British Journal of Pharmacology. 118:503-512
The effects of 8-oxoberberine (JKL1073A) on contractions and electrophysiological characteristics of atrial tissues were examined. In driven left atria of the rat JKL1073A (10-100 microM) increased twitch tension dose-dependently. In spontaneously be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7218710ce5e43a13d798d9c62604610
https://doi.org/10.1111/j.1476-5381.1996.tb15431.x
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6
Mode of inhibition of transient outward current by 1-benzyl-1,2,3,4-tetrahydroisoquinoline in rat ventricular cells
Autor: Ming-Jai Su, Chih-Shone Lee, Li Chen
Publikováno v: Journal of Biomedical Science. 3:211-220
In this study, we examined the effects of 1-benzyl-1,2,3,4-tetrahydroisoquinoline (S49) on a transient outward current (I(to)) in rat ventricular myocytes using the whole-cell patch-clamp technique. Depolarization of ventricular myocytes not only act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1cf41e8f7f51375425fab20be8816b
https://doi.org/10.1007/bf02253102
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8
Determination of Enantiomeric Purity and Absolute Configuration of β-Lactams by High-Performance Liquid Chromatography on Chiral Columns
Autor: Chih-Shone Lee, Hsiu-Ho Chen
Publikováno v: Journal of the Chinese Chemical Society. 41:187-190
Enantiomers of β-lactams bearing aryl, furyl or styryl substituents in the 4-position were chromatographically separated by means of high-performance liquid chromatography on chiral column packed with amino acid-derived chiral stationary phase. Sepa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5bd09050abea980799f79c99895a3565
https://doi.org/10.1002/jccs.199400026
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10
Enantioselective Synthesis of β-Lactam Carried C(3) Functionality via Ester Enolate-Imine Condensation
Autor: Hsiu-Ho Chen, Chih-Shone Lee
Publikováno v: Journal of the Chinese Chemical Society. 40:169-174
Enantioselective synthesis of optically active β-lactam via ester enolate-imine condensation using homochiral ester 16 and imine 17 provided β-lactam 18a in 77% cc. Lactam 18a, carried C(3) functionality on β-lactam nuclei, provided a potential pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acd4ef999f1cdb2f500d248b0f4f96e5
https://doi.org/10.1002/jccs.199300024
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