Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice

Autor: Chisayo Kozuka, Chigusa Shimizu-Okabe, Chitoshi Takayama, Kaku Nakano, Hidetaka Morinaga, Ayano Kinjo, Kotaro Fukuda, Asuka Kamei, Akihito Yasuoka, Takashi Kondo, Keiko Abe, Kensuke Egashira, Hiroaki Masuzaki

Publikováno v: Drug Delivery, Vol 24, Iss 1, Pp 558-568 (2017)

Our previous works demonstrated that brown rice-specific bioactive substance, γ-oryzanol acts as a chaperone, attenuates exaggerated endoplasmic reticulum (ER) stress in brain hypothalamus and pancreatic islets, thereby ameliorating metabolic derang

Externí odkaz: https://doaj.org/article/8b4813d137704330bf54da9b7008609d

Specific Expression of KCC2 in the α Cells of Normal and Type 1 Diabetes Model Mouse Pancreatic Islets

Autor: Chigusa Shimizu-Okabe, Shigeki Okada, Shiki Okamoto, Hiroaki Masuzaki, Chitoshi Takayama

Publikováno v: Acta histochemica et cytochemica. 55(1)

Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the mature brain; however, it acts excitatory during development. This difference in action depends on the intracellular chloride ion concentration, primarily regulated by potassium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd81a4f5efb7f272d17019d765d79b64
https://pubmed.ncbi.nlm.nih.gov/35444351

Contributors

Autor: Mareike Albert, C. Álvarez-Zaragoza, Brenda Angulo, Pauline Maciel August, Eva Ausó, André Rocha Barbosa, Renata Bartesaghi, Soledad Bárez-López, Dafna Ben Bashat, Liat Ben-Sira, Johanna Bendas, Christine Bibby, John W. Bigbee, Byron K.Y. Bitanihirwe, James A. Bourne, Antoine Bouyeure, Helena Brentani, J. Peter H. Burbach, Joshua A. Burk, F.J. Calabro, Victor Hugo Calegari de Toledo, Rita M. Cantor, Brian Chiou, Clodagh Cogley, Ilona Croy, Jorge Davila, Cheryl L. Dickter, Silvia Diviccaro, Stephanie D’Souza, Jeroen Dudink, Claire Enea-Drapeau, Carmen Espinós, Sade J. Faneyte, Arthur Sant’Anna Feltrin, Hilde Feys, Gianluca Gallo, A.A. García-Contreras, Laura Gaspari, Silvia Giatti, Courtney Gilchrist, Juan Antonio González-Barrios, Marisel González-Maya, Mihaela Grigore, Ana-Maria Grigore, Carmen Grijota-Martínez, Carlos M. Gómez, Ana Guadaño-Ferraz, Sandra Guidi, Loredana-Maria Himiniuc, Freek E. Hoebeek, Janine Hoffmann, Kurt L. Hoffman, Jihane Homman-Ludiye, Kiho Im, Iris Žunić Išasegi, Keiichi Ishihara, Ismael Jiménez-Estrada, Vijaya Kancherla, Tomohisa Katada, Ana Katušić, Sahar Kiani, Jeongtae Kim, Gregory W. Kirschen, Masaaki Kitada, Caroline Peres Klein, Katrijn Klingels, Shiori Kobayashi, Yoshinori Kosaka, Ivica Kostović, Mirna Kostović Srzentić, Željka Krsnik, Jennifer K. Lowe, Daniela López-Espíndola, B. Luna, Vincenzo Lupo, Zilu Ma, Lisa Mailleux, Louis N. Manganas, Vladimir Martínez-Álvarez, Mariana Maschietto, Cristiane Matté, Nadia McMillan, Roberto Cosimo Melcangi, Angel I. Melo, Elka Miller, Sara Mirsadeghi, A.J. Mitchell, Edwin A. Mitchell, Esraa Mohamed, Ruth Monaghan, Ana Montero-Pedrazuela, C.W. Musket, Marion Noulhiane, Tadahiro Numakawa, Haruki Odaka, Akihito Okabe, Fiadhnait O’Keeffe, Els Ortibus, Xianhua Piao, Hector Ramiro Quintá, A. Rea-Rosas, Aiguo Ren, Elena I. Rodríguez-Martínez, Liangyou Rui, Francisco J. Ruíz-Martínez, Hiroyuki Sakurai, Paula Sancho, Carmen Sato-Bigbee, Matthew Selby, Himanshu Sharma, Chigusa Shimizu-Okabe, Cristina Simon-Martinez, M.-O. Soyer-Gobillard, Fiorenza Stagni, Elinor L. Sullivan, Charles Sultan, Masanobu Sunagawa, Ana Carolina Tahira, Chitoshi Takayama, Akihito Takeuchi, Abhijeet Taori, Margot J. Taylor, B. Tervo-Clemmens, Verena Theis, Carsten Theiss, Deanne Kim Thompson, John M.D. Thompson, Bogdan Florin Toma, Raphaele Tsao, Charline Urbain, Verônica Luiza Vale Euclydes Colovati, E.M. Vásquez-Garibay, Karen E. Waldie, Linlin Wang, Tsung-Ung Wilson Woo, Paul Yao, René Zempoalteca, Nanyin Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a3934ab2fbb127732ebb9edcbfe6b4d
https://doi.org/10.1016/b978-0-12-817986-4.01002-6

Changes in the expression and localization of signaling molecules in mouse facial motor neurons during regeneration of facial nerves

Autor: Chitoshi Takayama, Akihito Okabe, Shiori Kobayashi, Taekyun Shin, Chigusa Shimizu-Okabe, Changjong Moon, Jeongtae Kim

Publikováno v: Journal of Chemical Neuroanatomy. 88:13-21

After injury, peripheral axons usually re-extend toward their target, and neuronal functions recover. Previous studies have reported that expression of various molecules are transiently altered in motor neurons after nerve injury, but the time course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6244aa0e8ce5a1c6d4ba7e4a025a80ff
https://doi.org/10.1016/j.jchemneu.2017.11.002

Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice

Autor: Kensuke Egashira, Akihito Yasuoka, Chisayo Kozuka, Hiroaki Masuzaki, Kaku Nakano, Ayano Kinjo, Keiko Abe, Takashi Kondo, Fukuda Kotaro, Chitoshi Takayama, Asuka Kamei, Chigusa Shimizu-Okabe, Morinaga Hidetaka

Publikováno v: Drug Delivery, Vol 24, Iss 1, Pp 558-568 (2017)
Drug Delivery
article-version (VoR) Version of Record

Our previous works demonstrated that brown rice-specific bioactive substance, γ-oryzanol acts as a chaperone, attenuates exaggerated endoplasmic reticulum (ER) stress in brain hypothalamus and pancreatic islets, thereby ameliorating metabolic derang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d12c3fd975b5b729f759a7849fda41e
https://doaj.org/article/8b4813d137704330bf54da9b7008609d