Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chigusa Nakajima"'
Autor:
Kakusho Chigusa Nakajima-Ohyama1,2 kakusho-ohyama@nms.ac.jp, Yoshie Shizusawa3,4, Shotaro Uchiyama1, Yasuhiro Kishi1, Hitoshi Tanimukai5
Publikováno v:
Journal of Nippon Medical School. 2024, Vol. 91 Issue 2, p233-240. 8p.
Efficacy and safety of hangekobokuto ( Banxia‐houpo‐tang ) in treating panic disorder: A pilot study
Publikováno v:
Traditional & Kampo Medicine. 9:180-185
Autor:
Hideyuki Yanai, Chigusa Nakajima, Shizuo Akira, Ai Watanabe, Toshiaki Ohteki, Tadatsugu Taniguchi, Shinya Sakaguchi, Misako Matsumoto, Tsuneyasu Kaisho, Kenya Honda, Tsukasa Seya, Akinori Takaoka
Publikováno v:
Proceedings of the National Academy of Sciences. 100:10872-10877
A complex mechanism may be operational for dendritic cell (DC) maturation, wherein Toll-like receptor and other signaling pathways may be coordinated differently depending on the nature of the pathogens, in order for DC maturation to be most effectiv
Autor:
Hideo Negishi, Chigusa Nakajima, Akinori Takaoka, Tadatsugu Taniguchi, Masataka Asagiri, Tatsuaki Mizutani, Kenya Honda, Shinya Sakaguchi
Publikováno v:
Biochemical and Biophysical Research Communications. 306:860-866
Type I interferons (IFN-α/β) affect many aspects of immune responses. Many pathogen-associated molecules, including bacterial lipopolysaccharide (LPS) and virus-associated double-stranded RNA, induce IFN gene expression through activation of distin
A critical role for IL-12 in CCR5 induction on T cell receptor-triggered mouse CD4+ and CD8+ T cells
Autor:
Ping Gao, Michio Tomura, Woong Ryeon Park, Hiromi Fujiwara, Toshiyuki Hamaoka, Masayuki Iwasaki, Chigusa Nakajima, Takao Mukai
Publikováno v:
European Journal of Immunology. 31:2411-2420
Despite increasing evidence for the role of the chemokine system in leukocyte trafficking, the mechanism underlying the induction of chemokine receptors is poorly understood. Here, we investigated how CCR5, a chemokine receptor implicated in T cell m
Autor:
Takahiro Tsujimura, Masakiyo Nakahira, Yi-Fu Yang, Masayuki Iwasaki, Chigusa Nakajima, Ping Gao, Shiro Ono, Toshiyuki Hamaoka, Hiromi Fujiwara, Yasuhiro Uekusa
Publikováno v:
Journal of Immunotherapy. 23:643-653
Interleukin-12 (IL-12) treatment is effective in the CSA1M but not in the Meth A and CSA1M-variant tumor models. The authors investigated the cause by which IL-12 treatment fails to induce tumor regression in these two tumor models. T cells from CSA1
Autor:
Chigusa Nakajima, Toshiyuki Hamaoka, Ping Gao, Masayuki Iwasaki, Yasuhiro Uekusa, Rishani Wijesuriya, Wen Gong Yu, Yi Fu Yang, Hiromi Fujiwara
Publikováno v:
International Immunology. 12:701-709
While IL-12 administration induces tumor regression through stimulating T cells in tumor-bearing mice, this IL-12 effect is observed in some but not all tumor models. The present study aimed to compare IL-12 responsiveness of T cells from tumor-beari
Autor:
Chigusa Nakajima, Masayuki Iwasaki, Michio Tomura, Yasuhiro Uekusa, Mitsuhiro Nakazawa, Nobuya Yamaguchi, Ping Gao, Toshiyuki Hamaoka, Takao Mukai, Noritame Takeuchi, Hiromi Fujiwara, Takahiro Tsujimura
Publikováno v:
Journal of leukocyte biology. 72(5)
Interleukin (IL)-12 plays a central role in the initiation and regulation of T cell-mediated immune responses. The present study investigated how IL-12, endogenously produced during tumor vaccination, functions for anti-tumor immune responses. Mice w
Autor:
Chigusa, Nakajima, Takao, Mukai, Nobuya, Yamaguchi, Yasunari, Morimoto, Woong-Ryeon, Park, Masayuki, Iwasaki, Ping, Gao, Shiro, Ono, Hiromi, Fujiwara, Toshiyuki, Hamaoka
Publikováno v:
European journal of immunology. 32(6)
The chemokine receptor CXCR3 has been shown to play a key role in the recruitment of T cells to sites of inflammation such as allografts. Here, we investigated which signals and conditions areresponsible for CXCR3 induction. CXCR3 was induced on T ce
Autor:
Toshiyuki Hamaoka, Chigusa Nakajima, Ping Gao, Masayuki Iwasaki, Michio Tomura, Hiromi Fujiwara, Yi-Fu Yang, Nobuya Yamaguchi, Takao Mukai
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 167(12)
IL-12 was recently shown to induce CCR5 on TCR-triggered mouse T cells. Considering that STAT4 is the most critical of IL-12 signaling molecules, this study investigated the role for STAT4 in the induction of CCR5 expression. IL-12R was induced by st